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公开(公告)号:US09949978B2
公开(公告)日:2018-04-24
申请号:US15288982
申请日:2016-10-07
发明人: Chantal Fürstner , Jens Ackerstaff , Alexander Straub , Heinrich Meier , Hanna Tinel , Katja Zimmermann , Adrian Tersteegen , Dmitry Zubov , Raimund Kast , Jens Schamberger , Martina Schäfer , Kirsten Börngen
IPC分类号: A61K31/506 , A61K31/513 , C07D413/14 , C07D401/04 , C07D403/04 , C07D409/14 , C07D413/04 , C07D417/04 , C07D471/04 , A61K45/06 , C07D405/14 , C07D417/14 , A61K31/538 , A61K31/536
CPC分类号: A61K31/513 , A61K31/506 , A61K31/536 , A61K31/538 , A61K45/06 , C07D401/04 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04
摘要: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.
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公开(公告)号:US09949977B2
公开(公告)日:2018-04-24
申请号:US15288968
申请日:2016-10-07
发明人: Chantal Fürstner , Jens Ackerstaff , Alexander Straub , Heinrich Meier , Hanna Tinel , Katja Zimmermann , Adrian Tersteegen , Dmitry Zubov , Raimund Kast , Jens Schamberger , Martina Schäfer , Kirsten Börngen
IPC分类号: A61K31/506 , A61K31/513 , C07D413/14 , C07D401/04 , C07D403/04 , C07D409/14 , C07D413/04 , C07D417/04 , C07D471/04 , A61K45/06 , C07D405/14 , C07D417/14 , A61K31/538 , A61K31/536
CPC分类号: A61K31/513 , A61K31/506 , A61K31/536 , A61K31/538 , A61K45/06 , C07D401/04 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04
摘要: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.
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公开(公告)号:US20150148340A1
公开(公告)日:2015-05-28
申请号:US14399945
申请日:2013-05-03
发明人: Chantal Fürstner , Jens Ackerstaff , Alexander Straub , Heinrich Meier , Hanna Tinel , Katja Zimmermann , Adrian Tersteegen , Dmitry Zubov , Raimund Kast , Jens Schamberger , Martina Schäfer , Kirsten Börngen
IPC分类号: C07D417/14 , A61K31/513 , C07D405/14 , A61K45/06 , C07D417/04 , C07D401/04 , C07D409/14 , C07D403/04 , C07D413/04
CPC分类号: A61K31/513 , A61K31/506 , A61K31/536 , A61K31/538 , A61K45/06 , C07D401/04 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04
摘要: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.
摘要翻译: 本申请涉及新颖的双环取代的尿嘧啶衍生物,其制备方法,单独使用或组合用于治疗和/或预防疾病,以及其用于生产用于治疗和/或预防 疾病
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公开(公告)号:US20160244415A1
公开(公告)日:2016-08-25
申请号:US15034995
申请日:2014-11-05
发明人: Chantal Furstner , Jens Ackerstaff , Alexander Straub , Heinrich Meier , Hanna Tinel , Katja Zimmermann , Dmitry Zubov , Jens Schamberger
IPC分类号: C07D239/557 , A61K31/513 , C07D413/10 , C07D413/04 , C07D417/04 , A61K9/08 , C07D403/14 , C07D417/14 , C07D413/14 , A61K45/06 , A61K9/00 , A61K9/20 , C07D403/10 , C07D403/04
CPC分类号: C07D239/557 , A61K9/0053 , A61K9/08 , A61K9/20 , A61K31/513 , A61K45/06 , C07D239/54 , C07D403/04 , C07D403/10 , C07D403/12 , C07D403/14 , C07D413/04 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14
摘要: Substituted uracil derivatives of formula (I), processes for their preparation, their use alone or in combinations for the treatment and/or prophylaxis of diseases, and their use for preparing medicaments for the treatment and/or prophylaxis of diseases.
摘要翻译: 式(I)的取代的尿嘧啶衍生物,其制备方法,其单独使用或组合用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病的药物的用途。
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公开(公告)号:US10300062B2
公开(公告)日:2019-05-28
申请号:US15912185
申请日:2018-03-05
发明人: Chantal Fürstner , Jens Ackerstaff , Alexander Straub , Heinrich Meier , Hanna Tinel , Katja Zimmermann , Adrian Tersteegen , Dmitry Zubov , Raimund Kast , Jens Schamberger , Martina Schäfer , Kirsten Börngen
IPC分类号: A61K31/513 , C07D413/14 , C07D401/04 , C07D403/04 , C07D409/14 , C07D413/04 , C07D417/04 , C07D471/04 , A61K45/06 , C07D405/14 , C07D417/14 , A61K31/538 , A61K31/506 , A61K31/536
摘要: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.
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公开(公告)号:US09751843B2
公开(公告)日:2017-09-05
申请号:US15034499
申请日:2014-11-05
发明人: Chantal Fürstner , Jens Ackerstaff , Alexander Straub , Heinrich Meier , Hanna Tinel , Katja Zimmermann , Adrian Tersteegen , Dmitry Zubov , Raimund Kast , Jens Schamberger , Martina Schäfer
IPC分类号: C07D239/557 , C07D413/14 , C07D403/10 , C07D413/10 , A61K31/513 , C07D409/06 , C07D417/10
CPC分类号: C07D239/557 , A61K31/513 , C07D403/10 , C07D409/06 , C07D413/10 , C07D413/14 , C07D417/10
摘要: Substituted uracil derivatives of the compound of Formula (I), processes for their preparation, their use alone or in combinations for treatment and/or prophylaxis of diseases, and their use for preparing medicaments for treatment and/or prophylaxis of diseases.
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公开(公告)号:US09695131B2
公开(公告)日:2017-07-04
申请号:US15034995
申请日:2014-11-05
发明人: Chantal Fürstner , Jens Ackerstaff , Alexander Straub , Heinrich Meier , Hanna Tinel , Katja Zimmermann , Dmitry Zubov , Jens Schamberger
IPC分类号: C07D403/04 , C07D239/557 , C07D403/12 , C07D403/10 , C07D239/54 , C07D413/04 , C07D413/10 , C07D413/12 , C07D417/04 , C07D417/12 , A61K9/00 , A61K9/08 , A61K9/20 , A61K31/513 , A61K45/06 , C07D403/14 , C07D413/14 , C07D417/14
CPC分类号: C07D239/557 , A61K9/0053 , A61K9/08 , A61K9/20 , A61K31/513 , A61K45/06 , C07D239/54 , C07D403/04 , C07D403/10 , C07D403/12 , C07D403/14 , C07D413/04 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/12 , C07D417/14
摘要: Substituted uracil derivatives of formula (I), processes for their preparation, their use alone or in combinations for the treatment and/or prophylaxis of diseases, and their use for preparing medicaments for the treatment and/or prophylaxis of diseases.
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公开(公告)号:US09481672B2
公开(公告)日:2016-11-01
申请号:US14399945
申请日:2013-05-03
发明人: Chantal Fürstner , Jens Ackerstaff , Alexander Straub , Heinrich Meier , Hanna Tinel , Katja Zimmermann , Adrian Tersteegen , Dmitry Zubov , Raimund Kast , Jens Schamberger , Martina Schäfer , Kirsten Börngen
IPC分类号: A61K31/513 , C07D417/14 , C07D413/14 , C07D401/04 , C07D403/04 , C07D409/14 , C07D413/04 , C07D417/04 , C07D471/04 , A61K45/06 , C07D405/14
CPC分类号: A61K31/513 , A61K31/506 , A61K31/536 , A61K31/538 , A61K45/06 , C07D401/04 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04
摘要: The present application relates to novel bicyclically substituted uracil derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases.
摘要翻译: 本申请涉及新颖的双环取代的尿嘧啶衍生物,其制备方法,单独使用或组合用于治疗和/或预防疾病,以及其用于生产用于治疗和/或预防 疾病
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