公开(公告)号：US20160090402A1

公开(公告)日：2016-03-31

申请号：US14847941

申请日：2015-09-08

Applicant: BIOMERIEUX

Inventor： Francois MALLET ,  Guy ORIOL ,  Valerie CHEYNET

IPC: C07K14/005 ,  A61K39/21 ,  C07K16/10 ,  C12N7/00

CPC classification number: C07K14/005 ,  A61K38/162 ,  A61K39/12 ,  A61K39/21 ,  C07K16/1036 ,  C07K2317/34 ,  C12N7/00 ,  C12N2740/10022 ,  C12N2740/10034 ,  C12N2740/10063 ,  G01N2333/15

Abstract: A peptide domain necessary for an interaction between an envelope of a virus belonging to an HERV-W interference group and an hASCT receptor comprises (i) an N-terminus motif having an amino acid sequence selected from the group consisting of: SEQ ID No. 1 to SEQ ID No. 29, (ii) a C-terminus motif having an amino acid sequence selected from the group consisting of: SEQ ID No. 30 to SEQ ID No. 40, and (iii) at least one motif between the N-terminus and the C-terminus, and having an amino acid sequence selected from the group consisting of: SEQ ID No. 41, SEQ ID No. 42 and SEQ ID No. 73.

Abstract translation: 属于HERV-W干扰组的病毒的包膜与hASCT受体之间的相互作用所必需的肽结构域包含（i）具有选自下组的氨基酸序列的N末端基序：SEQ ID No. 1至SEQ ID No.29，（ii）具有选自SEQ ID No.30至SEQ ID No.40的氨基酸序列的C末端基序，和（iii）至少一个位于 N-末端和C-末端，并且具有选自SEQ ID No.41，SEQ ID No.42和SEQ ID No.73的氨基酸序列。