公开(公告)号：US20150282859A1

公开(公告)日：2015-10-08

申请号：US14747702

申请日：2015-06-23

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： ROBERT F. BENCINI ,  FRANK INGLE ,  JOSEF V. KOBLISH ,  REBECCA TIN ,  JAMES MAZZONE ,  BYRON CHUN ,  DAVID LAWRENCE

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B5/0422 ,  A61B2018/00017 ,  A61B2018/00023 ,  A61B2018/0022 ,  A61B2018/00714 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/0212 ,  A61B2018/0262

Abstract: In some implementations, a method of ablating body tissue includes (a) locating an inflatable balloon portion of a cryotherapy balloon catheter at a treatment site internal to a patient's body, and inflating the inflatable balloon portion; (b) employing electrodes that are disposed on an expandable surface of the inflatable balloon portion to electrically characterize body tissue at the treatment site; (c) ablating the body tissue by supplying a cryotherapy agent to the inflatable balloon portion to cool the body tissue to a therapeutic temperature; (d) employing the electrodes to determine whether the ablating caused desired electrical changes in the body tissue; and (e) repeating (c) and (d) when it is determined that the ablating did not cause the desired electrical changes.

Abstract translation: 在一些实施方案中，消融身体组织的方法包括（a）将冷冻治疗气囊导管的可充气球囊部分定位在患者身体内部的治疗部位处，并使可膨胀气囊部分膨胀; （b）使用设置在所述可膨胀气囊部分的可膨胀表面上的电极来电性地表征所述治疗部位的身体组织; （c）通过向所述可充气球囊部分供应冷冻治疗剂来将所述身体组织冷却至治疗温度来烧蚀所述身体组织; （d）使用电极来确定烧蚀是否引起人体组织中所需的电变化; 和（e）重复（c）和（d）当确定烧蚀不引起所需的电气变化时。

公开(公告)号：US20150250525A1

公开(公告)日：2015-09-10

申请号：US14712405

申请日：2015-05-14

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： FRANK INGLE ,  REBECCA TIN ,  ROBERT F. BENCINI ,  JAMES MAZZONE

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B2018/00255 ,  A61B2018/0212

Abstract: A cryotherapy system includes a cryotherapy catheter having an inflatable balloon portion and a pressure regulator. The inflatable balloon portion includes an outer balloon and an inner balloon within the outer balloon. The inner balloon is configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue at a desired location. The inflatable balloon portion is at a distal end of the cryotherapy catheter. The pressure regulator is adapted to maintain a positive pressure between the inner balloon and the outer balloon during a cryotherapy procedure.

Abstract translation: 冷冻治疗系统包括具有可充气球囊部分和压力调节器的冷冻治疗导管。 可膨胀气囊部分包括外球囊和外球囊内的内球囊。 内部气囊被配置为在冷冻治疗过程期间接收用于在期望位置从身体组织提取热量的低温剂。 可膨胀气囊部分在冷冻治疗导管的远端。 压力调节器适于在冷冻治疗过程期间在内部球囊和外部球囊之间保持​​正压力。

公开(公告)号：US20130281996A1

公开(公告)日：2013-10-24

申请号：US13926853

申请日：2013-06-25

Applicant: Boston Scientific Scimed, Inc.

Inventor： FRANK INGLE ,  RAPHAEL HON

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262

Abstract: Apparatus and methods for uniformly distributing coolant within a cryo-ablation device. A nozzle apparatus includes a tubular member having a plurality of angled apertures that induce swirling of coolant streams dispersed through the angled apertures. Coolant swirling round the tubular member and along an inner surface of an inflatable balloon element inflates the balloon element and cryogenically ablate tissue. The swirling action achieved using angled apertures uniformly distributes coolant along the inner surface of the balloon such that the temperatures along an inner surface of the balloon element and ablation of tissue adjacent to the balloon element are substantially uniform.