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公开(公告)号：US20210369139A1
公开(公告)日：2021-12-02
申请号：US17329861
申请日：2021-05-25
发明人： Dirk Muessig , Ravi Kiran Kondama Reddy , R. Hollis Whittington , Thomas Doerr , Shayan Guhaniyogi
IPC分类号： A61B5/08 , A61B5/0538 , A61B5/00
摘要： An active medical device, comprising a processor, a memory unit, and at least one of an accelerometer and a detection unit configured to detect a body impedance. During operation, the active medical device carries out the following steps a) measuring a body impedance of a patient with the detection unit during a first period of time to obtain time-dependent impedance data and calculating a power spectral density of the impedance data; b) alternatively or additionally, to step a), measuring an acceleration of a body of the patient with the accelerometer during the first period of time to obtain time-dependent acceleration data and calculating a power spectral density of the acceleration data; c) identifying coughing of the patient on the basis of the calculated power spectral density if at least 1% of all values of the power spectral density have a frequency of at least 1 Hz.
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公开(公告)号：US20210178156A1
公开(公告)日：2021-06-17
申请号：US17117434
申请日：2020-12-10
发明人： Kurt Swenson , Shayan Guhaniyogi , Ravi Kiran Kondama Reddy , Christopher Jones , Madeline Anne Midgett , R. Hollis Whittington
摘要： A leadless pacemaker device configured to provide for an intra-cardiac pacing, including: processing circuitry configured to generate ventricular pacing signals for stimulating ventricular, and a reception device for receiving a sensing signal indicative of an atrial activity, wherein the processing circuitry is configured to detect an atrial event derived from said sensing signal, wherein the atrial event is a valid atrial sense event, where a series of atrial events lie within a range for a normal atrial rate, and/or when the atrial rate variability is within a certain range indicating a regular atrial rhythm, wherein in case a valid atrial sense event is detected, the processing circuitry is further configured to: determine: ventricular pacing events according to atrial events, calculate ventricular-atrial time delays, determine a correction value based a measured time delay and the calculated time delay, and adjust the ventricular pacing timing based on the correction value.
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公开(公告)号：US11456075B2
公开(公告)日：2022-09-27
申请号：US16893645
申请日：2020-06-05
摘要： An implantable medical device includes an electronic processing device configured for processing a physiological signal, a memory, and a communication device for communicating with an external device. The processing device includes a coding module for coding the physiological signal to obtain an output signal for transmission by the communication device to the external device. The coding module is configured to encode the physiological signal using at least one fixed Huffman code table stored in the memory to obtain the output signal.
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公开(公告)号：US11426590B2
公开(公告)日：2022-08-30
申请号：US16905134
申请日：2020-06-18
发明人： Madeline Anne Midgett , R. Hollis Whittington , Ravi Kiran Kondama Reddy , Christopher Jones , Shayan Guhaniyogi , Dirk Muessig , Larry Stotts
摘要： A leadless pacemaker device for providing an intra-cardiac pacing includes processing circuitry configured to generate ventricular pacing signals for stimulating ventricular activity at a ventricular pacing rate, a first sensor configuration receiving a first sense signal, and a second sensor configuration receiving a second sense signal. The processing circuitry derives, in a first sensing state, atrial events from the first sense signal for controlling the ventricular pacing rate based on the atrial events. The processing circuitry switches, based on at least one switching criterion, from the first sensing state to a second sensing state in which the processing circuitry derives atrial events from the second sense signal. The second sense signal is received by the second sensor configuration for detection of atrial events and the second sensor configuration is a motion sensor or a sound sensor. A method for operating the pacemaker device is also provided.
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公开(公告)号：US20240216683A1
公开(公告)日：2024-07-04
申请号：US18563039
申请日：2022-05-02
发明人： Shayan Guhaniyogi , R. Hollis Whittington , Dirk Muessig , Ravi Kiran Kondama Reddy , Pamela Shamsie Victoria Riahi
CPC分类号： A61N1/36031 , A61N1/025 , A61N1/36135 , A61N1/36542 , A61N1/3925
摘要： A medical device for implantation within or mounting on a patient's body includes an accelerator unit, a data memory unit and a processor which are electrically interconnected. Three orthogonal axes (XD, YD, ZD) are defined for the medical device and three orthogonal axes (XP, YP, ZP) are defined for the patient's body. The accelerator unit is configured to determine 3-dimensional proper acceleration data along sensitive axes corresponding to the three orthogonal axes of the medical device (XD, YD, ZD). In order to provide an automatic estimation of medical device orientation with regard to a patient's body (thereby overcoming the drawbacks of manual calibration methods) which does not make a priori assumptions about the device's orientation or specific prevalence, the processor is configured to process said acceleration data determined by the accelerator unit.
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公开(公告)号：US11786143B2
公开(公告)日：2023-10-17
申请号：US17329861
申请日：2021-05-25
发明人： Dirk Muessig , Ravi Kiran Kondama Reddy , R. Hollis Whittington , Thomas Doerr , Shayan Guhaniyogi
IPC分类号： A61B5/08 , A61B5/0538 , A61B5/00
CPC分类号： A61B5/0823 , A61B5/0538 , A61B5/686 , A61B2560/0219 , A61B2562/0219
摘要： An active medical device, comprising a processor, a memory unit, and at least one of an accelerometer and a detection unit configured to detect a body impedance. During operation, the active medical device carries out the following steps: a) measuring a body impedance of a patient with the detection unit during a first period of time to obtain time-dependent impedance data and calculating a power spectral density of the impedance data; b) alternatively or additionally to step a), measuring an acceleration of a body of the patient with the accelerometer during the first period of time to obtain time-dependent acceleration data and calculating a power spectral density of the acceleration data; c) identifying coughing of the patient on the basis of the calculated power spectral density if at least 1% of all values of the power spectral density have a frequency of at least 1 Hz.
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公开(公告)号：US20230091855A1
公开(公告)日：2023-03-23
申请号：US17792031
申请日：2020-12-21
发明人： Madeline Anne Midgett , R. Hollis Whittington , Ravi Kiran Kondama Reddy , Christopher Jones , Shayan Guhaniyogi
摘要： A leadless pacemaker device configured to provide for an intra-cardiac pacing comprises a housing; an electrode arrangement arranged on the housing and configured to receive electrical signals; and a processing circuitry enclosed in the housing and operatively connected to the electrode arrangement, wherein the processing circuitry comprises a first processing channel having a first gain for processing a first processing signal derived from electrical signals received via the electrode arrangement and a second processing channel having a second gain for processing a second processing signal derived from electrical signals received via the electrode arrangement, the second gain being higher than the first gain.
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公开(公告)号：US20230058678A1
公开(公告)日：2023-02-23
申请号：US17980759
申请日：2022-11-04
发明人： Kurt Swenson , Shayan Guhaniyogi , Ravi Kiran Kondama Reddy , Christopher Jones , Madeline Anne Midgett , R. Hollis Whittington
摘要： A leadless pacemaker device configured to provide for an intra-cardiac pacing, including: processing circuitry configured to generate ventricular pacing signals for stimulating ventricular tissue, and a reception device for receiving a sensing signal indicative of an atrial activity, wherein the processing circuitry is configured to detect an atrial event derived from said sensing signal, wherein the atrial event is a valid atrial sense event, where a series of atrial events lie within a range for a normal atrial rate, and/or when the atrial rate variability is within a certain range indicating a regular atrial rhythm, wherein in case a valid atrial sense event is detected, the processing circuitry is further configured to: determine ventricular pacing events according to atrial events, calculate ventricular-atrial time delays, determine a correction value based a measured time delay and the calculated time delay, and adjust the ventricular pacing timing based on the correction value.
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公开(公告)号：US11529521B2
公开(公告)日：2022-12-20
申请号：US17117434
申请日：2020-12-10
发明人： Kurt Swenson , Shayan Guhaniyogi , Ravi Kiran Kondama Reddy , Christopher Jones , Madeline Anne Midgett , R. Hollis Whittington
摘要： A leadless pacemaker device configured to provide for an intra-cardiac pacing, including: processing circuitry configured to generate ventricular pacing signals for stimulating ventricular activity, and a reception device for receiving a sensing signal indicative of an atrial activity, wherein the processing circuitry is configured to detect an atrial event derived from said sensing signal, wherein the atrial event is a valid atrial sense event, where a series of atrial events lie within a range for a normal atrial rate, and/or when the atrial rate variability is within a certain range indicating a regular atrial rhythm, wherein in case a valid atrial sense event is detected, the processing circuitry is further configured to: determine ventricular pacing events according to atrial events, calculate ventricular-atrial time delays, determine a correction value based a measured time delay and the calculated time delay, and adjust the ventricular pacing timing based on the correction value.
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公开(公告)号：US11219768B2
公开(公告)日：2022-01-11
申请号：US16825659
申请日：2020-03-20
发明人： Shayan Guhaniyogi
摘要： An implantable pacemaker is configured to provide electrical pacing pulses to the heart of a patient. The pacemaker has a pulse generator configured to generate the electrical pacing pulses, at least one pacing electrode to apply the electrical pacing pulses to the heart, a sensing unit configured to sense events of electrical activity of a ventricle of the heart, a sensor configured to measure a signal relating to the patient, and a memory configured to store values of a parameter. The pacemaker is configured to be operated in a first mode to generate a reference curve and to select a target range of values of the parameter corresponding to a desired range of atrioventricular delays. The pacemaker is further configured to be operated in a second mode for approaching the target range.
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