公开(公告)号：US11203018B2

公开(公告)日：2021-12-21

申请号：US16160816

申请日：2018-10-15

Applicant: Berkeley Lights, Inc.

Inventor： Troy A. Lionberger ,  Matthew E. Fowler ,  Phillip J. M. Elms ,  Kevin D. Loutherback ,  Randall D. Lowe, Jr. ,  Jian Gong ,  J. Tanner Nevill ,  Gang F. Wang ,  Gregory G. Lavieu ,  John A. Tenney ,  Aathavan Karunakaran ,  Anupam Singhal ,  I-Jong Lin

IPC: B01L3/00 ,  G01N21/64 ,  B03C5/02 ,  B03C5/00 ,  B01L9/00 ,  G06T7/00 ,  G01N21/05

Abstract: Methods, systems and kits are described herein for detecting the results of an assay. In particular, the methods, systems and devices of the present disclosure rely on a difference between the diffusion rates of a reporter molecule and an analyte of interest in order to quantify an amount of analyte in a microfluidic device. The analyte may be a secreted product of a biological micro-object.

公开(公告)号：US11789016B2

公开(公告)日：2023-10-17

申请号：US16849811

申请日：2020-04-15

Applicant: Berkeley Lights, Inc.

Inventor： Troy A. Lionberger ,  Phillip J. M. Elms ,  Anupam Singhal ,  Randall D. Lowe, Jr. ,  Volker L. S. Kurz ,  Paul M. Lebel

IPC: B01L3/00 ,  G01N33/543 ,  G01N33/68

CPC classification number: G01N33/54366 ,  B01L3/502761 ,  G01N33/6854 ,  B01L2200/0668 ,  B01L2300/0654 ,  B01L2300/0864 ,  B01L2300/165 ,  B01L2300/1822 ,  B01L2400/0424 ,  B01L2400/0457 ,  B01L2400/0472 ,  B01L2400/086

Abstract: Methods, systems and kits are described herein for detecting the results of an assay. In particular, the methods, systems and devices of the present disclosure rely on a difference between the diffusion rates of a reporter molecule and an analyte of interest in order to quantify an amount of analyte in a microfluidic device. The analyte may be a secreted product of a biological micro-object.