公开(公告)号：US20160296217A1

公开(公告)日：2016-10-13

申请号：US15155589

申请日：2016-05-16

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Tracee E.J. Eichenschink ,  Liliana Atanasoska ,  Jan Weber

IPC: A61B17/00

CPC classification number: A61B17/0057 ,  A61B17/12022 ,  A61B17/12159 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/1219 ,  A61B2017/00778 ,  A61B2017/00867 ,  A61B2017/00871 ,  A61F2/07 ,  A61F2/91 ,  A61F2250/0023

Abstract: A device for sealing a puncture opening may include a base frame having a delivery configuration wherein the base frame is retracted to have a relatively smaller overall profile, and a deployed configuration wherein the base frame is extended to have a relatively larger overall profile. The base frame is sized to engage an interior surface of the blood vessel wall in the deployed configuration. A sealing section is coupled to the base frame, the sealing section having an initial configuration wherein the sealing section permits fluid flow, and a barrier configuration wherein the sealing section prevents fluid flow. The sealing section in the barrier configuration is sized to block fluid flow through the puncture opening when the base frame is in the deployed configuration.

Abstract translation: 用于密封穿刺开口的装置可以包括具有输送构型的基座框架，其中底架缩回以具有相对较小的总体轮廓，以及展开构型，其中底架被延伸以具有相对较大的整体轮廓。 基座的尺寸设计成在展开构型中接合血管壁的内表面。 密封部分联接到基部框架，密封部分具有初始构造，其中密封部分允许流体流动，以及阻挡构造，其中密封部分防止流体流动。 阻挡构造中的密封部分的尺寸被设计成当底架处于展开构型时阻止穿过穿刺孔的流体流动。

公开(公告)号：US10376254B2

公开(公告)日：2019-08-13

申请号：US15155589

申请日：2016-05-16

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Tracee E. J. Eichenschink ,  Liliana Atanasoska ,  Jan Weber

IPC: A61B17/00 ,  A61B17/12 ,  A61F2/07 ,  A61F2/91

Abstract: A device for sealing a puncture opening may include a base frame having a delivery configuration wherein the base frame is retracted to have a relatively smaller overall profile, and a deployed configuration wherein the base frame is extended to have a relatively larger overall profile. The base frame is sized to engage an interior surface of the blood vessel wall in the deployed configuration. A sealing section is coupled to the base frame, the sealing section having an initial configuration wherein the sealing section permits fluid flow, and a barrier configuration wherein the sealing section prevents fluid flow. The sealing section in the barrier configuration is sized to block fluid flow through the puncture opening when the base frame is in the deployed configuration.

公开(公告)号：US20140242141A1

公开(公告)日：2014-08-28

申请号：US14271737

申请日：2014-05-07

Applicant: Boston Scientific Scimed, Inc.

Inventor： Liliana Atanasoska ,  Jan Weber ,  Robert W. Warner

IPC: A61L31/12 ,  A61L27/44

CPC classification number: A61L31/128 ,  A61L27/34 ,  A61L27/446 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L2300/608 ,  A61L2420/04 ,  Y10T428/1321 ,  Y10T428/1334 ,  Y10T428/1341 ,  Y10T428/1355 ,  Y10T428/1372 ,  Y10T428/1386 ,  Y10T428/1393 ,  Y10T428/31511 ,  Y10T428/31663 ,  Y10T428/31692 ,  Y10T428/31855

Abstract: In one aspect, the present invention provides composite coatings for implantable or insertable medical devices. These composite coatings comprise (a) an inorganic portion and (b) a polymeric portion that comprises a poly(vinyl pyrrolidone) (PVP) block.

Abstract translation: 一方面，本发明提供了用于可植入或可插入的医疗装置的复合涂层。 这些复合涂层包括（a）无机部分和（b）包含聚（乙烯基吡咯烷酮）（PVP）嵌段的聚合物部分。

公开(公告)号：US20130251778A1

公开(公告)日：2013-09-26

申请号：US13892720

申请日：2013-05-13

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Michael S. Arney ,  Robert W. Warner ,  Liliana Atanasoska

IPC: A61L27/34 ,  A61L27/54

CPC classification number: A61L27/34 ,  A61F2250/0067 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/604

Abstract: Implantable or insertable medical devices are described, which include one or more polymeric regions and one or more therapeutic agents. The polymeric regions, which regulate the release of one or more therapeutic agent from the medical device, contain copolymer molecules, each of which includes one or more soft segments and one or more uniform hard segments (e.g., polyamide segments that do not vary in length from molecule to molecule, among others).

Abstract translation: 描述了可植入或可插入的医疗装置，其包括一个或多个聚合物区域和一种或多种治疗剂。 调节一种或多种治疗剂从医疗装置释放的聚合物区域含有共聚物分子，每一种共聚物分子包括一个或多个软链段和一个或多个均匀的硬链段（例如，长度不变的聚酰胺链段 从分子到分子等）。