专利检索 ap:("BRISTOL-MYERS SQUIBB COMPANY") AND inv:"YAM B. POUDEL" 第 1 页

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发明申请
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS AND METHODS AND USES THEREFOR 有权

公开(公告)号：US20230140047A1

公开(公告)日：2023-05-04

申请号：US18081558

申请日：2022-12-14

申请人： BRISTOL-MYERS SQUIBB COMPANY

发明人： YAM B. POUDEL , Sanjeev GANGWAR , Liqi HE , Prasanna SIVAPRAKASAM , Matthias BROEKEMA , Matthew COX , Christine M. TARBY , Qian ZHANG , Naidu S. CHOWDARI

IPC分类号： A61K31/519 , A61K47/60 , A61K39/395 , C07D487/04 , A61P35/00 , A61K31/395

摘要： Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.