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公开(公告)号：US20240293828A1
公开(公告)日：2024-09-05
申请号：US17996129
申请日：2021-10-22
发明人： Kang PENG , Zhukai LIU , Ding DING
CPC分类号： B04B7/08 , B01L3/502707 , B01L2400/0409
摘要： A centrifugal structure member of a microfluidic chip and a centrifuge are provided. The centrifugal structure member of a microfluidic chip includes: a connecting portion (10) configured to connect to a rotor of a centrifuge; a support portion (20) fixedly connected or integrally formed with the connecting portion (10), and having an inclined outer surface forming an included angle with the rotation axis (50) of the rotor of the centrifuge; and a mounting portion (30) connected with or formed on the inclined outer surface, and configured to detachably mount the microfluidic chip (40) on the support portion (20).
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公开(公告)号：US20240183848A1
公开(公告)日：2024-06-06
申请号：US17778177
申请日：2021-06-08
发明人： Haonan LIU , Ding DING
IPC分类号： G01N33/543 , B01L3/00
CPC分类号： G01N33/54386 , B01L3/502761 , B01L2200/16 , B01L2300/0816 , B01L2300/0867 , B01L2300/0883 , G01N2470/04
摘要： The present application discloses a first substrate for a microfluidic chip, the microfluidic chip, and a method for processing a sample. The first substrate includes a first injection port, a first reacting region, a first upstream end of which is communicated with the first injection port, a second injection port, a second reacting region, an upstream end of which is communicated with the second injection port, and a downstream end of which is communicated with a second upstream end of the first reacting region, a fluid backflow prevention region between the second reacting region and the first reacting region, an upstream end of which is communicated with the downstream end of the second reacting region, and a downstream end of which is communicated with the second upstream end of the first reacting region, and an exit port communicated with a downstream end of the first reacting region.
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公开(公告)号：US20240165619A1
公开(公告)日：2024-05-23
申请号：US17772647
申请日：2021-05-31
发明人： Zhukai LIU , Ding DING
IPC分类号： B01L3/00
CPC分类号： B01L3/502753 , B01L2300/0874 , B01L2300/1883
摘要： The present disclosure provide a detection chip having at least one functional region, the functional region including: a reaction region and a non-reaction region surrounding the reaction region. The detection chip includes: a first substrate and a second substrate opposite to each other. In the reaction region, a side of the first substrate facing the second substrate is provided with reaction grooves arranged in an array along a first direction and a second direction; first communication grooves each between two reaction grooves adjacent in the first direction, and connected with the two reaction grooves; and second communication grooves each between two first communication grooves adjacent in the second direction, and connected with the two adjacent first communication grooves, and the first direction intersects the second direction. The embodiments of the present disclosure further provide a fabrication method and a sample introduction method of the detection chip.
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公开(公告)号：US20240342724A1
公开(公告)日：2024-10-17
申请号：US18580314
申请日：2022-09-07
发明人： Houqian GAO , Zijian ZHAO , Ding DING , Shinying LAU
IPC分类号： B01L3/00
CPC分类号： B01L3/5085 , B01L2300/0893 , B01L2300/12 , B01L2300/161
摘要： A detection chip and a manufacturing method thereof, and a detection method are provided. The detection chip includes: a base substrate, and a detection layer, provided on the base substrate and including a plurality of detection holes. An inner wall of each of at least part of detection holes among the plurality of detection holes is hydrophilic, and a contact angle of the inner wall is within 30 degrees.
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公开(公告)号：US20240249997A1
公开(公告)日：2024-07-25
申请号：US18016411
申请日：2022-01-28
发明人： Beiyuan FAN , Ding DING
CPC分类号： H01L23/46 , B01L3/502761 , B01L2300/1811 , B01L2300/1838
摘要： A chip heat sink for a chip and a nucleic acid extraction device, where the chip has a channel for conveying a fluid, and on/off of the channel is controlled by an solenoid valve, the chip heat sink includes: a substrate, where the substrate has a first surface for placing the chip, and the first surface is provided with a first accommodating groove for accommodating an electromagnet; and a heat dissipation structure on the substrate and for dissipating heat from the electromagnet.
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公开(公告)号：US20240036036A1
公开(公告)日：2024-02-01
申请号：US17639078
申请日：2021-04-29
发明人： Haonan LIU , Xiangguo MA , Kai GENG , Ding DING
IPC分类号： G01N33/543 , B01L3/00 , G01N35/10
CPC分类号： G01N33/54306 , G01N33/54386 , B01L3/502761 , G01N35/10 , B01L2200/16 , B01L2200/0647 , B01L2300/027 , B01L2300/0636
摘要： An immunoassay device and an immunoassay method are provided. The immunoassay device includes: a housing, a driving assembly, a detection chip and a liquid storage chamber; the housing has a first accommodating part in which the detection chip is disposed and a second accommodating part in which the liquid storage chamber is disposed, and the liquid storage chamber is configured at least to store reagent; the driving assembly is configured to communicate a liquid outlet of the liquid storage chamber with a liquid inlet of the detection chip, and drive the reagent in the liquid storage chamber to enter the detection chip.
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7.发明公开公开(公告)号：US20230347339A1
公开(公告)日：2023-11-02
申请号：US17637334
申请日：2021-04-27
发明人： Lin DENG , Da LI , Fan YANG , Xiangguo MA , Ding DING
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/50273 , B01L2300/0627
摘要： The present application discloses a device for driving a cell processing chip and a method of driving a cell processing chip. The cell processing chip is configured to process cells. The device for driving the cell processing chip includes a bearing member configured to carry the cell processing chip, an accommodating member in fluid communication with the cell processing chip, a fluid driving member configured to drive flow of fluid in the device and in the cell processing chip, a signal generating and processing member configured to apply a signal to a fluid in the cell processing chip to generate a response signal associated with the fluid, and configured to issue a control instruction, and a power supply configured to supply power to the fluid driving member, and configured to apply a sorting signal to the cell processing chip in response to the control instruction.
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公开(公告)号：US20220410160A1
公开(公告)日：2022-12-29
申请号：US17780194
申请日：2021-06-09
发明人： Houqian GAO , Beiyuan FAN , Ding DING
IPC分类号： B01L3/00
摘要： The present disclosure provides a microfluidic chip including a plurality of microcavities, at least two of the plurality of microcavities have different volumes.
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公开(公告)号：US20240351026A1
公开(公告)日：2024-10-24
申请号：US18039220
申请日：2022-03-25
发明人： Xiangguo MA , Zhukai LIU , Ding DING , Lin DENG
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/5025 , B01L2200/027 , B01L2300/0829
摘要： A chip packaging structure and a chip packaging method, the structure including: a sample substrate with through holes; first and second cover plates on opposite sides of the sample substrate; and at least one pair of a sample inlet and a sample outlet, each pair of the sample inlet and the sample outlet is in one or both of the first cover plate and the second cover plate, a flow path is between each pair of the sample inlet and the sample outlet, a first flow channel structure is on a surface of the first cover plate opposite to the sample substrate, a second flow channel structure is on a surface of the second cover plate opposite to the sample substrate, and the first flow channel structure and the second flow channel structure are connected with the through holes, to form a continuous channel corresponding to the flow path.
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公开(公告)号：US20240170505A1
公开(公告)日：2024-05-23
申请号：US17777422
申请日：2021-05-31
发明人： Fanli MENG , Zeyuan LI , Jiangbo CHEN , Ding DING
IPC分类号： H01L27/144 , H01L23/31 , H01L27/092 , H01L27/12
CPC分类号： H01L27/1443 , H01L23/3171 , H01L27/0922 , H01L27/1259
摘要： The present disclosure relates to an X-RAY detector including a base substrate and a plurality of detection units arranged on the base substrate. Each detection unit includes a light conversion element and a switching transistor, the light conversion element is configured to convert an optical signal into an electrical signal, and the switching transistor is configured to output the electrical signal to a reading signal line. Each detection unit further includes a radiation shielding structure located at a light-entering side of the detection unit, and an orthogonal projection of the radiation shielding structure onto the base substrate fully covers an orthogonal projection of the switching transistor onto the base substrate. The present disclosure further relates to a method for forming the X-RAY detector.
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