公开(公告)号：US07368072B2

公开(公告)日：2008-05-06

申请号：US10315656

申请日：2002-12-10

申请人： Barry Van Gemert ,  Anil Kumar ,  Frank P. Mallak ,  Robert W. Walters

发明人： Barry Van Gemert ,  Anil Kumar ,  Frank P. Mallak ,  Robert W. Walters

IPC分类号： B29D11/00 ,  G02B3/00 ,  G02B1/00

CPC分类号： B29D11/00048 ,  B29D11/00317 ,  B29D11/00653

摘要： Described are contact lenses having photochromic materials within the central or pupillary area of the lens and methods for manufacturing such lenses. In one method, a photochromic amount of at least one photochromic material is added to the pupillary region of a casting mold containing a polymerizable monomer that can be at least partially cured before and/or after the addition. Another method involves providing an amount of polymerizable photochromic monomer for the pupillary region and an amount of polymerizable non-photochromic monomer for the remainder of the contact lens in a casting mold. The photochromic and non-photochromic monomers can differ by their degree of polymerization, viscosity and/or density.

摘要翻译： 描述了在透镜的中心或瞳孔区域内具有光致变色材料的隐形眼镜及其制造方法。 在一种方法中，将光致变色量的至少一种光致变色材料添加到含有可聚合单体的铸模的瞳孔区域中，该可聚合单体可以在添加之前和/或之后至少部分固化。 另一种方法包括提供一定量的用于瞳孔区域的可聚合光致变色单体和一定量的用于在模具中的隐形眼镜的其余部分的可聚合的非光致变色单体。 光致变色和非光致变色单体可以通过其聚合度，粘度和/或密度而不同。

公开(公告)号：US07094368B2

公开(公告)日：2006-08-22

申请号：US10732008

申请日：2003-12-10

申请人： Beon-Kyu Kim ,  Anil Kumar ,  Barry Van Gemert

发明人： Beon-Kyu Kim ,  Anil Kumar ,  Barry Van Gemert

IPC分类号： G02B5/23 ,  C08K5/1545 ,  G02C7/10

CPC分类号： C07D491/04

摘要： Described are compositions of at least one material represented by a pyrano[3,2-c]quinoline structure, a pyrano[3,2-c]quinolinone structure or mixtures thereof. The pyrano[3,2-c]quinoline structure is characterized by having a nitrogen atom at the 6-position ring atom and an oxy-substituent at the 5-position ring atom. The pyrano[3,2-c]quinolinone structure is characterized by having a substituted nitrogen atom at the 6-position ring atom and an oxo-substituent at the 5-position ring atom, the nitrogen atom substituents being hydrogen, aliphatic substituents, cycloaliphatic substituents, aromatic substituents, heteroaromatic substituents or a combination thereof. Both of the pyrano[3,2-c]quinoline and pyrano[3,2-c]quinolinone structures are characterized by having two substituents at the 2-position ring atom. Also described are photochromic articles that contain or that have coatings or films containing at least one of the novel compositions or combinations thereof with other photochromic materials.

摘要翻译： 描述了由吡喃并[3,2-c]喹啉结构，吡喃并[3,2-c]喹啉酮结构或其混合物表示的至少一种材料的组合物。 吡喃并[3,2-c]喹啉结构的特征在于在6-位环原子上具有氮原子和在5位环原子上具有氧取代基。 吡喃并[3,2-c]喹啉酮结构的特征在于在6位环原子上具有取代的氮原子，在5位环原子上具有氧代取代基，氮原子取代基为氢，脂族取代基，脂环族 取代基，芳族取代基，杂芳族取代基或其组合。 吡喃并[3,2-c]喹啉和吡喃并[3,2-c]喹啉酮结构的特征在于在2-位环原子上具有两个取代基。 还描述了含有或具有包含至少一种新组合物或其组合与其它光致变色材料的涂层或膜的光致变色制品。

公开(公告)号：US07320826B2

公开(公告)日：2008-01-22

申请号：US10393174

申请日：2003-03-20

申请人： Anil Kumar ,  Barry Van Gemert ,  Forrest R. Blackburn ,  Clara E. Nelson

发明人： Anil Kumar ,  Barry Van Gemert ,  Forrest R. Blackburn ,  Clara E. Nelson

IPC分类号： B32B17/10 ,  B32B27/20 ,  B32B27/36 ,  B32B33/00 ,  G02C7/10

CPC分类号： C09K9/02 ,  C07D311/94 ,  Y10S428/913 ,  Y10T428/31504 ,  Y10T428/31551 ,  Y10T428/31678 ,  Y10T428/31786 ,  Y10T428/31855 ,  Y10T428/31935 ,  Y10T428/31989 ,  Y10T428/31993

摘要： Described are photochromic articles that include a substrate, a temperature dependent reducing amount of at least one organic photochromic material (b) that changes from more absorbing to less absorbing of radiation in its activating spectral absorbance as the temperature increases from 10° C. to 35° C. and at least one other photochromic material (c) that is different from photochromic material (b). In the article, photochromic material (b) is interposed between photochromic material (c) and a source of activating radiation. The photochromic article demonstrates a more consistent photochromic response, for example, an optical density response loss of 50 percent or less over a temperature range of from 10° C. to 35° C. as measured in the Photochromic Temperature Dependence Test. Methods for producing the aforedescribed articles are also disclosed.

摘要翻译： 描述的是光致变色制品，其包括底物，至少一种有机光致变色材料（b）的温度依赖性降低量，其随着温度从10℃增加到35而在其激活光谱吸光度中从更吸收到更少吸收辐射 和与光致变色材料（b）不同的至少一种其它光致变色材料（c）。 在该制品中，光致变色材料（b）介于光致变色材料（c）和活化辐射源之间。 光致变色制品在光致变色温度依赖性测试中测得的光致变色响应表现出更一致的光致变色响应，例如在10℃至35℃的温度范围内的光密度响应损失为50％或更低。 还公开了制备上述制品的方法。

公开(公告)号：US5650098A

公开(公告)日：1997-07-22

申请号：US542999

申请日：1995-10-13

申请人： Anil Kumar ,  David B. Knowles ,  Barry Van Gemert

发明人： Anil Kumar ,  David B. Knowles ,  Barry Van Gemert

IPC分类号： C07D311/92 ,  C07D311/96 ,  C07D407/04 ,  C09K9/02 ,  G02B5/23 ,  C08K5/15

CPC分类号： C07D311/92 ,  C07D311/96 ,  C07D407/04 ,  C09K9/02 ,  G02B5/23

摘要： Described are novel reversible photochromic 2H-naphtho[1,2-b]pyran compounds, examples of which are compounds having certain substituents at the 5 and 6-positions of the naphtho portion of the naphthopyran and at the 2-position of the pyran ring, e.g., 2,2-bis(4-methoxy phenyl)-5-methoxycarbonyl-6-morpholino-2H-naphtho[1,2-b]pyran. Certain substituents may also be present at the number 7, 8, 9 or 10 carbon atoms of the naphtho portion of the naphthopyran. Also described are organic host materials that contain or that are coated with such compounds. Articles such as ophthalmic lenses or other plastic transparencies that incorporate the novel naphthopyran compounds or combinations thereof with complementary photochromic compounds, e.g., spiro(indoline) type compounds, are also described.

摘要翻译： 描述了新颖的可逆光致变色的2H-萘并[1,2-b]吡喃化合物，其实例是在萘并吡喃的萘酚部分的5位和6位具有某些取代基的化合物和吡喃环的2位 ，例如2,2-双（4-甲氧基苯基）-5-甲氧基羰基-6-吗啉代-2H-萘并[1,2-b]吡喃。 某些取代基也可以存在于萘并吡喃的萘酚部分的数目7,8,9或10个碳原子上。 还描述了含有或涂覆有这些化合物的有机主体材料。 还描述了将诸如螺旋（二氢吲哚）型化合物的引入新的萘并吡喃化合物或其组合与互补的光致变色化合物的眼用透镜或其它塑料透明胶片制成的物品。

公开(公告)号：US5658500A

公开(公告)日：1997-08-19

申请号：US490188

申请日：1995-06-14

申请人： Anil Kumar ,  David B. Knowles ,  Barry Van Gemert

发明人： Anil Kumar ,  David B. Knowles ,  Barry Van Gemert

IPC分类号： C07D311/94 ,  C07D405/04 ,  G02B5/23 ,  C08K5/15 ,  C07D311/78 ,  C07D405/02

CPC分类号： C07D405/04 ,  C07D311/94 ,  G02B5/23

摘要： Described are novel reversible photochromic 2H-naphtho[1,2-b]pyran compounds, examples of which are compounds having certain substituents at the number 5 carbon atom of the naphtho-portion of the naphthopyran and at the 2-position of the pyran ring. Certain substituents may also be present at the number 6, 7, 8, 9 or 10 carbon atoms of the naphtho portion of the naphthopyran. Also described are organic host materials that contain or that are coated with such compounds. Articles such as ophthalmic lenses or other plastic transparencies that incorporate the novel naphthopyran compounds or combinations thereof with complementary photochromic compounds, e.g., spiro(indoline) type compounds, are also described.

摘要翻译： 描述了新的可逆光致变色的2H-萘并[1,2-b]吡喃化合物，其实例是在萘并吡喃的萘酚部分的5个碳原子上具有某些取代基的化合物和在吡喃环的2位上 。 某些取代基也可以存在于萘并吡喃的萘酚部分的6,7,8,9或10个碳原子上。 还描述了含有或涂覆有这些化合物的有机主体材料。 还描述了将诸如螺旋（二氢吲哚）型化合物的引入新的萘并吡喃化合物或其组合与互补的光致变色化合物的眼用透镜或其它塑料透明胶片制成的物品。

公开(公告)号：US5466398A

公开(公告)日：1995-11-14

申请号：US80246

申请日：1993-06-21

申请人： Barry Van Gemert ,  Anil Kumar

发明人： Barry Van Gemert ,  Anil Kumar

IPC分类号： G02C7/10 ,  C07D311/92 ,  C07D311/96 ,  C07D405/04 ,  C07D407/04 ,  C07D409/04 ,  C08K5/10 ,  C08K5/1545 ,  C08L25/00 ,  C08L33/04 ,  C08L67/00 ,  C08L67/02 ,  C08L75/00 ,  C08L75/04 ,  C08L101/00 ,  C09K9/02 ,  C09K11/06 ,  G02B1/04 ,  G02B5/23 ,  G02B27/00

CPC分类号： G02B5/23 ,  C07D311/92

摘要： Described are novel reversible photochromic 3H-naphtho[2,1-b]pyran compounds, of the following graphic formula: ##STR1## wherein R.sub.1 is hydrogen or alkyl, R.sub.2 is hydrogen or preferably a carboalkoxy group and R.sub.3 is hydrogen or preferably an alkyl group, provided that either R.sub.1 or R.sub.2 is hydrogen, and B and B' are the aryl groups phenyl or naphthyl, a heterocyclic aromatic group or together form a spiro adamantylene group. Also described are organic host materials that contain or that are coated with such compounds. Articles such as ophthalmic lenses or other plastic transparencies that incorporate the novel naphthopyran compounds or combinations thereof with complementary photochromic compounds, e.g., spiro(oxazine) type compounds, are also described.

摘要翻译： 描述了新颖的可逆光致变色的3H-萘并[2,1-b]吡喃化合物，其具有下列结构式：其中R 1是氢或烷基，R 2是氢或优选烷氧基，R 3是氢或优选烷基 基团，其中R 1或R 2为氢，B和B'为芳基苯基或萘基，杂环芳基或一起形成螺金刚烷基。 还描述了含有或涂覆有这些化合物的有机主体材料。 还描述了将诸如螺旋（恶嗪）型化合物引入新颖的萘并吡喃化合物或其组合与互补的光致变色化合物，例如螺（恶嗪）类化合物的眼用透镜或其它塑料透明胶片的物品。

公开(公告)号：US07560056B2

公开(公告)日：2009-07-14

申请号：US12027522

申请日：2008-02-07

申请人： Barry Van Gemert ,  Anil Kumar ,  Frank P. Mallak ,  Robert W. Walters

发明人： Barry Van Gemert ,  Anil Kumar ,  Frank P. Mallak ,  Robert W. Walters

IPC分类号： G02C7/10 ,  B29D11/00

CPC分类号： B29D11/00048 ,  B29D11/00317 ,  B29D11/00653

摘要： Described are contact lenses having photochromic materials within the central or pupillary area of the lens and methods for manufacturing such lenses. In one method, a photochromic amount of at least one photochromic material is added to the pupillary region of a casting mold containing a polymerizable monomer that can be at least partially cured before and/or after the addition. Another method involves providing an amount of polymerizable photochromic monomer for the pupillary region and an amount of polymerizable non-photochromic monomer for the remainder of the contact lens in a casting mold. The photochromic and non-photochromic monomers can differ by their degree of polymerization, viscosity and/or density.

摘要翻译： 描述了在透镜的中心或瞳孔区域内具有光致变色材料的隐形眼镜及其制造方法。 在一种方法中，将光致变色量的至少一种光致变色材料添加到含有可聚合单体的铸模的瞳孔区域中，该可聚合单体可以在添加之前和/或之后至少部分固化。 另一种方法包括提供一定量的用于瞳孔区域的可聚合光致变色单体和一定量的用于在模具中的隐形眼镜的其余部分的可聚合的非光致变色单体。 光致变色和非光致变色单体可以通过其聚合度，粘度和/或密度而不同。

公开(公告)号：US20080125512A1

公开(公告)日：2008-05-29

申请号：US12027522

申请日：2008-02-07

申请人： Barry Van Gemert ,  Anil Kumar ,  Frank P. Mallak ,  Robert W. Walters

发明人： Barry Van Gemert ,  Anil Kumar ,  Frank P. Mallak ,  Robert W. Walters

IPC分类号： G02C7/04 ,  B29D11/02

CPC分类号： B29D11/00048 ,  B29D11/00317 ,  B29D11/00653

摘要： Described are contact lenses having photochromic materials within the central or pupillary area of the lens and methods for manufacturing such lenses. In one method, a photochromic amount of at least one photochromic material is added to the pupillary region of a casting mold containing a polymerizable monomer that can be at least partially cured before and/or after the addition. Another method involves providing an amount of polymerizable photochromic monomer for the pupillary region and an amount of polymerizable non-photochromic monomer for the remainder of the contact lens in a casting mold. The photochromic and non-photochromic monomers can differ by their degree of polymerization, viscosity and/or density.

摘要翻译： 描述了在透镜的中心或瞳孔区域内具有光致变色材料的隐形眼镜及其制造方法。 在一种方法中，将光致变色量的至少一种光致变色材料添加到含有可聚合单体的铸模的瞳孔区域中，该可聚合单体可以在添加之前和/或之后至少部分固化。 另一种方法包括提供一定量的用于瞳孔区域的可聚合光致变色单体和一定量的用于在模具中的隐形眼镜的其余部分的可聚合的非光致变色单体。 光致变色和非光致变色单体可以通过其聚合度，粘度和/或密度而不同。

公开(公告)号：US06348604B1

公开(公告)日：2002-02-19

申请号：US09656509

申请日：2000-09-06

申请人： Clara M. Nelson ,  Anu Chopra ,  David B. Knowles ,  Barry Van Gemert ,  Anil Kumar

发明人： Clara M. Nelson ,  Anu Chopra ,  David B. Knowles ,  Barry Van Gemert ,  Anil Kumar

IPC分类号： G02B523

CPC分类号： C07D311/92 ,  C07D493/04 ,  G02B5/23

摘要： Described are novel photochromic 2H-naphtho[1,2-b]pyran compounds essentially characterized by having two adjacent moderate to strong electron donor substituents at the 8 and 9 positions or a fused heterocyclic group formed by the substituents coming together, weak to moderate electron donors at the 2 position and a rating of at least 80 in the Relative &Dgr;OD at Saturation Test. The compounds also have certain substituents at the 5 position and optionally at the 6 position of the naphtho portion of the compound. These compounds may be represented by the following graphic formula: Also described are polymeric organic host materials that contain or that are coated with such compounds. Optically clear articles such as ophthalmic lenses or adjacent plastic transparencies that incorporate the novel naphthopyran compounds or combinations thereof with complementary photochromic compounds, e.g., certain other naphthopyrans, benzopyrans, and spiro(indoline)type compounds, are also described.

摘要翻译： 描述了新颖的光致变色2H-萘并[1,2-b]吡喃化合物，其基本上特征在于在8和9位具有两个相邻的中等至强电子给体取代基或由取代基组成的稠合杂环基团，弱至中等电子 捐助者在2位置，并且在饱和度测试的相对DELTAOD中评级至少为80。 化合物在化合物的萘酚部分的5位和任选地位置上也具有某些取代基。 这些化合物可以由以下图解表示：还描述了含有这些化合物或被这些化合物包被的聚合物有机主体材料。 还描述了光学透明的物品，例如将眼用透镜或相邻的塑料透明胶片结合到新的萘并吡喃化合物或其组合与互补光致变色化合物，例如某些其它萘并吡喃，苯并吡喃和螺（二氢吲哚）型化合物。

公开(公告)号：US06296785B1

公开(公告)日：2001-10-02

申请号：US09656510

申请日：2000-09-06

申请人： Clara M. Nelson ,  Anu Chopra ,  Olga G. Petrovskaia ,  David B. Knowles ,  Barry Van Gemert ,  Anil Kumar

发明人： Clara M. Nelson ,  Anu Chopra ,  Olga G. Petrovskaia ,  David B. Knowles ,  Barry Van Gemert ,  Anil Kumar

IPC分类号： C07D31178

CPC分类号： C07D311/94 ,  C07D311/96 ,  G02B5/23

摘要： Described are novel photochromic indeno-fused naphthopyran compounds, examples of which include naphthopyran compounds having a substituted or unsubstituted indeno group, the 2,1 positions of which are fused to the naphtho portion of the naphthopyran as shown below. Also present on the naphthopyran are moderate to strong electron donor substituents at the number 6- and 7-positions and optionally at the 8-position of the pyran ring or a cyclic group fused to the h side of the naphtho portion and weak to moderate electron donor substiuents at the 3-position of the pyran ring. Certain substituents may also be present at the number 5, 8, 9, 10, 11, 12, or 13 carbon atoms of the compounds. These compounds have a rating of at least 80 in the Relative &Dgr;OD at Saturation Test and may be represented by the following graphic formula: Also described are polymeric organic host materials that contain or that are coated with such compounds. Optically clear articles such as ophthalmic lenses or other plastic transparencies that incorporate the novel naphthopyran compounds or combinations thereof with complementary photochromic compounds, e.g., certain other naphthopyrans, benzopyrans, and spiro(indoline)type compounds, are also described.

摘要翻译： 描述了新的光致变色茚并稠合萘并吡喃化合物，其实例包括具有取代或未取代的茚并基团的萘并吡喃化合物，其2,1个位置与萘并吡喃的萘酚部分稠合，如下所示。 还存在于萘并吡喃上的是中子至强电子给体取代基，位于吡喃环的6-位和7-位，任选在8-位或稠合于萘酚部分的h侧的环状基团，弱至中等电子 在吡喃环3位的供体位。 某些取代基也可以存在于化合物的5,8,9,10,11,12或13个碳原子上。 这些化合物在饱和度测试中的相对DELTAOD中的等级至少为80，并且可以由以下图形表示：还描述了含有或涂覆有这些化合物的聚合物有机主体材料。 还描述了光学透明的物品，例如将眼用透镜或其它塑料透明胶片掺入新的萘并吡喃化合物或其组合与互补的光致变色化合物，例如某些其它萘并吡喃，苯并吡喃和螺（二氢吲哚）型化合物。