公开(公告)号：US20180340131A1

公开(公告)日：2018-11-29

申请号：US16048926

申请日：2018-07-30

Applicant: Becton Dickinson France

Inventor： Virginie Santucci-Aribert ,  Emanuela Rossito

IPC: C10M107/50 ,  B65D39/00 ,  B05D3/06 ,  B05D5/08 ,  A61M5/31

Abstract: The invention relates to a lubricant coating for a medical container comprising a cross-linked lubricant composition comprising a mixture of non-reactive silicone with reactive silicone, characterized in that the reactive silicone comprises a mixture of vinyl-based silicone and acrylate-based silicone. The invention further relates to a lubricant composition usable as an intermediate product in the fabrication of a lubricant coating. The invention further relates to a medical container comprising a barrel and a stopper in gliding engagement within the barrel, comprising such a lubricant coating. The invention also relates to a process of manufacturing a medical container comprising a barrel and a stopper in gliding engagement within the barrel including depositing a lubricant composition on the inner surface of the barrel and/or on the stopper, and irradiating the coated barrel and/or stopper so as to cross-link the lubricant composition to form a lubricant coating.

公开(公告)号：US11779706B2

公开(公告)日：2023-10-10

申请号：US17464397

申请日：2021-09-01

Applicant: Becton Dickinson France

Inventor： Cédric Foucher ,  Virginie Santucci-Aribert

IPC: A61M5/31 ,  C10M107/50 ,  B05D3/14 ,  C10M155/02 ,  C10N40/00 ,  C10N50/00 ,  C10N60/04 ,  C10N70/00

CPC classification number: A61M5/3129 ,  B05D3/147 ,  B05D3/148 ,  C10M107/50 ,  C10M155/02 ,  A61M2005/3131 ,  A61M2205/0222 ,  A61M2205/0238 ,  C10M2229/0415 ,  C10N2040/50 ,  C10N2050/023 ,  C10N2060/04 ,  C10N2070/00 ,  C10M2229/0415 ,  C10N2060/04

Abstract: The invention relates to a lubricant coating (5) for a medical injection device (1), comprising successively: —a bottom layer (50) in contact with the medical device surface (21) of the container to be lubricated, comprising a mixture of cross-linked and non-cross-linked poly-(dimethylsiloxane), —an intermediate layer (51) consisting essentially of oxidized poly-(dimethylsiloxane) and having a thickness comprised between 10 and 30 nm and, —a top layer (52) consisting essentially of non-cross-linked poly-(dimethylsiloxane) and having a thickness of at most 2 nm. The invention also relates to a medical injection device comprising such a lubricant coating, and a manufacturing process for said coating.

公开(公告)号：US20210393881A1

公开(公告)日：2021-12-23

申请号：US17464397

申请日：2021-09-01

Applicant: Becton Dickinson France

Inventor： Cédric Foucher ,  Virginie Santucci-Aribert

IPC: A61M5/31 ,  C10M107/50 ,  B05D3/14 ,  C10M155/02

Abstract: The invention relates to a lubricant coating (5) for a medical injection device (1), comprising successively: —a bottom layer (50) in contact with the medical device surface (21) of the container to be lubricated, comprising a mixture of cross-linked and non-cross-linked poly-(dimethylsiloxane), —an intermediate layer (51) consisting essentially of oxidized poly-(dimethylsiloxane) and having a thickness comprised between 10 and 30 nm and, —a top layer (52) consisting essentially of non-cross-linked poly-(dimethylsiloxane) and having a thickness of at most 2 nm. The invention also relates to a medical injection device comprising such a lubricant coating, and a manufacturing process for said coating.

公开(公告)号：US09993597B2

公开(公告)日：2018-06-12

申请号：US14404153

申请日：2013-05-29

Applicant: Becton Dickinson France

Inventor： Cédric Foucher ,  Virginie Santucci-Aribert

IPC: B01D19/04 ,  A61M25/00 ,  B05D3/00 ,  A61M5/315 ,  A61M5/31 ,  C10M107/50 ,  B05D3/14 ,  C10M155/02

CPC classification number: A61M5/3129 ,  A61M2005/3131 ,  A61M2205/0222 ,  A61M2205/0238 ,  B05D3/147 ,  B05D3/148 ,  C10M107/50 ,  C10M155/02 ,  C10M2229/0415 ,  C10N2240/66 ,  C10N2250/14 ,  C10N2260/04 ,  C10N2270/00

Abstract: The invention relates to a lubricant coating (5) for a medical injection device (1), comprising successively: —a bottom layer (50) in contact with the medical device surface (21) of the container to be lubricated, comprising a mixture of cross-linked and non-cross-linked poly-(dimethylsiloxane), —an intermediate layer (51) consisting essentially of oxidized poly-(dimethylsiloxane) and having a thickness comprised between 10 and 30 nm and, —a top layer (52) consisting essentially of non-cross-linked poly-(dimethylsiloxane) and having a thickness of at most 2 nm. The invention also relates to a medical injection device comprising such a lubricant coating, and a manufacturing process for said coating.

公开(公告)号：US20180304021A1

公开(公告)日：2018-10-25

申请号：US15978475

申请日：2018-05-14

Applicant: Becton Dickinson France

Inventor： Cédric Foucher ,  Virginie Santucci-Aribert

IPC: A61M5/31 ,  C10M155/02 ,  B05D3/14 ,  C10M107/50

CPC classification number: A61M5/3129 ,  A61M2005/3131 ,  A61M2205/0222 ,  A61M2205/0238 ,  B05D3/147 ,  B05D3/148 ,  C10M107/50 ,  C10M155/02 ,  C10M2229/0415 ,  C10N2240/66 ,  C10N2250/14 ,  C10N2260/04 ,  C10N2270/00

Abstract: The invention relates to a lubricant coating (5) for a medical injection device (1), comprising successively: —a bottom layer (50) in contact with the medical device surface (21) of the container to be lubricated, comprising a mixture of cross-linked and non-cross-linked poly-(dimethylsiloxane), —an intermediate layer (51) consisting essentially of oxidized poly-(dimethylsiloxane) and having a thickness comprised between 10 and 30 nm and, —a top layer (52) consisting essentially of non-cross-linked poly-(dimethylsiloxane) and having a thickness of at most 2 nm. The invention also relates to a medical injection device comprising such a lubricant coating, and a manufacturing process for said coating.

公开(公告)号：US20150322366A1

公开(公告)日：2015-11-12

申请号：US14399192

申请日：2013-05-07

Applicant: Becton Dickinson France

Inventor： Virginie Santucci-Aribert ,  Emanuela Rossito

IPC: C10M107/50 ,  B05D5/08 ,  B65D39/00 ,  B05D3/06

CPC classification number: C10M107/50 ,  A61L29/06 ,  A61L29/14 ,  A61L2400/10 ,  A61M5/3129 ,  A61M2005/3131 ,  B05D3/068 ,  B05D5/08 ,  B65D39/0005 ,  B65D2539/008 ,  C08G77/20 ,  C09D183/04 ,  C10M2229/0415 ,  C10M2229/0435 ,  C10N2220/022 ,  C10N2230/06 ,  C10N2230/10 ,  C10N2230/68 ,  C10N2240/66 ,  C10N2250/10 ,  C10N2250/121 ,  C08L83/00

Abstract: The invention relates to a lubricant coating for a medical container comprising a cross-linked lubricant composition comprising a mixture of non-reactive silicone with reactive silicone, characterized in that the reactive silicone comprises a mixture of vinyl-based silicone and acrylate-based silicone. The invention further relates to a lubricant composition usable as an intermediate product in the fabrication of a lubricant coating. The invention further relates to a medical container comprising a barrel and a stopper in gliding engagement within the barrel, comprising such a lubricant coating. The invention also relates to a process of manufacturing a medical container comprising a barrel and a stopper in gliding engagement within the barrel including depositing a lubricant composition on the inner surface of the barrel and/or on the stopper, and irradiating the coated barrel and/or stopper so as to cross-link the lubricant composition to form a lubricant coating.

Abstract translation: 本发明涉及一种用于医疗容器的润滑剂涂层，其包括交联润滑剂组合物，其包含非反应性硅氧烷与反应性硅氧烷的混合物，其特征在于反应性硅氧烷包括基于乙烯基的硅氧烷和基于丙烯酸酯的硅氧烷的混合物。 本发明还涉及可用作制造润滑剂涂层的中间产品的润滑剂组合物。 本发明还涉及一种医疗容器，其包括在筒体内滑动接合的筒体和塞子，包括这种润滑剂涂层。 本发明还涉及一种制造医疗容器的方法，该药物容器包括在枪管内滑动接合的枪管和止动器，包括在枪管的内表面上和/或在止动器上沉积润滑剂组合物，以及照射涂覆枪管和/ 或塞子，以便使润滑剂组合物交联以形成润滑剂涂层。

公开(公告)号：US11135370B2

公开(公告)日：2021-10-05

申请号：US15978475

申请日：2018-05-14

Applicant: Becton Dickinson France

Inventor： Cédric Foucher ,  Virginie Santucci-Aribert

IPC: A61M5/31 ,  C10M107/50 ,  B05D3/14 ,  C10M155/02 ,  C10N40/00 ,  C10N50/00 ,  C10N60/04 ,  C10N70/00

Abstract: The invention relates to a lubricant coating (5) for a medical injection device (1), comprising successively: —a bottom layer (50) in contact with the medical device surface (21) of the container to be lubricated, comprising a mixture of cross-linked and non-cross-linked poly-(dimethylsiloxane), —an intermediate layer (51) consisting essentially of oxidized poly-(dimethylsiloxane) and having a thickness comprised between 10 and 30 nm and, —a top layer (52) consisting essentially of non-cross-linked poly-(dimethylsiloxane) and having a thickness of at most 2 nm. The invention also relates to a medical injection device comprising such a lubricant coating, and a manufacturing process for said coating.

公开(公告)号：US10066182B2

公开(公告)日：2018-09-04

申请号：US14399192

申请日：2013-05-07

Applicant: Becton Dickinson France

Inventor： Virginie Santucci-Aribert ,  Emanuela Rossito

IPC: C10M107/50 ,  B05D5/08 ,  B65D39/00 ,  B05D3/06 ,  A61M5/31 ,  A61L29/06 ,  A61L29/14 ,  C09D183/04 ,  C08G77/20

CPC classification number: C10M107/50 ,  A61L29/06 ,  A61L29/14 ,  A61L2400/10 ,  A61M5/3129 ,  A61M2005/3131 ,  B05D3/068 ,  B05D5/08 ,  B65D39/0005 ,  B65D2539/008 ,  C08G77/20 ,  C09D183/04 ,  C10M2229/0415 ,  C10M2229/0435 ,  C10N2220/022 ,  C10N2230/06 ,  C10N2230/10 ,  C10N2230/68 ,  C10N2240/66 ,  C10N2250/10 ,  C10N2250/121 ,  C08L83/00

Abstract: The invention relates to a lubricant coating for a medical container comprising a cross-linked lubricant composition comprising a mixture of non-reactive silicone with reactive silicone, characterized in that the reactive silicone comprises a mixture of vinyl-based silicone and acrylate-based silicone. The invention further relates to a lubricant composition usable as an intermediate product in the fabrication of a lubricant coating. The invention further relates to a medical container comprising a barrel and a stopper in gliding engagement within the barrel, comprising such a lubricant coating. The invention also relates to a process of manufacturing a medical container comprising a barrel and a stopper in gliding engagement within the barrel including depositing a lubricant composition on the inner surface of the barrel and/or on the stopper, and irradiating the coated barrel and/or stopper so as to cross-link the lubricant composition to form a lubricant coating.

公开(公告)号：US20150165125A1

公开(公告)日：2015-06-18

申请号：US14404153

申请日：2013-05-29

Applicant: Becton Dickinson France

Inventor： Cédric Foucher ,  Virginie Santucci-Aribert

IPC: A61M5/31 ,  C10M155/02 ,  B05D3/14

CPC classification number: A61M5/3129 ,  A61M2005/3131 ,  A61M2205/0222 ,  A61M2205/0238 ,  B05D3/147 ,  B05D3/148 ,  C10M107/50 ,  C10M155/02 ,  C10M2229/0415 ,  C10N2240/66 ,  C10N2250/14 ,  C10N2260/04 ,  C10N2270/00

Abstract: The invention relates to a lubricant coating (5) for a medical injection device (1), comprising successively: —a bottom layer (50) in contact with the medical device surface (21) of the container to be lubricated, comprising a mixture of cross-linked and non-cross-linked poly-(dimethylsiloxane), —an intermediate layer (51) consisting essentially of oxidized poly-(dimethylsiloxane) and having a thickness comprised between 10 and 30 nm and, —a top layer (52) consisting essentially of non-cross-linked poly-(dimethylsiloxane) and having a thickness of at most 2 nm. The invention also relates to a medical injection device comprising such a lubricant coating, and a manufacturing process for said coating.

Abstract translation: 本发明涉及一种用于医疗注射装置（1）的润滑剂涂层（5），其包括： - 与要润滑的容器的医疗装置表面（21）接触的底层（50），包括： 交联和非交联的聚（二甲基硅氧烷）， - 基本上由氧化的聚（二甲基硅氧烷）组成并且具有10至30nm的厚度的中间层（51）和 - 顶层（52） 基本上由非交联聚（二甲基硅氧烷）组成，厚度至多为2nm。 本发明还涉及包括这种润滑剂涂层的医疗注射装置和用于所述涂层的制造方法。