公开(公告)号：US10920228B2

公开(公告)日：2021-02-16

申请号：US16262769

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu

IPC: C12N15/11 ,  C12N15/115 ,  C12N15/10

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as biocide molecules.

公开(公告)号：US20210395920A1

公开(公告)日：2021-12-23

申请号：US17460513

申请日：2021-08-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu ,  Caitlin Bruns

IPC: C40B40/06 ,  C12Q1/6811 ,  C12Q1/6837

Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.

公开(公告)号：US11970785B2

公开(公告)日：2024-04-30

申请号：US17460513

申请日：2021-08-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu ,  Caitlin Bruns

IPC: C07H21/04 ,  C12Q1/6811 ,  C12Q1/6837 ,  C40B40/06

CPC classification number: C40B40/06 ,  C12Q1/6811 ,  C12Q1/6837 ,  C12Q1/6811 ,  C12Q2525/205 ,  C12Q2525/301 ,  C12Q2537/143 ,  C12Q2563/159 ,  C12Q2565/101 ,  C12Q2565/501 ,  C12Q1/6837 ,  C12Q2525/205 ,  C12Q2525/301 ,  C12Q2537/143 ,  C12Q2563/159 ,  C12Q2565/101

Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.

公开(公告)号：US11427825B2

公开(公告)日：2022-08-30

申请号：US16488239

申请日：2018-02-28

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Truong Nguyen ,  Rafal Drabek ,  Alexander S. Chiu ,  Deepak Thirunavukarasu ,  Vinoth Sankarapani

IPC: C12N15/115 ,  G01N33/53 ,  G01N33/94

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as drug compounds, such as levamisole and cocaine.

公开(公告)号：US20190242030A1

公开(公告)日：2019-08-08

申请号：US16262825

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu ,  Caitlin Bruns

IPC: C40B40/06

CPC classification number: C40B40/06

Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.

公开(公告)号：US11111603B2

公开(公告)日：2021-09-07

申请号：US16262825

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu ,  Caitlin Bruns

IPC: C07H21/04 ,  C40B40/06 ,  C12Q1/6811 ,  C12Q1/6837

Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.

公开(公告)号：US20190382766A1

公开(公告)日：2019-12-19

申请号：US16488239

申请日：2018-02-28

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Truong Nguyen ,  Rafal Drabek ,  Alexander S. Chiu ,  Deepak Thirunavukarasu ,  Vinoth Sankarapani

IPC: C12N15/115 ,  G01N33/53

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as drug compounds, such as levamisole and cocaine.

公开(公告)号：US20190233822A1

公开(公告)日：2019-08-01

申请号：US16262769

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu

IPC: C12N15/115 ,  C12N15/10

CPC classification number: C12N15/115 ,  C12N15/1048 ,  C12N2310/16

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as biocide molecules.