公开(公告)号：US20190101438A1

公开(公告)日：2019-04-04

申请号：US16152643

申请日：2018-10-05

Applicant: Beckman Coulter, Inc.

Inventor： Michael M. Morrell ,  Timothy Reed

IPC: G01J1/04 ,  G01N21/85 ,  G01N21/59 ,  G01N21/53 ,  G01N15/14

Abstract: A filter mask for use in a flow cytometer includes light blocking features and light passing apertures. The flow cytometer operates to evaluate one or more characteristics of a sample by illuminating the sample and a carrier fluid and collecting light rays that are radiated from the sample and the carrier fluid. The light rays are passed through the filter mask. The light blocking features of the filter mask are arranged to selectively block radiated light at certain radiation angles, while permit light rays having other radiation angles to pass therethrough. A sensor analyzer receives the light rays that pass through to evaluate at least one characteristic of the sample. The light rays can also be separated into two beams, which can be independently filtered using different filter masks. The results can then be compared to provide even more information regarding characteristics of the sample.

公开(公告)号：US10101260B2

公开(公告)日：2018-10-16

申请号：US14776888

申请日：2014-03-12

Applicant: BECKMAN COULTER, INC.

Inventor： Timothy Reed ,  Michael M. Morrell

IPC: G01N21/00 ,  G01N15/14 ,  G01N21/53 ,  G02B19/00

Abstract: A flow cytometer includes a flow nozzle, a light source, an optics system, and a sensor analyzer. The flow nozzle provides a fluid along a flow path. The light source generates a light beam that illuminates the fluid. The optics system collects light rays that are radiated from the light beam by the fluid and passes or blocks the light rays based at least in part on the radiation angles associated with the light rays.

公开(公告)号：US10132678B2

公开(公告)日：2018-11-20

申请号：US15878527

申请日：2018-01-24

Applicant: Beckman Coulter, Inc.

Inventor： Michael M. Morrell ,  Timothy Reed

IPC: G01J1/04 ,  G01N21/85 ,  G01N21/53 ,  G01N15/14 ,  G01N21/59 ,  G01N15/10

Abstract: A filter mask for use in a flow cytometer includes light blocking features and light passing apertures. The flow cytometer operates to evaluate one or more characteristics of a sample by illuminating the sample and a carrier fluid and collecting light rays that are radiated from the sample and the carrier fluid. The light rays are passed through the filter mask. The light blocking features of the filter mask are arranged to selectively block radiated light at certain radiation angles, while permit light rays having other radiation angles to pass therethrough. A sensor analyzer receives the light rays that pass through to evaluate at least one characteristic of the sample. The light rays can also be separated into two beams, which can be independently filtered using different filter masks. The results can then be compared to provide even more information regarding characteristics of the sample.

公开(公告)号：US09885603B2

公开(公告)日：2018-02-06

申请号：US14776878

申请日：2014-03-14

Applicant: BECKMAN COULTER, INC.

Inventor： Michael M. Morrell ,  Timothy Reed

IPC: G01J1/04 ,  G01N21/85 ,  G01N21/53 ,  G01N15/14 ,  G01N21/59 ,  G01N15/10

CPC classification number: G01J1/0488 ,  G01N15/1434 ,  G01N15/1459 ,  G01N21/53 ,  G01N21/59 ,  G01N21/85 ,  G01N2015/1006

Abstract: A filter mask for use in a flow cytometer includes light blocking features and light passing apertures. The flow cytometer operates to evaluate one or more characteristics of a sample by illuminating the sample and a carrier fluid and collecting light rays that are radiated from the sample and the carrier fluid. The light rays are passed through the filter mask. The light blocking features of the filter mask are arranged to selectively block radiated light at certain radiation angles, while permit light rays having other radiation angles to pass therethrough. A sensor analyzer receives the light rays that pass through to evaluate at least one characteristic of the sample. The light rays can also be separated into two beams, which can be independently filtered using different filter masks. The results can then be compared to provide even more information regarding characteristics of the sample.

公开(公告)号：US10473519B2

公开(公告)日：2019-11-12

申请号：US16152643

申请日：2018-10-05

Applicant: Beckman Coulter, Inc.

Inventor： Michael M. Morrell ,  Timothy Reed

IPC: G01J1/04 ,  G01N21/85 ,  G01N21/59 ,  G01N21/53 ,  G01N15/14 ,  G01N15/10

Abstract: A filter mask for use in a flow cytometer includes light blocking features and light passing apertures. The flow cytometer operates to evaluate one or more characteristics of a sample by illuminating the sample and a carrier fluid and collecting light rays that are radiated from the sample and the carrier fluid. The light rays are passed through the filter mask. The light blocking features of the filter mask are arranged to selectively block radiated light at certain radiation angles, while permit light rays having other radiation angles to pass therethrough. A sensor analyzer receives the light rays that pass through to evaluate at least one characteristic of the sample. The light rays can also be separated into two beams, which can be independently filtered using different filter masks. The results can then be compared to provide even more information regarding characteristics of the sample.

公开(公告)号：US20180149517A1

公开(公告)日：2018-05-31

申请号：US15878527

申请日：2018-01-24

Applicant: Beckman Coulter, Inc.

Inventor： Michael M. Morrell ,  Timothy Reed

IPC: G01J1/04 ,  G01N21/85 ,  G01N21/59 ,  G01N15/14

CPC classification number: G01J1/0488 ,  G01N15/1434 ,  G01N15/1459 ,  G01N21/53 ,  G01N21/59 ,  G01N21/85 ,  G01N2015/1006

Abstract: A filter mask for use in a flow cytometer includes light blocking features and light passing apertures. The flow cytometer operates to evaluate one or more characteristics of a sample by illuminating the sample and a carrier fluid and collecting light rays that are radiated from the sample and the carrier fluid. The light rays are passed through the filter mask. The light blocking features of the filter mask are arranged to selectively block radiated light at certain radiation angles, while permit light rays having other radiation angles to pass therethrough. A sensor analyzer receives the light rays that pass through to evaluate at least one characteristic of the sample. The light rays can also be separated into two beams, which can be independently filtered using different filter masks. The results can then be compared to provide even more information regarding characteristics of the sample.