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公开(公告)号：US11526028B2
公开(公告)日：2022-12-13
申请号：US16940509
申请日：2020-07-28
发明人： Fan-Dan Jan
摘要： The invention is to provide an ophthalmic lens comprising a lens body and an antimicrobial hydrophilic layer thereon and a manufacturing method thereof, wherein the antimicrobial hydrophilic layer comprises a polydopamine layer and a zwitterionic polymer non-covalently bonded on the polydopamine layer, and the zwitterionic polymer can be selected from one of the group consisting of phosphorylcholine polymer, sulfobetaine polymer, carboxybetaine polymer, mixed-charge polymer and a combination thereof.
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公开(公告)号：US10795180B2
公开(公告)日：2020-10-06
申请号：US15679741
申请日：2017-08-17
发明人： Fan-Dan Jan
摘要： The invention is to provide an ophthalmic lens comprising a lens body and an antimicrobial hydrophilic layer thereon and a manufacturing method thereof, wherein the antimicrobial hydrophilic layer comprises a polydopamine layer and a zwitterionic polymer non-covalently bonded on the polydopamine layer, and the zwitterionic polymer can be selected from one of the group consisting of phosphorylcholine polymer, sulfobetaine polymer, carboxybetaine polymer, mixed-charge polymer and a combination thereof.
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公开(公告)号：US10429671B2
公开(公告)日：2019-10-01
申请号：US15912582
申请日：2018-03-06
发明人： Fan-Dan Jan
IPC分类号： G02C7/04 , A61L27/34 , A61L27/54 , G02B1/14 , G02B1/04 , G02C7/02 , G02B1/18 , A61F2/16 , B29D11/00 , G02B1/12
摘要： The invention is to provide an ophthalmic lens and a manufacturing method thereof. The ophthalmic lens comprises a lens body and an antimicrobial hydrophilic layer thereon, wherein the antimicrobial hydrophilic layer comprises tannic acid and a zwittericionic polymer. The zwittericionic polymer can be selected from one of the group consisting of a phosphorylcholine polymer, a sulfobetaine polymer, a carboxybetaine polymer and a mixed-charge polymer or combinations thereof.
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公开(公告)号：US20180292677A1
公开(公告)日：2018-10-11
申请号：US15679741
申请日：2017-08-17
发明人： Fan-Dan Jan
摘要： The invention is to provide an ophthalmic lens comprising a lens body and an antimicrobial hydrophilic layer thereon and a manufacturing method thereof, wherein the antimicrobial hydrophilic layer comprises a polydopamine layer and a zwitterionic polymer non-covalently bonded on the polydopamine layer, and the zwitterionic polymer can be selected from one of the group consisting of phosphorylcholine polymer, sulfobetaine polymer, carboxybetaine polymer, mixed-charge polymer and a combination thereof.
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5.发明授权公开(公告)号：US09116284B2
公开(公告)日：2015-08-25
申请号：US13916609
申请日：2013-06-13
发明人： Fan-Dan Jan
IPC分类号： C08G77/20 , G02B1/04 , C08F230/08 , C08L83/08 , C08G77/26 , C08G77/388
CPC分类号： G02B1/043 , C08F230/08 , C08G77/20 , C08G77/26 , C08G77/388 , C08L83/08 , C08L101/14 , C08L83/04 , C08F226/10 , C08F220/20 , C08F220/54
摘要： A material is provided for contact lens including a first siloxane macromer represented by the following formula (I): wherein R1, R2 and R3 are independently C1-C12 hydroxyl group, C1-C12 alkyl groups or C1-C12 siloxane group; R4 is C1-C6 alkylene group or C1-C6 alkylene substituted with ether group; R5 is —H, —CH3, —CH(CH3)2, —CH(CH3)CH2(CH3), —CH2CH(CH3)2, —CH2C6H5, —CH2OH, —CH(OH)CH3, —CH2CONH2 or —CH2CH2CONH2: R6 is —NHCONH—, —NHCO—, —R8NHCONH— or —R8NHCO—, wherein R8 is —O—, —O(CH2)n— or —(CH2)n— and n is an integer of 1-10; R7 is hydrogen or methyl; and m is an integer of 10-100.
摘要翻译： 提供了用于隐形眼镜的材料，其包括由下式（I）表示的第一硅氧烷大分子单体：其中R1，R2和R3独立地为C1-C12羟基，C1-C12烷基或C1-C12硅氧烷基; R4是C1-C6亚烷基或被醚基取代的C1-C6亚烷基; R5是-H，-CH3，-CH（CH3）2，-CH（CH3）CH2（CH3），-CH2CH（CH3）2，-CH2C6H5，-CH2OH，-CH（OH）CH3，-CH2CONH2或-CH2CH2CONH2 ：R6是-NHCONH-，-NHCO-，-R8NHCONH-或-R8NHCO-，其中R8是-O-，-O（CH2）n-或 - （CH2）n-，n是1-10的整数; R7是氢或甲基; m为10〜100的整数。
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公开(公告)号：US09085697B2
公开(公告)日：2015-07-21
申请号：US13923382
申请日：2013-06-21
发明人： Fan-Dan Jan , Hsia-Hao Chang
IPC分类号： C09B29/12
CPC分类号： C09B29/12 , C09B29/10 , C09B29/34 , C09B69/106 , G02B1/043 , C08L33/26 , C08L33/10 , C08L101/14 , C08L83/04
摘要： A polymerizable yellow dye which is used to block or lower the intensity of blue light transmitted through ophthalmic lenses and is represented by the following formula (I): wherein R1 is hydrogen or —NHCOCH3; R2 is hydrogen or C1-C3 alkyl groups; R3 and R4 are independently hydrogen or —OCO—R5, wherein R5 is isopropenyl group or a substituted isopropenyl group represented as —R6—(R7O)n—COC(CH3)CH2, R6 is NH or R7 is C1-C5 alkylene groups and n is an integer of 1-40.
摘要翻译： 一种可聚合的黄色染料，其用于阻挡或降低透过眼镜片的蓝光的强度，并由下式（I）表示：其中R1为氢或-NHCOCH3; R2是氢或C1-C3烷基; R3和R4独立地是氢或-OCO-R5，其中R5是异丙烯基或由-R6-（R7O）n-COC（CH3）CH2表示的取代的异丙烯基，R6是NH或R7是C1-C5亚烷基， n为1-40的整数。
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公开(公告)号：US10782449B2
公开(公告)日：2020-09-22
申请号：US15679812
申请日：2017-08-17
发明人： Fan-Dan Jan
摘要： The invention is to provide an ophthalmic lens and manufacturing method thereof. The ophthalmic lens comprises a lens body, a polydopamine layer formed on a surface of the lens body and a first cellulose nanofiber (CNF) layer bonded to the polydopamine layer.
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公开(公告)号：US20180292575A1
公开(公告)日：2018-10-11
申请号：US15679787
申请日：2017-08-17
发明人： Fan-Dan Jan
摘要： The invention is to provide an ophthalmic lens comprising a lens body, a polydopamine layer formed on the surface of the lens body and an antimicrobial layer bonded to the polydopamine layer, and manufacturing method thereof, wherein the antimicrobial layer is formed from a copolymer of carboxyl-containing polymer and zwitterionic polymer and a crosslinking agent, and the zwitterionic polymer can be selected from one of the group consisting of phosphorylcholine polymer, sulfobetaine polymer, carboxybetaine polymer and mixed-charge polymer or a combination thereof.
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公开(公告)号：US09958578B2
公开(公告)日：2018-05-01
申请号：US15441252
申请日：2017-02-24
发明人： Fan-Dan Jan , Pei-Yi Liu
CPC分类号： G02B1/043 , B29D11/00038 , B29D11/00134 , B29K2083/00 , B29K2105/0002 , B29K2105/0005 , B29K2105/0032 , B29K2995/0092 , C08G77/20 , C08G77/26 , C08G77/38 , C08G77/388 , C08G77/46 , C08G77/54 , C08L83/08 , C08L83/12 , C08L83/04 , C08L83/00
摘要： The invention provides a material including a first siloxane macromer shown as formula (I): in which R1, R2 and R3 are C1-C4 alkyl groups, R4 is C1-C6 alkyl group, R5 is C1-C4 alkylene group, R6 is —OR7O— or —NH—, R7 and R8 are C1-C4 alkylene groups and m is an integer of 1-2, n is an integer of 4-80; a second siloxane macromer shown as formula (II): in which R9, R10 and R11 are C1-C4 alkyl groups, R12, R13 and R15 are C1-C3 alkylene group, R14 is a residue obtained by removing NCO group from an aliphatic or aromatic diisocyanate, and o is an integer of 4-80, p is an integer of 0-1; q is an integer of about 1-20; at least one hydrophilic monomer and an initiator.
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10.发明授权公开(公告)号：US09804297B2
公开(公告)日：2017-10-31
申请号：US14941668
申请日：2015-11-16
发明人： Fan-Dan Jan , Hsiu-Hao Chang
IPC分类号： C08L83/02 , G02C7/04 , G02B1/04 , B29D11/00 , C08F290/06 , C08G77/38 , B29K83/00 , B29K105/00
CPC分类号： G02B1/043 , B29D11/00038 , B29K2083/00 , B29K2105/0061 , B29K2995/0092 , C08F290/062 , C08G77/38 , C08L83/04
摘要： The invention provides a material for contact lenses, including a first siloxane macromer shown as formula (I): wherein R1, R2 and R3 are independently C1-C4 alkyl groups, R4 is C1-C6 alkyl group, R5 is C1-C3 alkylene group, R6 is —OR7O— or —NH—, R7 and R8 are independently C1-C2 alkylene groups and m is an integer of about 1-2, n is an integer of about 4-80; at least one hydrophilic monomer; a surfactant which is an urethane (meth)acrylate containing poloxamer and an initiator.
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