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公开(公告)号：US20240059448A1
公开(公告)日：2024-02-22
申请号：US18265758
申请日：2021-12-21
发明人： Atul Malhotra , Gianni Di Stefani
IPC分类号： B65B65/00 , B65B3/00 , B65B3/04 , B65B3/12 , B65B39/00 , B65B51/14 , B65B51/22 , B65B55/12 , B65B61/06 , B65B57/04
CPC分类号： B65B65/006 , B65B3/003 , B65B3/045 , B65B3/12 , B65B39/001 , B65B51/142 , B65B51/225 , B65B55/12 , B65B61/06 , B65B57/04 , A61J1/10
摘要： A cartridge assembly for a filling machine includes a plurality of containers. Each container includes a volume and a stem connected to the volume. A connection line grid is in fluid communication with each stem of the plurality of containers. The connection line grid includes a first row connected to one or more containers of the plurality of containers and a second row connected to one or more containers of the plurality of containers. A filter assembly is coupled to the connection line grid.
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公开(公告)号：US20240043155A1
公开(公告)日：2024-02-08
申请号：US18265741
申请日：2021-12-21
发明人： Atul Malhotra , Gianni Di Stefani
IPC分类号： B65B57/04 , B65B3/00 , B65B3/04 , B65B3/12 , B65B37/06 , B65B39/00 , B65B51/22 , B65B51/14 , B65B55/12 , B65B61/06 , B65B65/00
CPC分类号： B65B57/04 , B65B3/003 , B65B3/045 , B65B3/12 , B65B37/06 , B65B39/001 , B65B51/225 , B65B51/142 , B65B55/12 , B65B61/06 , B65B65/006
摘要： A method for producing sterile solution-filled containers includes positioning a cartridge onto a filling machine. The cartridge includes a plurality of containers, a filter assembly, and a connection line in fluid communication with the filter assembly. Each of the plurality of containers includes a volume and a stem in fluid communication with the volume and in fluid communication with the connection line. The method includes coupling the cartridge to a feed line in fluid communication with a mix tank, activating a pump coupled to the feed line, and at least partially filling one or more of the volumes associated with the plurality of containers by pumping fluid through the feed line, the filter assembly, and the connection line to create one or more at least partially filled containers. Further, the method includes sealing and separating each of the filled and sealed containers from the connection line.
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公开(公告)号：US11654085B2
公开(公告)日：2023-05-23
申请号：US16415767
申请日：2019-05-17
发明人： Atul Malhotra , Gianni Di Stefani , John Doherty , Mark Timothy Foote , Eric J. Henaut , Stephane Spataro , Johanny Stanus , Joost M. Vancaillie
IPC分类号： A61J1/20 , A61J1/14 , A61J1/10 , B65B3/00 , B65B3/02 , B65B55/02 , B65B3/04 , B65D81/32 , B65B31/04 , B65D25/08
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/1468 , A61J1/1475 , A61J1/2024 , B65B3/003 , B65B3/02 , B65B3/04 , B65B55/02 , B65D81/3266 , A61J1/1406 , B65B31/042 , B65B31/043 , B65B31/048 , B65D25/08 , B65D81/32
摘要： A multiple chamber container forming and filling method includes (i) forming at least one strong seal around a periphery of first and second sheets so as to leave an opening between the first and second sheets; (ii) forming a temporary peel seal across the opening; (iii) forming a mixing peel seal between the first and second sheets so as to separate a diluent chamber from a powdered drug chamber; (iv) adding diluent to the diluent chamber; (v) sterilizing the multiple chamber container including the diluent; (vi) opening the temporary peel seal in an aseptic environment; (vii) adding powdered drug to the powdered drug chamber through the opening; and (viii) strong sealing the opening so as to be closed.
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公开(公告)号：US20190350811A1
公开(公告)日：2019-11-21
申请号：US16415767
申请日：2019-05-17
发明人： Atul Malhotra , Gianni Di Stefani , John Doherty , Mark Timothy Foote , Eric J. Henaut , Stephane Spataro , Johanny Stanus , Joost M. Vancaillie
摘要： A multiple chamber container forming and filling method includes (i) forming at least one strong seal around a periphery of first and second sheets so as to leave an opening between the first and second sheets; (ii) forming a temporary peel seal across the opening; (iii) forming a mixing peel seal between the first and second sheets so as to separate a diluent chamber from a powdered drug chamber; (iv) adding diluent to the diluent chamber; (v) sterilizing the multiple chamber container including the diluent; (vi) opening the temporary peel seal in an aseptic environment; (vii) adding powdered drug to the powdered drug chamber through the opening; and (viii) strong sealing the opening so as to be closed.
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公开(公告)号：US20190350810A1
公开(公告)日：2019-11-21
申请号：US16415736
申请日：2019-05-17
发明人： Gianni Di Stefani , John Doherty , Mark Timothy Foote , Eric J. Henaut , Atul Malhotra , Stephane Spataro , Johanny Stanus , Joost M. Vancaillie
摘要： A multiple chamber container includes a first sheet; a second sheet; a first peel seal between the first and second sheets, the first peel seal extending across the first and second sheets; wherein at a first time at least one strong seal is provided around a periphery of the first and second sheets so as to leave an opening between the first and second sheets, and wherein a second peel seal is provided between the first and second sheets, the second peel seal extending across the opening between the first and second sheets; and wherein at a second time the second peel seal is removed and the at least one strong seal is extended to seal the opening between the first and second sheets.
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