公开(公告)号：US20240101575A1

公开(公告)日：2024-03-28

申请号：US18272820

申请日：2022-01-21

Applicant: BASF SE

Inventor： Christopher Koradin ,  Martin John McLaughlin ,  Roland Goetz ,  Rahul Kaduskar ,  Harish Shinde

IPC: C07D513/04

CPC classification number: C07D513/04

Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium-5-olate.

公开(公告)号：US20240101516A1

公开(公告)日：2024-03-28

申请号：US18272673

申请日：2022-01-17

Applicant: BASF SE

Inventor： Rahul Kaduskar ,  Kailaskumar Borate ,  Suyog Adhav ,  Saravanan Thirunavukkarasu ,  Harish Shinde ,  Roland Goetz

IPC: C07D213/75 ,  C07C231/12

CPC classification number: C07D213/75 ,  C07C231/12

Abstract: The presently claimed invention relates to a process for the preparation of mono-, di-, tri-, fluoro arylamide or hetroarylamide.

公开(公告)号：US20240389591A1

公开(公告)日：2024-11-28

申请号：US18685970

申请日：2022-08-19

Applicant: BASF SE

Inventor： Rahul Kaduskar ,  Martin Viertelhaus ,  Sunil Kolse ,  Desislava Slavcheva Petkova ,  Tobias Seiser ,  Roland Goetz ,  Harish Shinde ,  Henning Urch ,  Ricardo Hugo Pavon Romero

IPC: A01N43/54 ,  A01N25/04 ,  A01P13/00 ,  C07D239/54

Abstract: The present invention relates to one crystalline form A of methyl 2-[2-[2-bromo-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)pyrimidin-1-yl]phenoxy]phenoxy]-2-methoxy-acetate, a process for the production of this crystalline form and formulations for plant protection comprising such form A.

公开(公告)号：US20230322693A1

公开(公告)日：2023-10-12

申请号：US18028129

申请日：2021-09-28

Applicant: BASF SE

Inventor： Christopher Koradin ,  Harish Shinde ,  Martin John McLaughlin ,  Rahul Kaduskar ,  Philipp M. Staehle ,  Roland Goetz ,  Sunil Khamkar

IPC: C07D277/56

CPC classification number: C07D277/56

Abstract: The present invention relates to a process for the preparation 2-chloro-1-(2-chlorothiazol-5-yl)ethanone.

公开(公告)号：US20230100114A1

公开(公告)日：2023-03-30

申请号：US17917301

申请日：2021-04-06

Applicant: BASF SE

Inventor： Kailaskumar Borate ,  Saravanan Thirunavukkarasu ,  Rahul Kaduskar ,  Harish Shinde ,  Roland Goetz

IPC: C07C209/10 ,  B01J31/22 ,  B01J31/18

Abstract: The presently claimed invention relates to a process for the preparation of di-, tri-, or tetra fluoroarylamine by reacting polyfluorinated aryl chlorides with ammonia in the presence of a base, a metal catalyst and a ligand. Di-, tri-, tetrafluoroarylamines are valuable intermediates and find application in several areas, mainly in epoxy polymers, colorants, dyes, polyurethanes, agrochemicals and pharmaceutical active agents.

公开(公告)号：US20240101547A1

公开(公告)日：2024-03-28

申请号：US18272840

申请日：2022-01-21

Applicant: BASF SE

Inventor： Christopher Koradin ,  Martin John McLaughlin ,  Roland Goetz ,  Rahul Kaduskar ,  Harish Shinde ,  Guillaume Michel Jacques Garivet

IPC: C07D417/12

CPC classification number: C07D417/12

Abstract: The present invention relates to a method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof, to 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof and to its use as intermediate in the preparation of 2,3-dihydrotheiazolo [3,2-a]pyrimidinium compounds, and specifically of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo [3,2-a]pyrimidin-4-ium-5-olate and enantiomerically enriched forms thereof.

公开(公告)号：US20240262816A1

公开(公告)日：2024-08-08

申请号：US18282874

申请日：2022-03-25

Applicant: BASF SE

Inventor： Martin John McLaughlin ,  Christopher Koradin ,  Rahul Kaduskar ,  Harish Shinde ,  Roland Goetz

IPC: C07D417/12 ,  B01J31/18

CPC classification number: C07D417/12 ,  B01J31/189

Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 2-[2-(2-chlorothiazol-5-yl)-2-hydroxy-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one of the formula (I) by hydrogenation of 2-[2-(2-chlorothia-201-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one (1) in the presence of a chiral transition metal catalyst.

公开(公告)号：US20240116916A1

公开(公告)日：2024-04-11

申请号：US18272913

申请日：2022-01-21

Applicant: BASF SE

Inventor： Martin John McLaughlin ,  Christopher Koradin ,  Rahul Kaduskar ,  Harish Shinde ,  Roland Gotez ,  Guillaume Michel Jacques Garivet

IPC: C07D417/12 ,  B01J31/18

CPC classification number: C07D417/12 ,  B01J31/1805 ,  C07B2200/07

Abstract: The present invention relates to a method for preparing 2-[2-(2-chlorothiazol-5-yl)-2- hydroxy-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof or enantiomerically enriched forms thereof, to 2-[2-(2-chlorothiazol-5-yl)-2-hydroxy-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one or a tautomer thereof or enantiomerically enriched forms thereof, and to the use thereof as intermediate in the preparation of 2,3-dihydrothiazolo[3,2-a]pyrimidinium compounds, specifically of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo [3,2-a]pyrimidin-4-ium-5-olate and enantiomerically enriched forms thereof.

公开(公告)号：US20240051929A1

公开(公告)日：2024-02-15

申请号：US17641989

申请日：2020-09-28

Applicant: BASF SE

Inventor： Harish Shinde ,  Rahul Kaduskar ,  Christopher Koradin ,  Martin John McLaughlin ,  Roland Goetz ,  Sunil Khamkar

IPC: C07D277/32

CPC classification number: C07D277/32

Abstract: The present invention relates to a process for the preparation 2-chloro-1-(2-chlorothiazol-5-yl)ethanone.

公开(公告)号：US20230416273A1

公开(公告)日：2023-12-28

申请号：US18272884

申请日：2022-01-21

Applicant: BASF SE

Inventor： Christopher Koradin ,  Martin John McLaughlin ,  Harish Shinde ,  Rahul Kaduskar ,  Ronald Goetz ,  Guillaaume Michel Jaques Garivet

IPC: C07D513/04

CPC classification number: C07D513/04

Abstract: The present invention relates to a method for preparing an enantiomerically enriched form of 3-(2-chlorothiazol-5-yl)-8-methyl-7-oxo-6-phenyl-2,3-dihydrothiazolo[3,2-a]pyrimidin-4-ium-5-olate.