-
公开(公告)号：US20220317116A1
公开(公告)日：2022-10-06
申请号：US17600301
申请日：2021-02-23
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Haonan LIU , Yudan YIN
IPC: G01N33/533
Abstract: A quality detection method of an immunochip is disclosed. At least part of a surface of the immunochip is a modified surface with modifying groups. The method comprises: applying a detection solution containing a labeled antibody on the modified surface of the immunochip, the labeled antibody is an antibody connected with a labeling substance, and the labeled antibody is capable of reacting with the modifying groups and bonding to the modifying groups; removing the labeled antibody that has not reacted with the modifying groups, and detecting the content of residual labeled antibody on the modified surface; and identifying the quality of the immunochip according to the content of residual labeled antibody.
-
公开(公告)号：US20210170407A1
公开(公告)日：2021-06-10
申请号：US17255981
申请日：2020-05-15
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Yudan YIN
IPC: B01L3/00 , B01L9/00 , G01N33/543
Abstract: The present disclosure provides a microfluidic chip, including: a support and an NFC coil in the support, and a flow path is provided in the support and is isolated from the NFC coil; the flow path includes at least one detection window region with a stationary phase therein, and the stationary phase is used to specifically capture a target analyte, the detection window region at least partially overlaps with the NFC coil in a thickness direction of the support. The present disclosure further provides a detection method of the microfluidic chip and a micro total analysis system. The present disclosure can quickly and immediately obtain a detection result.
-
公开(公告)号：US20220411732A1
公开(公告)日：2022-12-29
申请号：US17780251
申请日：2021-01-14
Applicant: BOE Technology Group Co., Ltd.
Inventor： Mengjun HOU , Zijian ZHAO , Yudan YIN , Zongmin LIU , Liye DUAN
IPC: C12M1/34
Abstract: Disclosed are a detection chip and a manufacturing method therefor, and a reaction system. The detection chip includes: a first substrate (11); a microcavity defining layer (12), which is located on the first substrate (11) and defines a plurality of micro-reaction chambers (120); and a shading structure layer (13), which is located on the first substrate (11) and provided among the plurality of micro-reaction chambers (120). In practical application, the number of target molecules in a reaction system solution in each micro-reaction chamber (120) can be determined by collecting a fluorescence image; and the detection chip is provided with the shading structure layer (13), and the shading structure layer (13) is located on the first substrate (11) and provided among the plurality of micro-reaction chambers (120).
-
4.发明申请公开(公告)号：US20210206808A1
公开(公告)日：2021-07-08
申请号：US16646320
申请日：2019-08-22
Inventor： Zijian ZHAO , Yudan YIN
IPC: C07K14/00 , G01N33/574 , C07K1/04 , C07K1/08 , G01N21/64
Abstract: A peptoid compound, a manufacturing method of a peptoid compound, an oligomer, a pharmaceutical composition, use of the pharmaceutical composition in the preparation of a medicament for detecting or diagnosing a disease related to tyrosine kinase HER2, and a kit for identifying circulating tumor cells are provided, the peptoid compound includes: a cysteine (Cys) subunit, a butanediamine (Nlys) subunit, a 3,4-methylenedioxybenzylamine (Npip) subunit, a 3-aminopropanic acid (Nce) subunit and a 1-naphthylamine (Na) subunit, and both the peptoid compound and the oligomer have a strong ability to bind to HER2 protein on surfaces of circulating tumor cells (CTCs), and a technology of diagnosing breast cancer on the basis of the peptoid compound can realize non-invasive and label-free rapid diagnosis, in addition, the methods for synthesizing the peptoid compound and the oligomer are simple, the preparation efficiency is high, and the production cost is low.
-
公开(公告)号：US20230176045A1
公开(公告)日：2023-06-08
申请号：US17928663
申请日：2021-05-12
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
IPC: G01N33/543 , G01N21/64 , B01L3/00
CPC classification number: G01N33/54386 , G01N21/6458 , G01N21/6428 , B01L3/502761 , G01N2021/6439 , B01L2400/084 , B01L2300/0654 , B01L2200/0647 , B01L2200/16
Abstract: The present disclosure provides microfluidic flow channel structure, detection system and method for using detection system, aiming at improving uniformity of liquid introduction of microfluidic detection system. Microfluidic flow channel structure includes liquid inlet section (1), main chamber (3) and liquid outlet section (2), main chamber (3) includes liquid inlet end (31), chamber middle part (33) and liquid outlet end (32); liquid inlet section (1), liquid inlet end (31), chamber middle part (33), liquid outlet end (32) and liquid outlet section (2) are sequentially connected together; width of liquid inlet end (31) is gradually increased in direction from liquid inlet section (1) to chamber middle part (33); thinning flow guidance region (310) is provided at edge of liquid inlet end (31) formed as width of liquid inlet end varies, and has thickness less than that of remaining region except thinning flow guidance region (310) of main chamber (3).
-
Patent Agency Ranking
公开(公告)号：US20220274106A1
公开(公告)日：2022-09-01
申请号：US17631461
申请日：2021-03-03
Applicant: BOE Technology Group Co., Ltd.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
Abstract: Disclosed are a detection chip and a modification method therefor. A surface activation treatment is performed on a hydrophilic layer of the detection chip, such that a hydroxy-containing modification group is formed on a surface of the hydrophilic layer; and a solution containing an oxy compound is then used to perform a surface epoxidation treatment on the hydrophilic layer in order to form an epoxy-containing modification group on the surface of the hydrophilic layer.
-
公开(公告)号：US20210268504A1
公开(公告)日：2021-09-02
申请号：US17254984
申请日：2020-03-31
Inventor： Zijian ZHAO , Mengjun HOU , Yudan YIN
Abstract: A reaction device for a detection chip and a reaction system are provided. The reaction device includes a chip carrier and an electrical signal control unit. The chip carrier is configured to place and fix the detection chip; and the electrical signal control unit is configured to apply an electrical signal to the detection chip so as to drive a heating electrode of the detection chip.
-
公开(公告)号：US20220274107A1
公开(公告)日：2022-09-01
申请号：US17631463
申请日：2021-03-04
Applicant: BOE Technology Group Co., Ltd.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
Abstract: Disclosed are a detection chip and a modification method therefor. The method for modifying the detection chip comprises performing a surface film-forming treatment on a hydrophilic layer on a first substrate constituting the detection chip to form polydopamine film on a surface of the hydrophilic layer; and adopting a buffer solution containing sodium hyaluronate to perform a surface carboxylation treatment on the hydrophilic layer, on the surface of which the polydopamine film has been formed, in order to form a carboxyl-containing modification group on the surface of the hydrophilic layer.
-
公开(公告)号：US20220274105A1
公开(公告)日：2022-09-01
申请号：US17631460
申请日：2021-03-03
Applicant: BOE Technology Group Co., Ltd.
Inventor： Yudan YIN , Jing YU , Haonan LIU , Zhukai LIU
Abstract: Disclosed are a detection chip and a modification method therefor. The modification method includes performing a surface activation treatment on a hydrophilic layer of the detection chip, such that a hydroxy-containing modification group is formed on a surface of the hydrophilic layer; then performing a surface amination treatment on the hydrophilic layer using a solution containing an amino compound, such that an amino-containing modification group is formed on the surface of the hydrophilic layer, and performing a surface carboxylation treatment on the hydrophilic layer using a solution containing an anhydride compound, such that a carboxyl-containing modification group is formed on the surface of the hydrophilic layer.
-
公开(公告)号：US20220258163A1
公开(公告)日：2022-08-18
申请号：US17736817
申请日：2022-05-04
Applicant: BOE TECHNOLOGY GROUP CO., LTD.
Inventor： Zhihong WU , Defeng MAO , Zijian ZHAO , Yudan YIN
Abstract: A microfluidic particle sorting apparatus for capturing targets from fluid containing the targets is disclosed. The apparatus includes an inlet for receiving the fluid; a sorting chamber allowing the fluid to flow through; a first outlet for discharging the fluid after flowing through the sorting chamber; a capturing structure for capturing the cells, wherein the capturing structure is upstream of the first outlet, and includes obstacles in an array, each extending through the sorting chamber in a lateral direction with respect to a fluid flow of the fluid; and a second outlet upstream of the capturing structure comprising a plurality of openings; wherein a gap between two adjacent obstacles is equal to or greater than each opening of the second outlet.
-
-
-
-
-
-
-
-
-
Search Results
17
records
(took 0.017 seconds)
