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公开(公告)号：US20240247312A1
公开(公告)日：2024-07-25
申请号：US18014801
申请日：2021-07-05
申请人： BIOMÉRIEUX , BIOASTER
发明人： Laurence VACHOT , François MALLET , Guillaume MONNERET , Virginie MOUCADEL , Alexandre PACHOT , Estelle PERONNET , Thomas RIMMELÉ , Julien TEXTORIS , Fabienne VENET
IPC分类号： C12Q1/6883 , C12Q1/6851
CPC分类号： C12Q1/6883 , C12Q1/6851 , C12Q2600/118 , C12Q2600/158
摘要： An in vitro or ex vivo method for determining the risk of incidence of a healthcare-associated infection in a patient, including a step of measuring the expression of at least one gene encoding a pro-inflammatory cytokine receptor located on chromosome 2 in the region 2q11-2q12, in a biological sample from the patient.
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2.发明公开公开(公告)号：US20240118287A1
公开(公告)日：2024-04-11
申请号：US18273340
申请日：2022-02-04
申请人： BIOMÉRIEUX
CPC分类号： G01N33/6851 , H01J49/0418
摘要： An analysis plate configured to allow a characterization of microorganisms by mass spectrometry, wherein the analysis plate includes at least one analysis zone configured for a biological sample containing a population of at least one microorganism, wherein all or part of the analysis zone is made of a porous material, the analysis zone including at least one antimicrobial agent.
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公开(公告)号：US20240085445A1
公开(公告)日：2024-03-14
申请号：US18265565
申请日：2021-12-09
申请人： bioMérieux
CPC分类号： G01N35/1011 , G06T7/0014 , G06T7/73 , G06T7/90 , G01N2035/1025 , G06T2207/30024
摘要： Detection method for sample presence and device associated The invention relates to a detection method of liquid presence inside a well of a transparent or translucent support intended for analysis performed in a device for in vitro detection and/or quantification, the presence of liquid being assessed on the basis of an index of visible pattern likelihood representative of the probability of a pattern to be legible as expected in the field of view of an imager. Said invention allows preventing assay execution without sample and can be applied without wasting sample or sample well support in case of the sample well is not filled by the user. Moreover, this method allows a precise detection of the samples that are transparent or translucent, with low reflectance.
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公开(公告)号：US11860158B2
公开(公告)日：2024-01-02
申请号：US16282558
申请日：2019-02-22
发明人： Johannes Reich , Holger Grallert
CPC分类号： G01N33/5306 , G01N33/50 , G01N33/92 , G01N2400/50
摘要： The invention relates to unmasking endotoxins in compositions so that previously present, but undetectable endotoxins are rendered detectable.
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公开(公告)号：US20230313326A1
公开(公告)日：2023-10-05
申请号：US18014934
申请日：2021-07-05
申请人： BIOMÉRIEUX , BIOASTER
发明人： Laurence VACHOT , François MALLET , Guillaume MONNERET , Virginie MOUCADEL , Alexandre PACHOT , Estelle PERONNET , Thomas RIMMELÉ , Julien TEXTORIS , Fabienne VENET
CPC分类号： C12Q1/702 , C12Q1/689 , C12Q2600/158 , C12Q2600/118
摘要： An in vitro or ex vivo method for determining the risk of complication in a patient, including a step of measuring the expression of C3AR1 in a biological sample from the patient.
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公开(公告)号：US20230211348A1
公开(公告)日：2023-07-06
申请号：US18000866
申请日：2021-06-11
申请人： BIOMÉRIEUX
发明人： Michel GUY , Nicolas DELEPAUT
IPC分类号： B01L9/06
CPC分类号： B01L9/06 , B01L2300/042 , B01L2200/16 , B01L2200/028 , B01L2300/044
摘要： The invention relates to a device comprising:
a support tray (7) for tubes receiving samples to be analyzed, this tray (7) having holes (8) adapted to each receive a tube bearing on the upper surface and with its bottom protruding from the tray;
a lid (10) provided with chimneys (11) arranged according to a distribution similar to the distribution of the holes of the tray, this lid (10) being designed to occupy at least one position of superposition above the tray (7), so that the lid can be removably assembled to the tray to form a unitary assembly for holding the tubes and to position the chimneys (11) above the tubes in order to guide the pipette tips penetrating inside the tubes.-
7.发明申请公开(公告)号：US20220333201A1
公开(公告)日：2022-10-20
申请号：US17764323
申请日：2020-09-25
申请人： BIOMÉRIEUX , BIOASTER , HOSPICES CIVILS DE LYON
发明人： Laurence VACHOT , François MALLET , Guillaume MONNERET , Virginie MOUCADEL , Alexandre PACHOT , Estelle PERONNET , Thomas RIMMELÉ , Julien TEXTORIS , Fabienne VENET
IPC分类号： C12Q1/6883 , G16H50/30
摘要： An in vitro or ex vivo method for determining the risk of occurrence of a healthcare-associated infection in a patient, including a step of measuring the expression of CX3CR1, in a biological sample of said patient.
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公开(公告)号：US11408819B2
公开(公告)日：2022-08-09
申请号：US16310487
申请日：2017-06-13
申请人： BIOMÉRIEUX
发明人： Denis Leroux , Eric Laloum , Pierre Mahe , Rony Midahuen , Philippine Barlas
摘要： A detection of the Gram type of a bacterial strain includes: illumination, in the wavelength range 415 nm-440 nm, of at least one bacterium of said strain having a natural electromagnetic response in said range; acquisition, in the range 415 nm-440 nm, of a light intensity reflected by, or transmitted through, said illuminated bacterium; and determination of the Gram type of the bacterial strain as a function of the light intensity acquired in the range 415 nm-440 nm.
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公开(公告)号：US11098298B2
公开(公告)日：2021-08-24
申请号：US16400520
申请日：2019-05-01
IPC分类号： C12N9/64 , G01N33/579
摘要： The present invention provides a novel method for the recombinant production of Factor C protein from horseshoe crab using a parasitic protozoan expressing the Factor C protein. In particular, the present invention provides a parasitic protozoan host cell harbouring a polynucleotide encoding horseshoe crab Factor C protein, and a method for producing Factor C protein comprising culturing said parasitic protozoan host cell under conditions such that the cells express the horseshoe crab Factor C protein. Furthermore, the present invention provides recombinant Factor C protein produced by the novel method and its use in the detection and/or removal of endotoxin.
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公开(公告)号：US11047514B2
公开(公告)日：2021-06-29
申请号：US15755160
申请日：2016-08-29
申请人： BIOMÉRIEUX
IPC分类号： F16L37/086
摘要： An airtight connection device capable of receiving at least one product from at least one product discharge pipe and transmitting the product to a storage tank. The device includes a first part including at least one coupling for connecting to the product discharge pipe in an airtight manner; and a second part including a coupling for mounting the device to the storage tank in an airtight manner. The second part is coupled to the first part in an airtight manner and is capable of receiving the product from the first part and discharging the product to the storage tank. The device also includes a position sensor that can be operated during the airtight coupling to the storage tank.
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