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公开(公告)号：US12053620B2
公开(公告)日：2024-08-06
申请号：US16741239
申请日：2020-01-13
发明人： Michael Vincent Quinn , Trivikrama Bhanoji Pala , Philip Song , David Aubrey Plumptre , Malcolm Stanley Boyd , Peter Quinn
CPC分类号： A61M5/315 , A61M5/24 , A61M5/31515 , A61M5/14248 , A61M2005/14252 , A61M5/2033 , A61M2005/206 , A61M2005/31518 , A61M5/31533 , A61M5/3234 , A61M2207/00
摘要： A drug delivery system for injecting a medicament includes a container including a closure and a stopper configured to move within the container from a pre-use position to a post-use position. The system includes a drive assembly configured to move the stopper between first and second positions, and a spacer assembly engaged with the stopper configured to be engaged by the drive assembly. The spacer assembly includes a first spacer portion received within the stopper, a second spacer portion spaced from the first spacer portion, an inner plunger, and a spacer shuttle received by the inner plunger. The inner plunger, the spacer shuttle, and the second portion are configured to move relative to the stopper, where movement of the second spacer portion is restricted by the spacer shuttle, movement of the spacer shuttle is restricted by the inner plunger, and movement of the inner plunger is restricted by the stopper.
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公开(公告)号：US20240148980A1
公开(公告)日：2024-05-09
申请号：US18417604
申请日：2024-01-19
CPC分类号： A61M5/3158 , A61M5/14248 , A61M5/31536 , A61M5/3232 , A61M5/3293 , A61M5/50 , A61M2005/2073
摘要： A needle actuator assembly for a drug delivery system includes a housing, a needle having retracted and extended positions, a needle actuator body received within the housing and configured to move from a pre-use position where the needle is in the retracted position to a use position where the needle is in the extended position and to a post-use position where the needle is in the retracted position, with the needle actuator having a button contact surface, and an actuator button received by the housing.
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公开(公告)号：US20200345943A1
公开(公告)日：2020-11-05
申请号：US16929875
申请日：2020-07-15
摘要： A needle actuator assembly for a drug delivery system includes a housing, a needle having retracted and extended positions, a needle actuator body received within the housing and configured to move from a pre-use position where the needle is in the retracted position to a use position where the needle is in the extended position and to a post-use position where the needle is in the retracted position, with the needle actuator having a button contact surface, and an actuator button received by the housing.
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公开(公告)号：US10960134B2
公开(公告)日：2021-03-30
申请号：US16160184
申请日：2018-10-15
发明人： Jamie Anthony Salter , Oliver Charles Gazeley , David Aubrey Plumptre , James Alexander Senior , Gareth James Lewis , Malcolm Stanley Boyd , Javier Eduardo Nadal
摘要： A drug delivery system for injecting a medicament is provided. The system includes a container configured to receive a medicament; a drive assembly which, upon actuation, is configured to expel the medicament from the container; a needle for injecting the medicament to a patient; a fluid path assembly comprising a tube in fluid communication with the container and the needle for conducting fluid from the container to the needle; and a tube crimping arrangement configured to engage the tube to block fluid flow through the tube. The drive assembly causes the tube crimping arrangement to engage the tube after a dose of the medicament has been delivered to the patient through the needle.
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公开(公告)号：US10751476B2
公开(公告)日：2020-08-25
申请号：US15616235
申请日：2017-06-07
摘要： A needle actuator assembly for a drug delivery system includes a housing, a needle having retracted and extended positions, a needle actuator body received within the housing and configured to move from a pre-use position where the needle is in the retracted position to a use position where the needle is in the extended position and to a post-use position where the needle is in the retracted position, with the needle actuator having a button contact surface, and an actuator button received by the housing.
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公开(公告)号：US20220257867A1
公开(公告)日：2022-08-18
申请号：US17739816
申请日：2022-05-09
发明人： Richard James Vincent Avery , Malcolm Stanley Boyd , Oliver Charles Gazeley , Gareth James Lewis , David Aubrey Plumptre , James Alexander Senior
摘要： A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.
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公开(公告)号：US10792432B2
公开(公告)日：2020-10-06
申请号：US15616250
申请日：2017-06-07
发明人： Oliver Charles Gazeley , David Aubrey Plumptre , Malcolm Stanley Boyd , Gareth James Lewis , James Alexander Senior
摘要： A drug delivery system for injecting a medicament includes a housing, a container configured to receive a medicament including a stopper configured to move within the container and a closure, a needle in fluid communication with the container, a spacer configured to be engaged with the stopper, a first plunger, a first spring configured to bias the first plunger in an axial direction, second plunger disposed about the first plunger, a second spring configured to bias the second plunger in an axial direction. The first plunger is configured to move the spacer and the container relative to the housing via the first spring to establish fluid communication between the container and the patient needle, and the second plunger is configured to move the spacer and the stopper relative to the container via the second spring.
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公开(公告)号：US20190111207A1
公开(公告)日：2019-04-18
申请号：US16160184
申请日：2018-10-15
发明人： Jamie Anthony Salter , Oliver Charles Gazeley , David Aubrey Plumptre , James Alexander Senior , Gareth James Lewis , Malcolm Stanley Boyd , Javier Eduardo Nadal
摘要： A drug delivery system for injecting a medicament is provided. The system includes a container configured to receive a medicament; a drive assembly which, upon actuation, is configured to expel the medicament from the container; a needle for injecting the medicament to a patient; a fluid path assembly comprising a tube in fluid communication with the container and the needle for conducting fluid from the container to the needle; and a tube crimping arrangement configured to engage the tube to block fluid flow through the tube. The drive assembly causes the tube crimping arrangement to engage the tube after a dose of the medicament has been delivered to the patient through the needle.
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公开(公告)号：US20240091452A1
公开(公告)日：2024-03-21
申请号：US18510201
申请日：2023-11-15
发明人： Oliver Charles Gazeley , David Aubrey Plumptre , Malcolm Stanley Boyd , Gareth James Lewis , James Alexander Senior
CPC分类号： A61M5/315 , A61M5/1454 , A61M5/2033 , A61M5/24 , A61M5/31511 , A61M2207/00
摘要： A drug delivery system for injecting a medicament includes a housing, a container configured to receive a medicament including a stopper configured to move within the container and a closure, a needle in fluid communication with the container, a spacer configured to be engaged with the stopper, a first plunger, a first spring configured to bias the first plunger in an axial direction, second plunger disposed about the first plunger, a second spring configured to bias the second plunger in an axial direction. The first plunger is configured to move the spacer and the container relative to the housing via the first spring to establish fluid communication between the container and the patient needle, and the second plunger is configured to move the spacer and the stopper relative to the container via the second spring.
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公开(公告)号：US11357918B2
公开(公告)日：2022-06-14
申请号：US16160231
申请日：2018-10-15
发明人： Richard James Vincent Avery , Malcolm Stanley Boyd , Oliver Charles Gazeley , Gareth James Lewis , David Aubrey Plumptre , James Alexander Senior
摘要： A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.
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