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公开(公告)号:US08227431B2
公开(公告)日:2012-07-24
申请号:US12402601
申请日:2009-03-12
申请人: Bandi Parthasaradhi Reddy , Vedula Manohar Sharma , Kura Rathnakar Reddy , Musku Madhanmohan Reddy , Jennepalli Sreenu , Aryasomayajula Ratnakar
发明人: Bandi Parthasaradhi Reddy , Vedula Manohar Sharma , Kura Rathnakar Reddy , Musku Madhanmohan Reddy , Jennepalli Sreenu , Aryasomayajula Ratnakar
CPC分类号: C07H19/173 , A61K31/7042 , A61K31/7076
摘要: The present patent application relates to the novel nucleoside derivatives and novel intermediates, which are useful to antiviral, anti tumor and immunomodulatory activity, method of treating diseases, conditions and/or disorders modulated by viral infections with them, and processes for preparing them.
摘要翻译: 本专利申请涉及可用于抗病毒,抗肿瘤和免疫调节活性的新型核苷衍生物和新型中间体,用于治疗由病毒感染调节的疾病,病症和/或病症的方法及其制备方法。
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公开(公告)号:US20140221328A1
公开(公告)日:2014-08-07
申请号:US13979045
申请日:2011-09-22
申请人: Bandi Parthasaradhi Reddy , Vedula Manohar Sharma , Kura Rathnakar Reddy , Musku Madhanmohan Reddy
发明人: Bandi Parthasaradhi Reddy , Vedula Manohar Sharma , Kura Rathnakar Reddy , Musku Madhanmohan Reddy
IPC分类号: C07J53/00
CPC分类号: C07J53/002 , C07J63/008
摘要: The present invention relates to certain novel salts of Betulinic acid derivatives, to process for preparing such compounds, to use the compounds in treating diseases or disorders mediated by HIV infection, to methods for their therapeutic use and to pharmaceutical compositions containing them.
摘要翻译: 本发明涉及某些桦木酸衍生物的新型盐,用于制备这些化合物的方法,以使用该化合物治疗由HIV感染介导的疾病或病症,其治疗用途的方法和含有它们的药物组合物。
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公开(公告)号:US09067966B2
公开(公告)日:2015-06-30
申请号:US12829483
申请日:2010-07-02
申请人: Bandi Parthasaradhi Reddy , Vedula Manohar Sharma , Kura Rathnakar Reddy , Musku Madhanmohan Reddy , Nelli Yella Reddy , Lanka VL Subrahmanyam
发明人: Bandi Parthasaradhi Reddy , Vedula Manohar Sharma , Kura Rathnakar Reddy , Musku Madhanmohan Reddy , Nelli Yella Reddy , Lanka VL Subrahmanyam
CPC分类号: C07J63/008 , C07J69/00
摘要: The invention relates to novel lupeol-type triterpene derivatives and related compounds, and pharmaceutical compositions useful for therapeutic treatment of viral diseases and particularly HIV mediated diseases.
摘要翻译: 本发明涉及新型的lupeol型三萜衍生物和相关化合物,以及可用于治疗性治疗病毒性疾病,特别是HIV介导的疾病的药物组合物。
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公开(公告)号:US08802727B2
公开(公告)日:2014-08-12
申请号:US12987228
申请日:2011-01-10
申请人: Bandi Parthasaradhi Reddy , Vedula Manohar Sharma , Kura Rathnakar Reddy , Musku Madhanmohan Reddy
发明人: Bandi Parthasaradhi Reddy , Vedula Manohar Sharma , Kura Rathnakar Reddy , Musku Madhanmohan Reddy
CPC分类号: C07J63/008 , A61K31/215 , A61K31/40 , A61K31/4453 , A61K31/496 , C07C69/753 , C07D295/16 , C07D401/02 , C07D401/14
摘要: The present invention relates to certain novel salts of Betulinic acid derivatives, to process for preparing such compounds, to use the compounds in treating diseases or disorders mediated by HIV infection, to methods for their therapeutic use and to pharmaceutical compositions containing them.
摘要翻译: 本发明涉及某些桦木酸衍生物的新型盐,用于制备这些化合物的方法,使用该化合物治疗由HIV感染介导的疾病或病症,其治疗用途的方法和含有它们的药物组合物。
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公开(公告)号:US20110212990A1
公开(公告)日:2011-09-01
申请号:US12678793
申请日:2008-11-06
申请人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Rapolu Raji Reddy , Dasari Muralidhara Reddy , Musku Madhanmohan Reddy , Deevireddy Bharath Reddy
发明人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Rapolu Raji Reddy , Dasari Muralidhara Reddy , Musku Madhanmohan Reddy , Deevireddy Bharath Reddy
IPC分类号: A61K31/437 , C07D471/04 , A61P31/00
CPC分类号: C07D471/04
摘要: The present invention relates to novel polymorph of moxifloxacin hydrochloride, processes for its preparation and to pharmaceutical compositions containing it. Thus, for example moxifloxacin hydrochloride is suspended in methanol and water and the pH is adjusted to 1.0-2.0 with concentrated hydrochloric acid at 25° C. and the separated solid is collected and dried to obtain moxifloxacin hydrochloride monohydrate polymorph IV.
摘要翻译: 本发明涉及盐酸莫西沙星的新型多晶型物,其制备方法和含有它的药物组合物。 因此,例如将莫西沙星盐酸盐悬浮于甲醇和水中,用浓盐酸在25℃将pH调节至1.0-2.0,收集分离的固体并干燥,得到盐酸莫西沙星一水合物多晶型IV。
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公开(公告)号:US09150547B2
公开(公告)日:2015-10-06
申请号:US13989541
申请日:2011-11-11
申请人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Thungathurthy Srinivasa Rao , Bandi Vamsi Krishna
发明人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Thungathurthy Srinivasa Rao , Bandi Vamsi Krishna
IPC分类号: C07D403/12 , C07D239/42
CPC分类号: C07D403/12 , C07D239/42
摘要: The present invention provides a commercially viable process for preparing pazopanib and its pharmaceutically acceptable acid addition salts thereof in high yields using novel intermediate. The present invention also provides a process for the purification of pazopanib hydrochloride.
摘要翻译: 本发明提供了使用新型中间体以高产率制备比唑帕尼及其药学上可接受的酸加成盐的商业上可行的方法。 本发明还提供了盐酸帕唑帕尼的纯化方法。
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公开(公告)号:US09096556B2
公开(公告)日:2015-08-04
申请号:US14122158
申请日:2012-05-21
申请人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Bandi Vamsi Krishna
发明人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Bandi Vamsi Krishna
IPC分类号: A61K31/427 , C07D417/12 , C07D277/28 , A61K45/06 , A61K47/32
CPC分类号: C07D277/28 , A61K31/427 , A61K45/06 , A61K47/32
摘要: The present invention relates to amorphous ritonavir co-precipitated on copovidone, process for its preparation and pharmaceutical compositions comprising it.
摘要翻译: 本发明涉及在共聚维酮上共沉淀的无定形利托那韦,其制备方法和包含它的药物组合物。
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公开(公告)号:US08703788B2
公开(公告)日:2014-04-22
申请号:US13989602
申请日:2011-11-11
申请人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Thungathurthy Srinivasa Rao , Bandi Vamsi Krishna
发明人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Thungathurthy Srinivasa Rao , Bandi Vamsi Krishna
IPC分类号: A01N43/54 , A61K31/505
CPC分类号: C07D401/14 , A61K31/506
摘要: The present invention provides a novel crystalline form of nilotinib hydrochloride, process for its preparation and pharmaceutical compositions comprising it.
摘要翻译: 本发明提供了盐酸尼洛替尼的新型结晶形式,其制备方法和包含其的药物组合物。
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公开(公告)号:US20140066468A1
公开(公告)日:2014-03-06
申请号:US14003535
申请日:2012-03-05
申请人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Kesireddy Subash Chander Reddy , Bandi Vamsi Krishna
发明人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Dasari Muralidhara Reddy , Kesireddy Subash Chander Reddy , Bandi Vamsi Krishna
IPC分类号: A61K31/513 , A61K31/427
CPC分类号: A61K31/513 , A61K31/427 , C07D239/10 , C07D417/12 , A61K2300/00
摘要: The present invention relates to a novel amorphous Form of lopinavir and ritonavir mixture in the ratio of 3.8:1.2 to 4.2:0.8, process for its preparation and pharmaceutical compositions comprising it.
摘要翻译: 本发明涉及以3.8:1.2至4.2:0.8的比例的洛匹那韦和利托那韦混合物的新型无定形形式,其制备方法和包含它的药物组合物。
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公开(公告)号:US08552036B2
公开(公告)日:2013-10-08
申请号:US13121443
申请日:2009-01-12
申请人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Rapolu Raji Reddy , Dasari Muralidhara Reddy , Kesireddy Subash Chander Reddy
发明人: Bandi Parthasaradhi Reddy , Kura Rathnakar Reddy , Rapolu Raji Reddy , Dasari Muralidhara Reddy , Kesireddy Subash Chander Reddy
IPC分类号: A61K31/4402 , C07D213/56
CPC分类号: C07D213/42
摘要: The present invention provides a novel crystalline form of atazanavir sulfate, process for its preparation and to pharmaceutical composition containing it. In accordance with the present invention atazanavir sulfate was dissolved in methanol, to the solution was added ethyl acetate, the solid obtained was collected by filtration and dried to give atazanavir sulfate crystalline form H1.
摘要翻译: 本发明提供了硫酸阿扎那韦的新型结晶形式,其制备方法和含有它的药物组合物。 根据本发明,将阿扎那韦硫酸盐溶于甲醇中,向该溶液中加入乙酸乙酯,过滤收集得到的固体,干燥得到硫酸阿扎那韦结晶形式H1。
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