MICROWELL ARRAY CHIP, USE METHOD THEREFOR, AND DETECTION APPARATUS

    公开(公告)号:US20250033056A1

    公开(公告)日:2025-01-30

    申请号:US18713233

    申请日:2022-04-20

    Abstract: A microwell array chip, a use method therefor, and a detection apparatus. The microwell array chip includes a microwell array substrate, and the microwell array substrate includes n reaction chambers, and an idle region; an array of the n reaction chambers is disposed in the microwell array substrate, and the idle region is disposed around the n reaction chambers; each reaction chamber is configured to accommodate a sample to be tested, and the shape of an orthographic projection of the reaction chamber on a first reference plane where the first main surface is located is of a regular N-gon; the area of the idle region is divided into n′ virtual units, and the shape of the orthographic projection of each virtual unit on the first reference plane is the same as the shape of the orthographic projection of the reaction chamber on the first reference plane.

    CHIP PACKAGING STRUCTURE AND CHIP PACKAGING METHOD

    公开(公告)号:US20240351026A1

    公开(公告)日:2024-10-24

    申请号:US18039220

    申请日:2022-03-25

    Abstract: A chip packaging structure and a chip packaging method, the structure including: a sample substrate with through holes; first and second cover plates on opposite sides of the sample substrate; and at least one pair of a sample inlet and a sample outlet, each pair of the sample inlet and the sample outlet is in one or both of the first cover plate and the second cover plate, a flow path is between each pair of the sample inlet and the sample outlet, a first flow channel structure is on a surface of the first cover plate opposite to the sample substrate, a second flow channel structure is on a surface of the second cover plate opposite to the sample substrate, and the first flow channel structure and the second flow channel structure are connected with the through holes, to form a continuous channel corresponding to the flow path.

    DEVICE FOR DRIVING A CELL PROCESSING CHIP AND METHOD OF DRIVING A CELL PROCESSING CHIP

    公开(公告)号:US20230347339A1

    公开(公告)日:2023-11-02

    申请号:US17637334

    申请日:2021-04-27

    CPC classification number: B01L3/502715 B01L3/50273 B01L2300/0627

    Abstract: The present application discloses a device for driving a cell processing chip and a method of driving a cell processing chip. The cell processing chip is configured to process cells. The device for driving the cell processing chip includes a bearing member configured to carry the cell processing chip, an accommodating member in fluid communication with the cell processing chip, a fluid driving member configured to drive flow of fluid in the device and in the cell processing chip, a signal generating and processing member configured to apply a signal to a fluid in the cell processing chip to generate a response signal associated with the fluid, and configured to issue a control instruction, and a power supply configured to supply power to the fluid driving member, and configured to apply a sorting signal to the cell processing chip in response to the control instruction.

    MICROFLUIDIC CHIP AND DROPLET SEPARATION METHOD

    公开(公告)号:US20220168743A1

    公开(公告)日:2022-06-02

    申请号:US17355869

    申请日:2021-06-23

    Inventor: Ding DING Lin DENG

    Abstract: The present disclosure provides a microfluidic chip and a droplet separation method, and belongs to the field of biological chip technology. The microfluidic chip includes a first liquid tank and a second liquid tank opposite to each other and a channel layer therebetween. The channel layer includes a plurality of microfluidic channels separated from each other, first ends of the microfluidic channels are communicated with the first liquid tank, and second ends are communicated with the second liquid tank. The first liquid tank contains sample solution to be detected, and the second liquid tank contains encapsulating liquid. The sample solution to be detected entering the first liquid tank may be separated into a plurality of sample droplets through the microfluidic channels, the separated sample droplets enter the second liquid tank, so that the encapsulating liquid is encapsulated on a surface of each of the plurality of sample droplets.

    CHIP, MICROFLUIDIC DEVICE, AND METHOD FOR SORTING TARGET DROPLETS

    公开(公告)号:US20220339630A1

    公开(公告)日:2022-10-27

    申请号:US17731746

    申请日:2022-04-28

    Abstract: The present disclosure provides a chip, a microfluidic device including the chip, and a method for sorting target droplets. The chip includes a first container for accommodating a first fluid, a second container for accommodating a second fluid, a delivery channel including a first flow channel communicating with the first container and a second flow channel communicating with the second container, the first flow channel and the second flow channel intersecting and communicating with each other at a junction, and at least one collector. A portion of the first flow channel includes the junction and is divided into two sections by the junction, in each section, the section thickens gradually along a first direction away from the junction. The second flow channel includes the junction and is divided into two sections by the junction, in each section, the section thickens gradually along a second direction away from the junction.

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