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公开(公告)号：US20150342939A1
公开(公告)日：2015-12-03
申请号：US14729630
申请日：2015-06-03
Applicant: Baylor Research Institute
Inventor： Raphael Schiffmann , Fanny Mochel , Lawrence Sweetman , Sabrina Fomi
IPC: A61K31/445
CPC classification number: A61K31/445 , A61B10/0051 , A61B10/0058 , A61B10/007 , A61B2010/0061 , G01N2030/8831
Abstract: The present invention describes a method for determination of urinary globotriaosylceramide (Gb3) levels in non-Fabry disease cardiac patients. Determination of Gb3 levels provides a screening method for determining cardiac risk and may offer an alternative therapeutic option for cardiac disease management or cardiac disease risk mitigation by lowering Gb3 levels by the use of pharmacological chaperones or other agents.
Abstract translation: 本发明描述了非法布里病心脏病患者尿球蛋白神经酰胺（Gb3）水平的测定方法。 Gb3水平的测定提供了一种用于确定心脏病风险的筛选方法，并且可以通过使用药理学伴侣或其他药物降低Gb3水平来提供心脏疾病管理或心脏疾病风险缓解的替代治疗选择。
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Patent Agency Ranking
公开(公告)号：US10111848B2
公开(公告)日：2018-10-30
申请号：US15257363
申请日：2016-09-06
Inventor： Fanny Mochel , Raphael Schiffmann
IPC: A61K31/225 , A01N37/06 , A01N37/02 , A61K31/23 , A61K45/06 , A23L33/12 , A61B6/03 , A61B6/00 , A61K9/00 , A61K9/48 , G01N33/64
Abstract: Provided are methods for treating GLUT1 and related brain energy deficiencies comprising administering odd-carbon fatty acid sources, e.g., C5 or C7 fatty acid sources, and related compositions.
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公开(公告)号：US20160374980A1
公开(公告)日：2016-12-29
申请号：US15257363
申请日：2016-09-06
Inventor： Fanny Mochel , Raphael Schiffmann
CPC classification number: A61K31/225 , A23L33/12 , A23V2002/00 , A61B6/037 , A61B6/501 , A61K9/0053 , A61K9/48 , A61K31/23 , A61K45/06 , G01N33/64 , A61K2300/00
Abstract: Provided are methods for treating GLUT1 and related brain energy deficiencies comprising administering odd-carbon fatty acid sources, e.g., C5 or C7 fatty acid sources, and related compositions.
Abstract translation: 提供了治疗GLUT1和相关脑能量缺乏的方法，其包括施用奇 - 碳脂肪酸来源，例如C5或C7脂肪酸来源以及相关组合物。
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公开(公告)号：US20140221482A1
公开(公告)日：2014-08-07
申请号：US14106078
申请日：2013-12-13
Inventor： Fanny Mochel , Raphael Schiffmann
CPC classification number: A61K31/225 , A23L33/12 , A23V2002/00 , A61B6/037 , A61B6/501 , A61K9/0053 , A61K9/48 , A61K31/23 , A61K45/06 , G01N33/64 , A61K2300/00
Abstract: Provided are methods for treating GLUT1 and related brain energy deficiencies comprising administering odd-carbon fatty acid sources, e.g., C5 or C7 fatty acid sources, and related compositions.
Abstract translation: 提供了治疗GLUT1和相关脑能量缺乏的方法，其包括施用奇 - 碳脂肪酸来源，例如C5或C7脂肪酸来源以及相关组合物。
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公开(公告)号：US09750732B2
公开(公告)日：2017-09-05
申请号：US14729630
申请日：2015-06-03
Applicant: Baylor Research Institute
Inventor： Raphael Schiffmann , Fanny Mochel , Lawrence Sweetman , Sabrina Forni
IPC: A61K31/445 , A61B10/00 , G01N30/88
CPC classification number: A61K31/445 , A61B10/0051 , A61B10/0058 , A61B10/007 , A61B2010/0061 , G01N2030/8831
Abstract: The present invention describes a method for determination of urinary globotriaosylceramide (Gb3) levels in non-Fabry disease cardiac patients. Determination of Gb3 levels provides a screening method for determining cardiac risk and may offer an alternative therapeutic option for cardiac disease management or cardiac disease risk mitigation by lowering Gb3 levels by the use of pharmacological chaperones or other agents.
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公开(公告)号：US09468229B2
公开(公告)日：2016-10-18
申请号：US14106078
申请日：2013-12-13
Inventor： Fanny Mochel , Raphael Schiffmann
CPC classification number: A61K31/225 , A23L33/12 , A23V2002/00 , A61B6/037 , A61B6/501 , A61K9/0053 , A61K9/48 , A61K31/23 , A61K45/06 , G01N33/64 , A61K2300/00
Abstract: Provided are methods for treating GLUT1 and related brain energy deficiencies comprising administering odd-carbon fatty acid sources, e.g., C5 or C7 fatty acid sources, and related compositions.
Abstract translation: 提供了治疗GLUT1和相关脑能量缺乏的方法，其包括施用奇 - 碳脂肪酸来源，例如C5或C7脂肪酸来源以及相关组合物。
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