公开(公告)号：US3737375A

公开(公告)日：1973-06-05

申请号：US3737375D

申请日：1970-11-25

申请人： BIOCHEMIE GMBH

发明人： BRANDL E ,  KLEIBER W ,  KNAUSEDER F

IPC分类号： C12P37/06 ,  A61K31/43 ,  C07C20060101 ,  C07D20060101 ,  C07D499/10 ,  C07D499/42 ,  C12R1/01 ,  C12D9/00

CPC分类号： C07D499/42 ,  Y10S435/911

摘要： THE INVENTION CONCERNS A NOVEL CLEAVAGE PROCESS FOR THE PRODUCTION OF 6-AMINOPENICILLANIC ACID, WHICH COMPRISES CONTACTING A PENICILLIN OF THE FORMULA:

6-(R-CO-NH-),2-(HOOC-),3,3-DI(CH3-)PENAM

WHEREIN R IS PHENOXYMETHYL, P-CRESOXYMETHYL OR NBUTOXYMETHYL, OR AN ALKALI METAL SALT OF SAID PENICILLIN, WITH PENICILLIN AMIDASE PRODUCED BY CULTURING UNDER AEROBIC CONDITIONS BOVISTA PLUMBEA (NNRL 3501) OR A MUTANT OR VARIANT THEREOF IN AN AQUEOUS MEDIUM CONTAINING ASSIMILABLE SOURCES OF CARBON AND NITROGEN.

公开(公告)号：US3716579A

公开(公告)日：1973-02-13

申请号：US3716579D

申请日：1970-07-20

申请人： BIOCHEMIE GMBH

发明人： KNAUSEDER F ,  BRANDL E

IPC分类号： C12P15/00 ,  A23K1/16 ,  A23K1/17 ,  A61K31/22 ,  C07C69/12 ,  C07C69/145 ,  C07C69/52 ,  C12P1/02 ,  C07C69/16 ,  C12D9/22

CPC分类号： C07C69/16 ,  A23K20/195 ,  C07C2603/82 ,  C12P15/00 ,  Y10S435/911

摘要： The invention concerns new pleuromutilin derivatives of the formula:

WHEREIN R is CH3-(CH2)7-CH CH-(CH2)7-COO-, CH3-(CH2)4-CH CH-CH2CH CH-(CH2)7-COO-, CH3-(CH2)9-CH CH-(CH2)7-COO-, or hydrogen. The derivatives are useful animal feed additives, and also find application in veterinary medicine.

摘要翻译： 本发明涉及下式的新型去甲蝶呤衍生物：