公开(公告)号：US08985281B2

公开(公告)日：2015-03-24

申请号：US13480793

申请日：2012-05-25

申请人： Beat De Coi ,  Steven Freedman ,  Jan Giger ,  Tobias Leutenegger

发明人： Beat De Coi ,  Steven Freedman ,  Jan Giger ,  Tobias Leutenegger

IPC分类号： B66B1/34

CPC分类号： B66B1/3492

摘要： An elevator installation with an elevator cab in an elevator shaft and a measurement tape for determining the position of the elevator cab within the elevator shaft, which measurement tape is arranged vertically in the elevator shaft and has a code along the measurement tape, and at least one marking element which is attached in the elevator shaft and has a reference marking, and a sensor apparatus which is attached to the elevator cab and includes an illumination source and a sensor, which form a detection field for detecting the measurement tape and with an evaluation apparatus. The reference marking is arranged such that it can be captured by the detection field and the sensor apparatus is also provided for detecting the reference marking and the evaluation apparatus aligns the position determined by the measurement tape with the reference marking.

摘要翻译： 具有电梯轿厢的升降机装置和用于确定电梯井内的电梯轿厢的位置的测量带，该测量带垂直设置在电梯井中并且具有沿测量带的代码，至少 一个标记元件，其安装在电梯井中并具有参考标记;以及传感器设备，其附接到电梯轿厢并包括照明源和传感器，其形成用于检测测量带的检测区域和评估 仪器。 参考标记被布置成使得其可以被检测区捕获，并且还提供传感器装置用于检测参考标记，并且评估装置将由测量带确定的位置与参考标记对齐。

公开(公告)号：US20130284544A1

公开(公告)日：2013-10-31

申请号：US13480793

申请日：2012-05-25

申请人： Beat DE COI ,  Steven Freedman ,  Jan Giger ,  Tobias Leutenegger

发明人： Beat DE COI ,  Steven Freedman ,  Jan Giger ,  Tobias Leutenegger

IPC分类号： G01D5/347 ,  B66B3/02

CPC分类号： B66B1/3492

摘要： An elevator installation with an elevator cab in an elevator shaft and a measurement tape for determining the position of the elevator cab within the elevator shaft, which measurement tape is arranged vertically in the elevator shaft and has a code along the measurement tape, and at least one marking element which is attached in the elevator shaft and has a reference marking, and a sensor apparatus which is attached to the elevator cab and comprises an illumination source and a sensor, which form a detection field for detecting the measurement tape and with an evaluation apparatus. The reference marking is arranged such that it can be captured by the detection field and the sensor apparatus is also provided for detecting the reference marking and the evaluation apparatus aligns the position determined by the measurement tape with the reference marking.

摘要翻译： 具有电梯轿厢的升降机装置和用于确定电梯井内的电梯轿厢的位置的测量带，该测量带垂直设置在电梯井中并且具有沿测量带的代码，至少 一个标记元件，其附接在电梯井中并具有参考标记;以及传感器设备，其附接到电梯轿厢并包括照明源和传感器，其形成用于检测测量带的检测区域和评估 仪器。 参考标记被布置成使得其可以被检测区捕获，并且还提供传感器装置用于检测参考标记，并且评估装置将由测量带确定的位置与参考标记对齐。

公开(公告)号：US08857572B2

公开(公告)日：2014-10-14

申请号：US13530168

申请日：2012-06-22

申请人： Tobias Leutenegger ,  Steven Freedman

发明人： Tobias Leutenegger ,  Steven Freedman

IPC分类号： B66B3/00 ,  B66B1/34 ,  B66B3/02

CPC分类号： B66B1/3492 ,  B66B3/023

摘要： An elevator device for transporting persons and/or objects within an elevator shaft of a three-dimensional formation including at least two levels, in particular a building or the like. The elevator device includes an elevator car, in which the persons and/or objects to be transported can be accommodated, a running framework for mounting and guiding the elevator car, a position determining device for determining the position of the elevator car within the elevator shaft and/or with respect to the running framework. The position determining device includes marking units for marking the position of the elevator car relative to the running framework and the elevator shaft, a detection unit for detecting and/or reading out the marking units and also an evaluation unit for evaluating the measured values of the detection unit. The marking units are formed as carriers of a barcode, in particular a 2-D code, and the detection unit is formed as an image sensor, in particular as a camera.

摘要翻译： 一种电梯装置，用于运输包括至少两个层次的三维地层的电梯井道内的人员和/或物体，特别是建筑物等。 电梯装置包括可以容纳人和物体的电梯轿厢，用于安装和引导电梯轿厢的行驶框架，用于确定电梯轿厢内电梯轿厢位置的位置确定装置 和/或关于运行框架。 位置确定装置包括用于标记电梯轿厢相对于运行框架和电梯井的位置的标记单元，用于检测和/或读出标记单元的检测单元，以及用于评估电梯轿厢的测量值的评估单元 检测单元 标记单元形成为条形码的载体，特别是2-D代码，并且检测单元形成为图像传感器，特别是作为相机。

公开(公告)号：US20130001023A1

公开(公告)日：2013-01-03

申请号：US13530168

申请日：2012-06-22

申请人： Tobias Leutenegger ,  Steven Freedman

发明人： Tobias Leutenegger ,  Steven Freedman

IPC分类号： B66B3/02

CPC分类号： B66B1/3492 ,  B66B3/023

摘要： An elevator device for transporting persons and/or objects within an elevator shaft of a three-dimensional formation including at least two levels, in particular a building or the like. The elevator device includes an elevator car, in which the persons and/or objects to be transported can be accommodated, a running framework for mounting and guiding the elevator car, a position determining device for determining the position of the elevator car within the elevator shaft and/or with respect to the running framework. The position determining device includes a marking unit for marking the position, a detection unit for detecting and/or reading out the marking unit and also an evaluation unit for evaluating the measured values of the detection unit. The marking unit is formed as a carrier of a barcode, in particular a 2-D code, and the detection unit is formed as an image sensor, in particular as a camera.

摘要翻译： 一种电梯装置，用于运输包括至少两个层次的三维地层的电梯井道内的人员和/或物体，特别是建筑物等。 电梯装置包括可以容纳人和物体的电梯轿厢，用于安装和引导电梯轿厢的行驶框架，用于确定电梯轿厢内电梯轿厢位置的位置确定装置 和/或关于运行框架。 位置确定装置包括用于标记位置的标记单元，用于检测和/或读出标记单元的检测单元，以及用于评估检测单元的测量值的评估单元。 标记单元形成为条形码的载体，特别是2-D代码，并且检测单元形成为图像传感器，特别是作为照相机。

公开(公告)号：US08988213B2

公开(公告)日：2015-03-24

申请号：US13284005

申请日：2011-10-28

申请人： Tobias Leutenegger ,  Steven Freedman

发明人： Tobias Leutenegger ,  Steven Freedman

IPC分类号： G08B1/00 ,  E06B9/88 ,  G08B23/00 ,  G08B13/18 ,  H01J40/14 ,  E06B3/00 ,  E06B9/68 ,  E05F15/00

CPC分类号： E06B9/88 ,  E05F2015/436 ,  E05Y2900/00 ,  E05Y2900/106 ,  E06B2009/6827 ,  E06B2009/6836

摘要： A safety device for safeguarding a movable, guided movement element against undesired collisions with an object situated on a movement path of the movement element, said device comprising at least two sensors for detecting the object and the movement element and for outputting signals depending on the detection, and also having an evaluation unit for evaluating signals of the sensors and for generating a switch-off signal on the basis of the evaluation. For improved recognition of a risk of collision, the evaluation unit is designed to acquire from the at least two sensors a currently detected state vector from a set of state vectors which unambiguously comprise all possible combinations of the signals of the sensors, and to generate the switch-off signal in the case of predetermined state vectors.

摘要翻译： 一种用于保护可移动的被引导的运动元件以防止与位于运动元件的运动路径上的物体的不希望的碰撞的安全装置，所述装置包括用于检测物体和运动元件的至少两个传感器，并且用于根据检测来输出信号 并且还具有用于评估传感器的信号并根据评估产生关断信号的评估单元。 为了改善对碰撞风险的识别，评估单元被设计为从一组状态向量中从至少两个传感器获取当前检测到的状态向量，其明确地包括传感器的信号的所有可能组合，并且生成 在预定状态向量的情况下关断信号。

公开(公告)号：US20060160867A1

公开(公告)日：2006-07-20

申请号：US11262645

申请日：2005-10-31

申请人： Steven Freedman

发明人： Steven Freedman

IPC分类号： A61K31/426 ,  A61K31/198

CPC分类号： A61K31/198 ,  A61K31/426

摘要： This invention features methods for treating diseases associated with mutations in the CFTR gene by administering PPAR agonists, specifically PPARγ, PPARα, and PPARδ agonists, PPAR inducers, and/or antioxidants. Also disclosed are screening methods for identifying therapeutically useful candidate compounds.

摘要翻译： 本发明的特征在于通过施用PPAR激动剂，特别是PPARγ，PPARα和PPARδ激动剂，PPAR诱导剂和/或抗氧化剂来治疗与CFTR基因突变相关的疾病的方法。 还公开了用于鉴定治疗有用的候选化合物的筛选方法。

公开(公告)号：US06552081B1

公开(公告)日：2003-04-22

申请号：US09706404

申请日：2000-11-03

申请人： Steven Freedman ,  Juan G. Alvarez

发明人： Steven Freedman ,  Juan G. Alvarez

IPC分类号： A61K3120

CPC分类号： A61K31/202 ,  A23L33/12

摘要： A method of treating disorders in which DHA levels are affected is described. The method includes administering to a subject suffering from the disorder a therapeutically affective amount of DHA. This method is particularly useful in treating subjects suffering from a disorder characterized by a defect in the CF gene, e.g., cystic fibrosis, or a chronic inflammatory disorder, e.g., ulcerative colitis, Crohn's disease, chronic pancreatitis, asthma, rheumatoid arthritis or chronic gastritis. A method of ameliorating affects of cystic fibrosis in a newborn and a method of increasing surfactant levels in a fetus are also described.

摘要翻译： 描述了一种治疗其中DHA水平受到影响的疾病的方法。 该方法包括给患有该病症的受试者施用治疗上有意义的量的DHA。 该方法特别适用于治疗以CF基因缺陷为特征的疾病，例如囊性纤维化或慢性炎症性疾病，例如溃疡性结肠炎，克罗恩病，慢性胰腺炎，哮喘，类风湿性关节炎或慢性胃炎 。 还描述了改善新生儿囊性纤维化的影响的方法和增加胎儿中表面活性剂水平的方法。

公开(公告)号：US06180671B2

公开(公告)日：2001-01-30

申请号：US09248471

申请日：1999-02-11

申请人： Steven Freedman ,  Juan G. Alvarez

发明人： Steven Freedman ,  Juan G. Alvarez

IPC分类号： A61K3120

CPC分类号： A61K31/202 ,  A23L33/12

摘要： A method of treating disorders in which DHA levels are affected is described. The method includes administering to a subject suffering from the disorder a therapeutically affective amount of DHA. This method is particularly useful in treating subjects suffering from a disorder characterized by a defect in the CF, gene, e.g. cystic fibrosis, or a chronic inflammatory disorder, e.g., ulcerative colitis, Crohn's disease, chronic pancreatitis, asthma, rheumatoid arthritis or chronic gastritis. A method of ameliorating affects of cystic fibrosis in a newborn and a method of increasing surfactant levels in a fetus are also described.

摘要翻译： 描述了一种治疗其中DHA水平受到影响的疾病的方法。 该方法包括给患有该病症的受试者施用治疗上有意义的量的DHA。 该方法特别可用于治疗患有以CF，基因例如缺陷为特征的疾病的受试者。 囊性纤维化或慢性炎症性疾病，例如溃疡性结肠炎，克罗恩病，慢性胰腺炎，哮喘，类风湿性关节炎或慢性胃炎。 还描述了改善新生儿囊性纤维化的影响的方法和增加胎儿中表面活性剂水平的方法。

公开(公告)号：US20100239559A1

公开(公告)日：2010-09-23

申请号：US12587579

申请日：2009-10-09

申请人： Steven Freedman ,  Deborah A. DaSilva

发明人： Steven Freedman ,  Deborah A. DaSilva

IPC分类号： A61K38/46 ,  A61K38/47 ,  A61K38/48 ,  C12N9/20 ,  C12N9/26 ,  C12N9/48 ,  A61P1/14

CPC分类号： C12Y301/01003 ,  A23L33/135 ,  A23L33/17 ,  A23L33/195 ,  A23L33/40

摘要： The present invention is directed to novel food products, e.g., nutritional food products and infant formula, which contain one ore more enzymes selected from lipase, protease, and amylase that have been formulated/stabilized to have sustained stability in an aqueous medium. Such formulations are intended to provide a greater degree of compliance based on their ability to be incorporated into aqueous media while avoiding unstable breakdown of the enzyme and large overdosing due to expected breakdown when exposed to an aqueous environment, including saliva. Further described in the invention are additives packaged with instructions for combination with an aqueous medium, and instructions for the administration of the resulting mixture to a subject. In certain embodiments, enzyme insufficient patients, e.g., infants and elderly persons, would find particular benefit from the food products described herein.

摘要翻译： 本发明涉及新的食品，例如营养食品和婴儿配方食品，其含有一种或多种选自脂肪酶，蛋白酶和淀粉酶的酶，其已被配制/稳定以在水性介质中具有持续的稳定性。 这样的制剂旨在基于它们掺入水性介质中的能力而提供更大程度的依从性，同时避免酶的不稳定分解，并且当暴露于包括唾液在内的水性环境时，由于预期的分解导致的大量过量。 在本发明中进一步描述的是包含与水性介质组合的说明书的添加剂以及将所得混合物施用于受试者的说明书。 在某些实施方案中，酶不足的患者，例如婴儿和老年人，将从本文所述的食品中获益。

公开(公告)号：US20050099958A1

公开(公告)日：2005-05-12

申请号：US10702365

申请日：2003-11-06

申请人： Steven Freedman

发明人： Steven Freedman

IPC分类号： H04L20060101 ,  H04L12/26 ,  H04Q3/00

CPC分类号： H04Q3/0087 ,  H04Q3/0025

摘要： Methods and systems for automated analysis of signaling link utilization are disclosed. A method for automatically analyzing signaling link utilization includes displaying signaling link utilization data to a user via a computer display device. User input regarding a portion of the link utilization data that the user desires to analyze is received. Signaling message data corresponding to the selected link utilization data is automatically extracted from a database. The signaling message data may be used to determine the cause of signaling link utilization problems.

摘要翻译： 公开了用于信令链路利用的自动分析的方法和系统。 用于自动分析信令链路利用的方法包括经由计算机显示设备向用户显示信令链路利用数据。 接收关于用户期望分析的链路利用率数据的一部分的用户输入。 从数据库中自动提取与所选择的链接利用数据相对应的信令消息数据。 信令消息数据可用于确定信令链路利用问题的原因。