公开(公告)号：US20210388014A1

公开(公告)日：2021-12-16

申请号：US17286474

申请日：2019-10-17

Applicant: BASF SE

Inventor： Michael PUHL ,  Sebastian WLOCH ,  Peter OEDMAN ,  Anne-Catrin LETZEL ,  Hartwing SCHROEDER ,  Jacek MALISZ ,  Daniel SEIBERT-LUDWIG ,  Emiel Jan KAPPERT ,  Chung Huan WONG ,  Michael BARROS GROSS ,  Martin VIERTELHAUS

IPC: C07H1/08 ,  C07H3/06

Abstract: The present invention relates to a method for obtaining crystalline 2′-fucosyllactose from a 2′-FL raw material, which contains 2′-FL as a main constituent and at least 0.5% by weight, frequently at least 1% by weight, in particular at least 2% by weight, more particularly at least 5% by weight, and especially at least 8% by weight,based on the total amount of mono-and oligosaccharides in the raw material, of one or more mono- or oligosaccharides different from 2′-FL, where the method comprises a)providing a solution of the 2′-FL raw material in water, which does not contain more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents, based on the total amount of water; b) effecting the crystallization of 2′-FL from the solution provided in step a) by inducing conditions of a controlled super saturation in the solution; and c) separating crystalline 2′-FL from the mother liquor, and where during controlled supersaturation in step b) not more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents are present, based on the total amount of water present during step b).

公开(公告)号：US20230227487A1

公开(公告)日：2023-07-20

申请号：US18008684

申请日：2021-06-10

Applicant: BASF SE

Inventor： Johan Fredrik BILLING ,  Emiel Jan KAPPERT ,  Chung Huan WONG ,  Jacek MALISZ

IPC: C07H1/08 ,  C07H3/06 ,  A23C9/142 ,  A23C9/146

CPC classification number: C07H1/08 ,  A23C9/142 ,  A23C9/146 ,  C07H3/06 ,  C12P19/04

Abstract: The present invention relates to a method for improved demineralization of fermentation broths, including the steps of providing a solution comprising one or more oligosaccharides, carrying out a first membrane filtration and preferably being a microfiltration or ultrafiltration, a second membrane filtration of the permeate of the first membrane filtration and a first nanofiltration step; with a sub-step of concentration and/or a sub-step of diafiltration. Moreover, the present invention is directed to an improved purification of fine chemicals from a fermentation broth.

公开(公告)号：US20170334824A1

公开(公告)日：2017-11-23

申请号：US15522550

申请日：2015-11-06

Applicant: BASF SE

Inventor： Ralf PELZER ,  Carolin REGENBRECHT ,  Chung Huan WONG ,  Gabriele IFFLAND ,  Agnes VOITL

IPC: C07C45/79 ,  C07C47/58

CPC classification number: C07C45/79 ,  B01D15/00 ,  C07C47/58

Abstract: The present invention relates to a method for extracting aromatic compounds from aqueous, alkaline compositions containing lignin, which have a pH value of at least pH 10, in particular of at least pH 11, especially of at least pH 12, characterized in that the aqueous, alkaline composition containing lignin is treated with active carbon, the active carbon separates from the aqueous, alkaline composition containing lignin and the active carbon then undergoes a desorption step in order to extract the aromatic compounds, wherein the desorption step comprises the treatment of the active carbon (i) by means of an organic solvent, which essentially consists of one or more aromatic hydrocarbons or a mixture of at least one aromatic hydrocarbon together with at least one C1-C4 alkanol, or (ii) by means of water vapor, wherein an eluate is obtained which contains the aromatic compounds.