公开(公告)号：US10273215B2

公开(公告)日：2019-04-30

申请号：US15738470

申请日：2016-06-21

Applicant: Bayer CropScience Aktiengesellschaft ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Sergii Pazenok ,  Jean-Pierre Vors ,  Frédéric R. Leroux ,  Etienne Schmitt

IPC: C07D231/16 ,  C07C251/08 ,  C07C251/12 ,  C07C251/30 ,  C07C251/26

Abstract: The present invention relates to a novel process for preparing 3,5-bis substituted pyrazoles containing haloalkoxy- and haloalkylthio groups.

公开(公告)号：US10256109B2

公开(公告)日：2019-04-09

申请号：US15497393

申请日：2017-04-26

Applicant: American Air Liquide, Inc.

Inventor： Vijay Surla ,  Rahul Gupta ,  Venkateswara R. Pallem

IPC: H01L21/311 ,  C07C255/10 ,  C07C251/08 ,  C07C251/26 ,  H01L21/02 ,  H01L21/027 ,  H01L27/108 ,  H01L27/115

Abstract: A method for etching silicon-containing films is disclosed. The method includes the steps of introducing a vapor of a nitrogen containing etching compound into a reaction chamber containing a silicon-containing film on a substrate, wherein the nitrogen containing etching compound is an organofluorine compound containing at least one C≡N or C═N functional group; introducing an inert gas into the reaction chamber; and activating a plasma to produce an activated nitrogen containing etching compound capable of etching the silicon-containing film from the substrate.

公开(公告)号：US09659788B2

公开(公告)日：2017-05-23

申请号：US14841271

申请日：2015-08-31

Applicant: American Air Liquide, Inc.

Inventor： Vijay Surla ,  Rahul Gupta ,  Venkateswara R. Pallem

IPC: H01L21/311 ,  C07C255/10 ,  C07C251/08 ,  C07C251/26

CPC classification number: H01L21/31116 ,  C07C251/08 ,  C07C251/26 ,  C07C255/10 ,  H01L21/31144

Abstract: A method for etching silicon-containing films is disclosed. The method includes the steps of introducing a vapor of a nitrogen containing etching compound into a reaction chamber containing a silicon-containing film on a substrate, wherein the nitrogen containing etching compound is an organofluorine compound containing at least one C≡N or C═N functional group; introducing an inert gas into the reaction chamber; and activating a plasma to produce an activated nitrogen containing etching compound capable of etching the silicon-containing film from the substrate.

公开(公告)号：US5990161A

公开(公告)日：1999-11-23

申请号：US222870

申请日：1998-12-30

Applicant: Yoshie Kirio ,  Takako Maeda ,  Norio Sasaki ,  Norishige Toshima ,  Nobumitsu Sawai ,  Bruce Milligan ,  Joseph Perez ,  Jean-Pierre Vors ,  Daniel B. Gant

Inventor： Yoshie Kirio ,  Takako Maeda ,  Norio Sasaki ,  Norishige Toshima ,  Nobumitsu Sawai ,  Bruce Milligan ,  Joseph Perez ,  Jean-Pierre Vors ,  Daniel B. Gant

IPC: C07D239/34 ,  A01N37/36 ,  A01N37/52 ,  C07C20060101 ,  C07C251/10 ,  C07C259/06 ,  C07C259/08 ,  C07C259/10 ,  C07C317/28 ,  C07C327/58 ,  C07C327/60 ,  C07C333/12 ,  C07C335/40 ,  A01N33/24 ,  C07C251/26

CPC classification number: A01N37/52 ,  C07C259/06 ,  C07C259/08 ,  C07C259/10 ,  C07C327/58 ,  C07C327/60

Abstract: Hydroximic acid derivatives, useful as pesticides, have the formula ##STR1## in which G is G.sub.3 or G.sub.4 having the formula: ##STR2## in which R.sub.5 is lower alkyl; R.sub.6 and R.sub.7 are, independently, hydrogen or lower alkyl; W is O, S, SO or SO.sub.2 ; X.sub.1, X.sub.2 and X.sub.3 are, independently, hydrogen or a variety of substituents; and R.sub.1, R.sub.2 and R.sub.3 are, independently, hydrogen or a variety of substituents.

Abstract translation: 可用作农药的羟基亚氨酸衍生物具有下列通式：其中G为具有下式的G 3或G 4：其中R 5为低级烷基; R6和R7独立地是氢或低级烷基; W是O，S，SO或SO2; X1，X2和X3独立地是氢或各种取代基; 且R 1，R 2和R 3独立地为氢或各种取代基。

公开(公告)号：US20180186749A1

公开(公告)日：2018-07-05

申请号：US15738470

申请日：2016-06-21

Applicant: Bayer CropScience Aktiengesellschaft ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Inventor： Sergii PAZENOK ,  Jean-Pierre VORS ,  Frédéric R. LEROUX ,  Etienne SCHMITT

IPC: C07D231/16 ,  C07C251/08 ,  C07C251/12 ,  C07C251/26 ,  C07C251/30

CPC classification number: C07D231/16 ,  C07C251/08 ,  C07C251/12 ,  C07C251/26 ,  C07C251/30

Abstract: The present invention relates to a novel process for preparing 3,5-bis substituted pyrazoles containing haloalkoxy- and haloalkylthio groups.

公开(公告)号：US09750717B2

公开(公告)日：2017-09-05

申请号：US15019581

申请日：2016-02-09

Applicant: Ludwig-Maximilians-Universitaet Muenchen ,  Maastricht University ,  Academisch Ziekenhuis Maastricht

Inventor： Esther Lutgens ,  Christian Weber ,  Gerry Nicolaes

IPC: A61K31/381 ,  C07D333/22 ,  C07C251/24 ,  C07C251/26 ,  C07D307/52 ,  A61K31/137 ,  A61K31/341

CPC classification number: A61K31/381 ,  A61K31/137 ,  A61K31/341 ,  C07C251/24 ,  C07C251/26 ,  C07D307/52 ,  C07D333/22

Abstract: The present invention relates to compounds acting as selective inhibitors of CD40-TRAF6 interaction, their use as medicaments and their use in the treatment of (chronic) inflammatory diseases. The present invention also relates to pharmaceutical compositions comprising these compounds.

公开(公告)号：US09408829B2

公开(公告)日：2016-08-09

申请号：US14417708

申请日：2013-08-27

Applicant: Ludwig-Maximilians-Universitaet Muenchen ,  Maastricht University ,  Academisch Ziekenhuis Maastricht

Inventor： Esther Lutgens ,  Christian Weber ,  Gerry Nicolaes

IPC: A01N43/06 ,  A01N43/08 ,  A61K31/135 ,  A61K31/381 ,  C07D333/22 ,  C07C251/24 ,  C07C251/26 ,  C07D307/52 ,  A61K31/137 ,  A61K31/341

CPC classification number: A61K31/381 ,  A61K31/137 ,  A61K31/341 ,  C07C251/24 ,  C07C251/26 ,  C07D307/52 ,  C07D333/22

Abstract: The present invention relates to compounds acting as selective inhibitors of CD40-TRAF6 interaction, their use as medicaments and their use in the treatment of (chronic) inflammatory diseases. The present invention also relates to pharmaceutical compositions comprising these compounds.

Abstract translation: 本发明涉及作为CD40-TRAF6相互作用的选择性抑制剂的化合物，它们作为药物的用途及其在治疗（慢性）炎性疾病中的用途。 本发明还涉及包含这些化合物的药物组合物。

公开(公告)号：US6121451A

公开(公告)日：2000-09-19

申请号：US230245

申请日：1997-10-02

Applicant: Kevin E. Henegar ,  John C. Sih

Inventor： Kevin E. Henegar ,  John C. Sih

IPC: C07D491/147 ,  A61K31/435 ,  A61K31/436 ,  A61K31/4738 ,  A61P35/00 ,  C07C251/26 ,  C07C271/44 ,  C07D213/30 ,  C07D213/61 ,  C07D213/64 ,  C07D213/643 ,  C07D213/79 ,  C07D405/04 ,  C07D471/04 ,  C07D471/14 ,  C07D491/04 ,  C07D491/052 ,  C07D491/14 ,  C07D491/22

CPC classification number: C07D213/64 ,  C07D213/61 ,  C07D213/643 ,  C07D213/79 ,  C07D405/04 ,  C07D471/04 ,  C07D471/14 ,  C07D491/04 ,  C07D491/14

Abstract: This invention relates to intermediates and processes for the synthesis of camtothecin derivatives, such as irinotecan. Related procedures and compounds are disclosed, such as a method of making mappicine.

Abstract translation: PCT No.PCT / US96 / 04163 Sec。 371 1997年10月2日第 102（e）日期1997年10月2日PCT提交1996年4月1日PCT公布。 出版物WO96 / 31513 PCT 日期1996年10月10日本发明涉及合成喜树碱衍生物如伊立替康的中间体和方法。 公开了相关方法和化合物，例如制备地图的方法。

公开(公告)号：US5189060A

公开(公告)日：1993-02-23

申请号：US621157

申请日：1990-11-30

Applicant: David B. Kanne ,  Karl J. Fisher ,  Michael D. Broadhurst

Inventor： David B. Kanne ,  Karl J. Fisher ,  Michael D. Broadhurst

IPC: A01N37/52 ,  A01N43/08 ,  A01N43/30 ,  A01N43/32 ,  A01N43/40 ,  A01N53/00 ,  C07C67/00 ,  C07C241/00 ,  C07C249/02 ,  C07C251/12 ,  C07C251/26 ,  C07C251/30 ,  C07C255/61 ,  C07C257/06 ,  C07C257/08 ,  C07C317/22 ,  C07C317/36 ,  C07C317/42 ,  C07C323/20 ,  C07C323/36 ,  C07C323/43 ,  C07D213/64 ,  C07D213/68 ,  C07D307/42 ,  C07D317/66 ,  A61K37/52 ,  A61K31/21 ,  C07D213/643

CPC classification number: C07D317/66 ,  A01N37/52 ,  A01N43/08 ,  A01N43/40 ,  A01N53/00 ,  C07C255/61

Abstract: Novel insecticides have the formula ##STR1## in which R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy or C.sub.1 -C.sub.4 haloalkylthio;R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy or C.sub.1 -C.sub.4 haloalkylthio;R.sub.3 is hydrogen, halogen or C.sub.1 -C.sub.4 haloalkyl; orR.sub.1 and R.sub.2 taken together are C.sub.1 -C.sub.4 alkylenedioxy or halo-C.sub.1 -C.sub.3 alkylenedioxy; provided that R.sub.1, R.sub.2 and R.sub.3 are not all hydrogen;R.sub.4 is methyl, ethyl, n-propyl, C.sub.3 -C.sub.7 branched alkyl, C.sub.1 -C.sub.6 haloalkyl, C.sub.2 -C.sub.4 alkenyl; or cyclopropyl, optionally substituted by up to 4 methyl groups or up to 2 halogens;R.sub.5 is: ##STR2## R.sub.6 is phenyl, benzyl, C.sub.3 -C.sub.4 alkenyl, or C.sub.3 alkynyl; R.sub.7, R.sub.8, R.sub.10 and R.sub.11 are each halogen; andR.sub.9 is methyl, methoxymethyl, methylthio, methylthiomethyl, hydroxymethyl, cyanomethyl, benzyl, C.sub.3 -C.sub.4 alkenyl, C.sub.3 alkynyl or propargylamino.