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公开(公告)号：US20220364964A1
公开(公告)日：2022-11-17
申请号：US17619297
申请日：2020-06-09
发明人： Lijiao HU , Haochen CUI , Chungen YUAN
摘要： A sampling structure, a sealing structure and a detection assembly are provided. The sampling structure includes a first main body, a second main body and a third main body. The first main body includes a first channel, the first channel includes a first opening that is exposed. The second main body is connected to the first main body and includes a second channel and at least one partition column located in the second channel, the second channel is linked with the first channel, and a first gap is between the partition column and a channel wall of the second channel. The third main body is connected to the second main body and includes a chamber, the chamber is linked with the second channel and is capable of containing a sample.
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公开(公告)号：US20220226824A1
公开(公告)日：2022-07-21
申请号：US17614601
申请日：2021-02-01
发明人： Lijiao HU , Haochen CUI , Xiaohe SHEN , Chungen YUAN , Tao HU , Jing LI , Weiqiong GAN
IPC分类号： B01L3/00
摘要： A detection chip, a method for using a detection chip and a detection apparatus are provided the detection chip includes a chip substrate and the chip substrate includes a fluid channel and a plurality of liquid cells. The fluid channel is arranged on a surface if the chip substrate and includes a main path and a plurality of branch paths. The plurality of branch paths are respectively communicated to the plurality of liquid cells, the plurality of branch paths are all communicated to the main path, and communication points between the plurality of branch paths and the main path are different. The plurality of branch paths are configured to allow liquid in the plurality of branch paths to be capable of merging into the main path in a same direction.
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公开(公告)号：US20220226818A1
公开(公告)日：2022-07-21
申请号：US17609816
申请日：2021-01-15
发明人： Haochen CUI , Jing LI , Tao HU , Lijiao HU , Chungen YUAN , Xiaohe SHEN
IPC分类号： B01L3/00
摘要： A detection chip and a detection system are provided. The detection chip includes a base substrate, a flow channel defining layer, and at least one driving electrode group. The at least driving electrode group is on the base substrate, and the flow channel defining layer is on a side of the at least one driving electrode group away from the base substrate, the flow channel defining laver includes a flow channel structure, and the flow channel structure is configured to accommodate liquid; and each of the at least one driving electrode group includes a plurality of driving electrodes, and the plurality of driving electrodes are configured to contact the liquid and drive the liquid to move within the flow channel structure.
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公开(公告)号：US20220250067A1
公开(公告)日：2022-08-11
申请号：US17622277
申请日：2021-02-01
发明人： Lijiao HU , Haochen CUI , Chungen YUAN , Tao HU , Jing LI , Weiqiong GAN , Xiaohe SHEN
IPC分类号： B01L3/00
摘要： A detection chip, a method for using a dejection chip, and a detection device are provided. The detection chip includes a chip substrate and a first sealing film that are stacked. The chip substrate includes a first surface, and the first sealing film covers the first surface of the chip substrate The chip substrate further includes a fluid channel on the first surface, and the fluid channel includes a plurality of membrane valve portions. The membrane valve portions are configured to allow a portion of fee first sealing film covering the membrane valve portions to approach and separate, so as to close and open the fluid channel correspondingly.
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公开(公告)号：US20230022752A1
公开(公告)日：2023-01-26
申请号：US17041544
申请日：2019-11-13
发明人： Xiaohe SHEN , Chungen YUAN , Haochen CUI , Lijiao Hu , Tao HU , Jing LI , Weiqiong GAN
IPC分类号： B01L3/00
摘要： A detection chip is disclosed. The detection chip includes a sample injection structure, a filter structure, and a reaction structure which are sequentially connected. The filter structure includes a first main body, and a first inlet portion and a first outlet portion respectively on two sides of the first main body. A width of the first inlet portion gradually decreases in a direction away from the first main body, and a width of the first outlet portion gradually decreases in a direction away from the first main body.
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公开(公告)号：US20210220828A1
公开(公告)日：2021-07-22
申请号：US16631984
申请日：2019-01-15
发明人： Haochen CUI , Wenliang YAO , Peizhi CAI , Chuncheng CHE , Yingying ZHAO , Yuelei XIAO , Le GU , Yue GENG , Nan ZHAO , Hui LIAO , Fengchun PANG
IPC分类号： B01L3/00
摘要： A biological detection substrate, a microfluidic chip and a driving method thereof, and a microfluidic detection component are provided. The biological detection substrate includes a sample capture region, the sample capture region includes an electromagnetic coil, and the electromagnetic coil is configured to capture a sample in a sample droplet that is driven to pass through the sample capture region.
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公开(公告)号：US20210060555A1
公开(公告)日：2021-03-04
申请号：US16632931
申请日：2019-01-02
发明人： Wenliang YAO , Haochen CUI , Peizhi CAI , Yuelei XIAO , Fengchun PANG , Yue GENG , Le GU , Nan ZHAO , Hui LIAO , Yingying ZHAO , Chuncheng CHE
IPC分类号： B01L3/00
摘要： A microfluidic device, a microfluidic detection assembly and a detection method for the microfluidic device. The microfluidic device includes a first substrate and a second substrate; the first substrate and the second substrate are oppositely arranged to define a channel between the first substrate and the second substrate, the channel is configured for liquid to flow, the first substrate includes a base substrate and a plurality of control assemblies which are arranged on the base substrate along an extending direction of the channel, each of the plurality of control assemblies includes: a first electrode, a second electrode and a plurality of coils, and the first electrode is configured to input currents into the plurality of coils, and the plurality of coils are connected in parallel to the second electrode.
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公开(公告)号：US20210322986A1
公开(公告)日：2021-10-21
申请号：US17273173
申请日：2020-07-03
发明人： Wenliang YAO , Peizhi CAI , Yingying ZHAO , Le GU , Nan ZHAO , Haochen CUI
摘要： The present disclosure provides a PCR substrate, a PCR chip, a PCR system, and a liquid droplets pull-out method. The PCR substrate includes a first base; a driving structure disposed on the first base and configured to drive liquid droplets to move; where the first base includes an injection region, a stretching region and an amplification region, and the driving structure is configured to enable liquid in the injection region to form liquid droplets in the stretching region and enable the liquid droplets to move in the amplification region according to a predetermined track.
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公开(公告)号：US20200338549A1
公开(公告)日：2020-10-29
申请号：US16768558
申请日：2019-11-13
发明人： Yingying ZHAO , Peizhi CAI , Le GU , Fengchun PANG , Yue GENG , Yuelei XIAO , Haochen CUI , Nan ZHAO , Hui LIAO , Wenliang YAO , Chuncheng CHE
IPC分类号： B01L3/00
摘要： The present disclosure provides a microfluidic chip, including: first base substrate and a second base substrate opposite to each other; first electrode and second electrode between the first base substrate and the second base substrate and configured to control droplet to move between the first base substrate and the second base substrate according to voltages applied on the first electrode and the second electrode; light guide component configured to guide light propagating in the first base substrate to the droplet; shading component and detection component, shading component having light transmission regions spaced from each other, light transmission regions being configured to transmit light passing through the droplet to the detection component, wherein detection component is on second base substrate and is configured to obtain property of the droplet according to an intensity of the light passing through droplet and received from the light transmission regions.
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公开(公告)号：US20220023865A1
公开(公告)日：2022-01-27
申请号：US16631780
申请日：2019-05-13
发明人： Le GU , Peizhi CAI , Fengchun PANG , Yue GENG , Yingying ZHAO , Haochen CUI , Yuelei XIAO , Hui LIAO , Wenliang YAO , Nan ZHAO
摘要： A microfluidic device and a detection method for the microfluidic device are provided. The microfluidic device includes a driving substrate configured to drive a movement of a droplet; and a position detector configured to detect a position of the droplet on the driving substrate.
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