-
公开(公告)号：US11839478B2
公开(公告)日：2023-12-12
申请号：US17215193
申请日：2021-03-29
Inventor： Robert J. Butera , Yogi A. Patel , James D. Ross , Swaminathan Rajaraman , Isaac Clements
CPC classification number: A61B5/294 , A61B5/4041 , A61B5/685 , A61B5/6877 , A61N1/0551 , A61N1/0556 , A61N1/3605 , A61B2562/0209 , A61B2562/046
Abstract: A neural interfacing device is disclosed. The neural interfacing device includes a microneedle electrode. The microneedle electrode includes a body having a void formed therein and a plurality of microneedles. The void surrounds the plurality of microneedles, and the plurality of microneedles are bent outward with respect to the body to form a three-dimensional microneedle electrode. Additionally, each of the plurality of microneedles is sized and shaped to penetrate a nerve epineurium.
-
公开(公告)号：US20210236033A1
公开(公告)日：2021-08-05
申请号：US17215193
申请日：2021-03-29
Inventor： Robert J. Butera , Yogi A. Patel , James D. Ross , Swaminathan Rajaraman , Isaac Clements
Abstract: A neural interfacing device is disclosed. The neural interfacing device includes a microneedle electrode. The microneedle electrode includes a body having a void formed therein and a plurality of microneedles. The void surrounds the plurality of microneedles, and the plurality of microneedles are bent outward with respect to the body to form a three-dimensional microneedle electrode. Additionally, each of the plurality of microneedles is sized and shaped to penetrate a nerve epineurium.
-
Patent Agency Ranking
公开(公告)号：US10959631B2
公开(公告)日：2021-03-30
申请号：US15115772
申请日：2015-02-02
Inventor： Robert J. Butera , Yogi A. Patel , James D. Ross , Swaminathan Rajaraman , Isaac Clements
Abstract: A neural interfacing device is disclosed. The neural interfacing device may include at least one microneedle electrode. The microneedle electrode may have one or more microneedles. The one or more microneedles may be shaped and positioned such that when the neural interfacing device is applied to a nerve, the one or more microneedles penetrate a nerve epineurium without any portion of the microneedle electrode penetrating any nerve axon beyond a depth of 500 micrometers.
-
公开(公告)号：US20170285058A1
公开(公告)日：2017-10-05
申请号：US15623687
申请日：2017-06-15
Applicant: Georgia Tech Research Corporation
Inventor： Edgar A. Brown , James D. Ross , Richard A. Blum , Stephen P. DeWeerth
CPC classification number: G01N37/00 , A61B5/04 , A61B5/04001 , A61B5/7217 , A61N1/3605 , A61N1/3704 , G01N33/4836
Abstract: Disclosed are apparatus and methods that provide the ability to electrical stimulate a physical system, and actively eliminate interference with signal acquisition (artifacts) that arises from the stimulation. The technique implemented in the circuits and methods for eliminating interference connects a discharge path to a physical interface to the system to remove charge that is built-up during stimulation. By placing the discharge path in a feedback loop that includes a recording preamplifier and AC-coupling circuitry, the physical interface is brought back to its pre-stimulation offset voltage. The disclosed apparatus and methods may be used with piezoelectric transducers, ultrasound devices, optical diodes, and polarizable and non-polarizable electrodes. The disclosed apparatus can be employed in implantable devices, in vitro or in vivo setups with vertebrate and invertebrate neural tissue, muscle fibers, pancreatic islet cells, osteoblasts, osteoclasts, bacteria, algae, fungi, protists, and plants.
-
公开(公告)号：US09684008B2
公开(公告)日：2017-06-20
申请号：US14133834
申请日：2013-12-19
Applicant: Georgia Tech Research Corporation
Inventor： Edgar A. Brown , James D. Ross , Richard A. Blum , Stephen P. Deweerth
IPC: A61B5/04 , A61N1/37 , G01N37/00 , G01N33/483 , A61B5/00
CPC classification number: G01N37/00 , A61B5/04 , A61B5/04001 , A61B5/7217 , A61N1/3605 , A61N1/3704 , G01N33/4836
Abstract: Disclosed are apparatus and methods that provide the ability to electrical stimulate a physical system, and actively eliminate interference with signal acquisition (artifacts) that arises from the stimulation. The technique implemented in the circuits and methods for eliminating interference connects a discharge path to a physical interface to the system to remove charge that is built-up during stimulation. By placing the discharge path in a feedback loop that includes a recording preamplifier and AC-coupling circuitry, the physical interface is brought back to its pre-stimulation offset voltage. The disclosed apparatus and methods may be used with piezoelectric transducers, ultrasound devices, optical diodes, and polarizable and non-polarizable electrodes. The disclosed apparatus can be employed in implantable devices, in vitro or in vivo setups with vertebrate and invertebrate neural tissue, muscle fibers, pancreatic islet cells, osteoblasts, osteoclasts, bacteria, algae, fungi, protists, and plants.
-
公开(公告)号：US10712357B2
公开(公告)日：2020-07-14
申请号：US15623687
申请日：2017-06-15
Applicant: Georgia Tech Research Corporation
Inventor： Edgar A. Brown , James D. Ross , Richard A. Blum , Stephen P. DeWeerth
Abstract: Disclosed are apparatus and methods that provide the ability to electrical stimulate a physical system, and actively eliminate interference with signal acquisition (artifacts) that arises from the stimulation. The technique implemented in the circuits and methods for eliminating interference connects a discharge path to a physical interface to the system to remove charge that is built-up during stimulation. By placing the discharge path in a feedback loop that includes a recording preamplifier and AC-coupling circuitry, the physical interface is brought back to its pre-stimulation offset voltage. The disclosed apparatus and methods may be used with piezoelectric transducers, ultrasound devices, optical diodes, and polarizable and non-polarizable electrodes. The disclosed apparatus can be employed in implantable devices, in vitro or in vivo setups with vertebrate and invertebrate neural tissue, muscle fibers, pancreatic islet cells, osteoblasts, osteoclasts, bacteria, algae, fungi, protists, and plants.
-
公开(公告)号：US20140107981A1
公开(公告)日：2014-04-17
申请号：US14133834
申请日：2013-12-19
Applicant: Georgia Tech Research Corporation
Inventor： Edgar A. Brown , James D. Ross , Richard A. Blum , Stephen P. Deweerth
IPC: G01N37/00
CPC classification number: G01N37/00 , A61B5/04 , A61B5/04001 , A61B5/7217 , A61N1/3605 , A61N1/3704 , G01N33/4836
Abstract: Disclosed are apparatus and methods that provide the ability to electrical stimulate a physical system, and actively eliminate interference with signal acquisition (artifacts) that arises from the stimulation. The technique implemented in the circuits and methods for eliminating interference connects a discharge path to a physical interface to the system to remove charge that is built-up during stimulation. By placing the discharge path in a feedback loop that includes a recording preamplifier and AC-coupling circuitry, the physical interface is brought back to its pre-stimulation offset voltage. The disclosed apparatus and methods may be used with piezoelectric transducers, ultrasound devices, optical diodes, and polarizable and non-polarizable electrodes. The disclosed apparatus can be employed in implantable devices, in vitro or in vivo setups with vertebrate and invertebrate neural tissue, muscle fibers, pancreatic islet cells, osteoblasts, osteoclasts, bacteria, algae, fungi, protists, and plants.
Abstract translation: 公开了提供电刺激物理系统的能力的装置和方法，并且主动地消除由刺激产生的信号采集（伪影）的干扰。 在电路中实现的技术和消除干扰的方法将放电路径连接到系统的物理接口，以去除在刺激期间积累的电荷。 通过将放电路径放置在包括记录前置放大器和AC耦合电路的反馈回路中，物理接口被带回其预刺激偏移电压。 所公开的装置和方法可以与压电换能器，超声波装置，光二极管以及可极化和不可极化的电极一起使用。 所公开的装置可用于可植入装置，体外或体内用脊椎动物和无脊椎动物神经组织，肌肉纤维，胰岛细胞，成骨细胞，破骨细胞，细菌，藻类，真菌，原生生物和植物的装置。
-
-
-
-
-
-
Search Results
7
records
(took 0.016 seconds)
