公开(公告)号：US20210254165A1

公开(公告)日：2021-08-19

申请号：US17256811

申请日：2019-06-28

申请人： BIOMÉRIEUX ,  BIOASTER ,  HOSPICES CIVILS DE LYON

发明人： Marine MOMMERT ,  Olivier TABONE ,  Julien TEXTORIS ,  François MALLET

IPC分类号： C12Q1/6883

摘要： A method for determining in vitro or ex vivo the immune status of an individual, preferably a patient, including a step of detecting and/or quantifying the expression of one or more HERV/MaLR sequences in a biological sample of the individual. Also relates to the tools for implementing the method and to the uses thereof.

公开(公告)号：US20240318268A1

公开(公告)日：2024-09-26

申请号：US18572835

申请日：2022-07-07

申请人： BIOMÉRIEUX ,  HOSPICES CIVILS DE LYON ,  UNIVERSITE CLAUDE BERNARD LYON I

发明人： Sophie ASSANT ,  Karen BRENGEL-PESCE ,  Marine MOMMERT

IPC分类号： C12Q1/70 ,  A61B10/00 ,  C12Q1/6851

CPC分类号： C12Q1/701 ,  C12Q1/6851 ,  A61B10/0051 ,  C12Q2600/158

摘要： A method for determining, in vitro or ex vivo, the presence in a patient of an infection by a replicating respiratory virus, including a step i) of determining, in a test sample taken from the mouth or nose of said patient, the level of transcripts of at least one marker gene selected from the interferon-stimulated genes, referred to as ISGs; and associated kits.