公开(公告)号：US20150282859A1

公开(公告)日：2015-10-08

申请号：US14747702

申请日：2015-06-23

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： ROBERT F. BENCINI ,  FRANK INGLE ,  JOSEF V. KOBLISH ,  REBECCA TIN ,  JAMES MAZZONE ,  BYRON CHUN ,  DAVID LAWRENCE

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B5/0422 ,  A61B2018/00017 ,  A61B2018/00023 ,  A61B2018/0022 ,  A61B2018/00714 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/0212 ,  A61B2018/0262

Abstract: In some implementations, a method of ablating body tissue includes (a) locating an inflatable balloon portion of a cryotherapy balloon catheter at a treatment site internal to a patient's body, and inflating the inflatable balloon portion; (b) employing electrodes that are disposed on an expandable surface of the inflatable balloon portion to electrically characterize body tissue at the treatment site; (c) ablating the body tissue by supplying a cryotherapy agent to the inflatable balloon portion to cool the body tissue to a therapeutic temperature; (d) employing the electrodes to determine whether the ablating caused desired electrical changes in the body tissue; and (e) repeating (c) and (d) when it is determined that the ablating did not cause the desired electrical changes.

Abstract translation: 在一些实施方案中，消融身体组织的方法包括（a）将冷冻治疗气囊导管的可充气球囊部分定位在患者身体内部的治疗部位处，并使可膨胀气囊部分膨胀; （b）使用设置在所述可膨胀气囊部分的可膨胀表面上的电极来电性地表征所述治疗部位的身体组织; （c）通过向所述可充气球囊部分供应冷冻治疗剂来将所述身体组织冷却至治疗温度来烧蚀所述身体组织; （d）使用电极来确定烧蚀是否引起人体组织中所需的电变化; 和（e）重复（c）和（d）当确定烧蚀不引起所需的电气变化时。

公开(公告)号：US20130289550A1

公开(公告)日：2013-10-31

申请号：US13938086

申请日：2013-07-09

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： FRANK W. INGLE ,  ROBERT F. BENCINI ,  JOSEF V. KOBLISH ,  JONATHAN A. WOHLGEMUTH ,  PAUL A. ROCHE

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2018/00196 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/1011

Abstract: Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.

公开(公告)号：US20150250525A1

公开(公告)日：2015-09-10

申请号：US14712405

申请日：2015-05-14

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： FRANK INGLE ,  REBECCA TIN ,  ROBERT F. BENCINI ,  JAMES MAZZONE

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B2018/00255 ,  A61B2018/0212

Abstract: A cryotherapy system includes a cryotherapy catheter having an inflatable balloon portion and a pressure regulator. The inflatable balloon portion includes an outer balloon and an inner balloon within the outer balloon. The inner balloon is configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue at a desired location. The inflatable balloon portion is at a distal end of the cryotherapy catheter. The pressure regulator is adapted to maintain a positive pressure between the inner balloon and the outer balloon during a cryotherapy procedure.

Abstract translation: 冷冻治疗系统包括具有可充气球囊部分和压力调节器的冷冻治疗导管。 可膨胀气囊部分包括外球囊和外球囊内的内球囊。 内部气囊被配置为在冷冻治疗过程期间接收用于在期望位置从身体组织提取热量的低温剂。 可膨胀气囊部分在冷冻治疗导管的远端。 压力调节器适于在冷冻治疗过程期间在内部球囊和外部球囊之间保持​​正压力。

公开(公告)号：US20150342672A1

公开(公告)日：2015-12-03

申请号：US14716405

申请日：2015-05-19

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： ROBERT F. BENCINI ,  JOSEF V. KOBLISH

IPC: A61B18/14 ,  A61B5/00 ,  A61B8/12 ,  A61B5/042 ,  A61B5/01

CPC classification number: A61B5/6852 ,  A61B5/01 ,  A61B5/0422 ,  A61B8/12 ,  A61B18/1492 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00773 ,  A61B2018/00791 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2562/0247 ,  A61B2562/0271 ,  A61B2562/04

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter for use in cardiac mapping and/or ablation. The catheter may include an elongate catheter shaft having a distal ablation electrode region capable of ablating tissue. A plurality of micro-electrode assemblies may be coupled to the distal ablation electrode region. At least one of the micro-electrode assemblies may include an inner electrode and an outer electrode disposed at least partially around the inner electrode. At least one of the inner electrode and the outer electrode may comprise a sensor.

Abstract translation: 公开了用于制造和使用医疗装置的医疗装置和方法。 示例性医疗装置可以包括用于心脏图谱和/或消融的导管。 导管可以包括细长导管轴，其具有能够消融组织的远端消融电极区域。 多个微电极组件可以联接到远端消融电极区域。 微电极组件中的至少一个可以包括至少部分地围绕内部电极设置的内部电极和外部电极。 内部电极和外部电极中的至少一个可以包括传感器。

公开(公告)号：US20150148796A1

公开(公告)日：2015-05-28

申请号：US14613155

申请日：2015-02-03

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： ROBERT F. BENCINI

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B2017/00084 ,  A61B2017/00526 ,  A61B2018/00011 ,  A61B2018/00101 ,  A61B2018/00214 ,  A61B2018/00577 ,  A61B2018/00791 ,  Y10T29/49002

Abstract: Disclosed herein is a catheter device sized and shaped for vascular access that has an elongate body extending between a proximal end and a distal end. Further, the elongate body has at least one inner lumen configured to receive a fluid. The catheter also has an ablation electrode configured to provide ablative energy, wherein the electrode is located distally along the elongate body and includes a passageway fluidly connected to the lumen of the elongate body. Also, the catheter has a sensor configured to provide a signal representative of temperature, and an insulating chamber extending at least partially about the ablation electrode and configured to at least partially insulate the sensor.

Abstract translation: 本文公开了一种导管装置，其尺寸和形状用于血管通路，其具有在近端和远端之间延伸的细长主体。 此外，细长体具有构造成接收流体的至少一个内腔。 导管还具有被配置为提供烧蚀能量的消融电极，其中电极沿着细长体向远侧定位，并且包括流体连接到细长体的内腔的通道。 此外，导管具有构造成提供表示温度的信号的传感器，以及绝缘室，其至少部分地围绕消融电极延伸并且被配置为至少部分地使传感器绝缘。