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公开(公告)号：US09700440B2
公开(公告)日：2017-07-11
申请号：US13937097
申请日：2013-07-08
发明人： Ullrich Bayer , Bodo Gerold
IPC分类号： A61F2/82 , A61L31/02 , A61L31/08 , A61L31/14 , C23C8/20 , C23C8/22 , C23C8/24 , C23C8/26 , C23C8/30 , C23C8/32
CPC分类号： A61F2/82 , A61L31/022 , A61L31/084 , A61L31/148 , C23C8/20 , C23C8/22 , C23C8/24 , C23C8/26 , C23C8/30 , C23C8/32
摘要： The present invention relates to a method for manufacturing an implant, in particular an intraluminal endoprosthesis, having a body containing metallic material, preferably iron. For controlling the degradation of the implant the method includes the following steps: (a) providing a first part of the implant body; and (b) performing heat treatment which alters the carbon content and/or the boron content and/or the nitrogen content in the structure of a near-surface boundary layer in the first part of the implant body in such a way that strain on the lattice or a lattice transformation, optionally following a subsequent mechanical load, is achieved in the near-surface boundary layer. Such an implant is also described.
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公开(公告)号：US20140030310A1
公开(公告)日：2014-01-30
申请号：US14041378
申请日：2013-09-30
发明人： Ullrich Bayer , Claus Harder , Elisabeta Burean
CPC分类号： A61K9/0012 , A61K33/00 , A61L31/022 , A61L31/146 , A61L31/16
摘要： The present invention relates to a method for manufacturing an implant, in particular an intraluminal endoprosthesis, having a body containing metallic material, preferably iron. The following manufacturing method is provided for promotion of the anti-inflammatory effect of the implant: (i) providing the body of the implant; (ii) producing an at least partially closed pore structure in a portion of the structure of the implant body close to the surface; and (iii) incorporating NOx into the cavities of the pore structure. Also described is an implant manufactured in this manner.
摘要翻译： 本发明涉及用于制造植入物的方法，特别是管腔内假体，其具有包含金属材料，优选铁的主体。 提供以下制造方法用于促进植入物的抗炎作用：（i）提供植入物的主体; （ii）在所述植入体的结构的靠近所述表面的部分结构中产生至少部分闭合的孔结构; 和（iii）将NOx并入孔结构的空腔中。 还描述了以这种方式制造的植入物。
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公开(公告)号：US20130297006A1
公开(公告)日：2013-11-07
申请号：US13937113
申请日：2013-07-08
发明人： Ullrich Bayer , Bodo Gerold
CPC分类号： A61F2/82 , A61L31/022 , A61L31/084 , A61L31/148 , C23C8/20 , C23C8/22 , C23C8/24 , C23C8/26 , C23C8/30 , C23C8/32
摘要： Implant in the form of an intraluminal endoprosthesis, having a tubular body containing metallic material, optionally iron, whereby in at least a portion of the implant body the following are present in the structure of a near-surface boundary layer in comparison to the respective concentration in the remaining structure: an increased carbon content in a concentration of approximately 0.5% by weight to approximately 2% by weight; or an increased carbon and nitrogen content, wherein a concentration of carbon is approximately 0.5% by weight to approximately 7% by weight, and a concentration of nitrogen is approximately 0.5% by weight to approximately 17% by weight.
摘要翻译： 以管腔内置假体形式的植入物，其具有包含金属材料的管状体，任选地铁，由此在植入物主体的至少一部分中，与各自的浓度相比，以下存在于近表面边界层的结构中 在剩余结构中：增加的碳含量为约0.5重量％至约2重量％; 或增加的碳和氮含量，其中碳的浓度为约0.5重量％至约7重量％，氮的浓度为约0.5重量％至约17重量％。
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公开(公告)号：US09381100B2
公开(公告)日：2016-07-05
申请号：US13937113
申请日：2013-07-08
发明人： Ullrich Bayer , Bodo Gerold
IPC分类号： C23C8/20 , C23C8/22 , C23C8/24 , C23C8/26 , C23C8/30 , C23C8/32 , A61F2/82 , A61L31/02 , A61L31/08 , A61L31/14
CPC分类号： A61F2/82 , A61L31/022 , A61L31/084 , A61L31/148 , C23C8/20 , C23C8/22 , C23C8/24 , C23C8/26 , C23C8/30 , C23C8/32
摘要： Implant in the form of an intraluminal endoprosthesis, having a tubular body containing metallic material, optionally iron, whereby in at least a portion of the implant body the following are present in the structure of a near-surface boundary layer in comparison to the respective concentration in the remaining structure: an increased carbon content in a concentration of approximately 0.5% by weight to approximately 2% by weight; or an increased carbon and nitrogen content, wherein a concentration of carbon is approximately 0.5% by weight to approximately 7% by weight, and a concentration of nitrogen is approximately 0.5% by weight to approximately 17% by weight.
摘要翻译： 以管腔内置假体形式的植入物，其具有包含金属材料的管状体，任选地铁，由此在植入物主体的至少一部分中，与各自的浓度相比，以下存在于近表面边界层的结构中 在剩余结构中：增加的碳含量为约0.5重量％至约2重量％; 或增加的碳和氮含量，其中碳的浓度为约0.5重量％至约7重量％，氮的浓度为约0.5重量％至约17重量％。
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公开(公告)号：US20130304178A1
公开(公告)日：2013-11-14
申请号：US13937097
申请日：2013-07-08
发明人： Ullrich Bayer , Bodo Gerold
IPC分类号： A61F2/82
CPC分类号： A61F2/82 , A61L31/022 , A61L31/084 , A61L31/148 , C23C8/20 , C23C8/22 , C23C8/24 , C23C8/26 , C23C8/30 , C23C8/32
摘要： The present invention relates to a method for manufacturing an implant, in particular an intraluminal endoprosthesis, having a body containing metallic material, preferably iron. For controlling the degradation of the implant the method includes the following steps: (a) providing a first part of the implant body; and (b) performing heat treatment which alters the carbon content and/or the boron content and/or the nitrogen content in the structure of a near-surface boundary layer in the first part of the implant body in such a way that strain on the lattice or a lattice transformation, optionally following a subsequent mechanical load, is achieved in the near-surface boundary layer. Such an implant is also described.
摘要翻译： 本发明涉及用于制造植入物的方法，特别是管腔内假体，其具有包含金属材料，优选铁的主体。 为了控制植入物的降解，该方法包括以下步骤：（a）提供植入体的第一部分; 和（b）进行热处理，其改变植入物体的第一部分中的近表面边界层的结构中的碳含量和/或硼含量和/或氮含量，使得在 在近表面边界层中实现晶格或晶格转变，任选地遵循随后的机械负载。 还描述了这种植入物。
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