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1.发明授权Biosorbable wound treatment device, process for making, and method of using the same 有权生物可收缩伤口治疗装置，制造方法及其使用方法公开(公告)号：US09381269B2
公开(公告)日：2016-07-05
申请号：US13428370
申请日：2012-03-23
CPC分类号： A61L15/425 , A61L15/44 , A61L15/60 , A61L2300/11 , C08L5/04 , C08L5/08 , C08L3/04 , C08L67/04
摘要： A biosorbable oxygen-delivery wound treatment device that includes a biosorbable matrix for delivering oxygen. The biosorbable matrix includes a water swellable, cross-linked biosorbable polymer network. A plurality of gas-permeable, elastic, closed cells is defined by the cross-linked biosorbable polymer network. According to the invention, these closed cells may be produced from a reaction between a catalyst and a second reactant. Deliverable oxygen is contained within the elastic closed cells such that when the device is used to treat a wound, oxygen is delivered from the closed cells. A process for making a biosorbable oxygen-delivery wound treatment device that includes a biosorbable matrix for delivering oxygen as well as a method of using an oxygen-delivery wound treatment device is disclosed.
摘要翻译： 一种生物可吸收氧传递伤口治疗装置，其包括用于输送氧气的生物可吸收基质。 生物可吸收的基质包括水可溶胀的交联的可生物吸收的聚合物网络。 通过交联的生物可吸收聚合物网络限定多个透气的，弹性的闭孔。 根据本发明，这些闭孔可以由催化剂和第二反应物之间的反应产生。 可弹性的氧被包含在弹性封闭的细胞内，使得当该装置用于治疗伤口时，从封闭的细胞输送氧气。 本发明公开了一种生产可吸收的氧传递伤口治疗装置的方法，该装置包括用于输送氧的生物可吸收基质以及使用氧传递伤口治疗装置的方法。
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2.发明申请Biosorbable Wound Treatment Device, Process for Making, and Method of Using the Same 有权生物可触及伤口治疗装置，制造方法及其使用方法公开(公告)号：US20120265124A1
公开(公告)日：2012-10-18
申请号：US13428370
申请日：2012-03-23
IPC分类号： A61M37/00
CPC分类号： A61L15/425 , A61L15/44 , A61L15/60 , A61L2300/11 , C08L5/04 , C08L5/08 , C08L3/04 , C08L67/04
摘要： A biosorbable oxygen-delivery wound treatment device that includes a biosorbable matrix for delivering oxygen. The biosorbable matrix includes a water swellable, cross-linked biosorbable polymer network. A plurality of gas-permeable, elastic, closed cells is defined by the cross-linked biosorbable polymer network. According to the invention, these closed cells may be produced from a reaction between a catalyst and a second reactant. Deliverable oxygen is contained within the elastic closed cells such that when the device is used to treat a wound, oxygen is delivered from the closed cells. A process for making a biosorbable oxygen-delivery wound treatment device that includes a biosorbable matrix for delivering oxygen as well as a method of using an oxygen-delivery wound treatment device is disclosed.
摘要翻译： 一种生物可吸收氧传递伤口治疗装置，其包括用于输送氧气的生物可吸收基质。 生物可吸收的基质包括水可溶胀的交联的可生物吸收的聚合物网络。 通过交联的生物可吸收聚合物网络限定多个透气的，弹性的闭孔。 根据本发明，这些闭孔可以由催化剂和第二反应物之间的反应产生。 可弹性的氧被包含在弹性封闭的细胞内，使得当该装置用于治疗伤口时，从封闭的细胞输送氧气。 本发明公开了一种生产可吸收的氧传递伤口治疗装置的方法，该装置包括用于输送氧的生物可吸收基质以及使用氧传递伤口治疗装置的方法。
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公开(公告)号：US08652531B2
公开(公告)日：2014-02-18
申请号：US13555332
申请日：2012-07-23
申请人： Bhalchandra M. Karandikar , Carin J. Berg , Sophie Truc Lam , Sunita J. Macwana , Zhongju Liu Zhao
发明人： Bhalchandra M. Karandikar , Carin J. Berg , Sophie Truc Lam , Sunita J. Macwana , Zhongju Liu Zhao
IPC分类号： A01N39/00
CPC分类号： B01J23/34 , A61K33/00 , A61K33/32 , A61K33/40 , B01J35/0013 , B01J35/006 , B01J35/023 , C01B13/0211 , C01B13/0214 , A61K2300/00
摘要： There is provided on-demand, oxygen generating topical compositions having a built-in indicator specifically to indicate a color change upon the complete mixing of the oxygen precursor and catalyst. The first part of the composition contains a carrier and manganese dioxide (MnO2) nanoparticles. The second part of the composition comprises the oxygen precursor; hydrogen peroxide. When the two parts, one with manganese dioxide nanoparticles and exhibiting a characteristic color, (e.g. yellow brown) and the second part with hydrogen peroxide are mixed together, the color imparted by the manganese dioxide nanoparticles essentially disappears and the final composition (enriched with oxygen) either appears colorless or takes on the original color of the catalyst. Thus, the manganese dioxide catalyst nanoparticles themselves serve as the colorimetric indicator of peroxide decomposition to oxygen, precluding the need for an external colorant. Manganese dioxide particles that are not nanoparticles fail to exhibit this color changing phenomenon.
摘要翻译： 提供了按需氧气产生的局部组合物，其具有专门用于指示氧气前体和催化剂完全混合后的颜色变化的内置指示剂。 组合物的第一部分含有载体和二氧化锰（MnO 2）纳米颗粒。 组合物的第二部分包含氧前体; 过氧化氢。 当这两个部分，一个二氧化锰纳米粒子和具有特征颜色（例如黄棕色）和第二部分与过氧化氢混合在一起时，由二氧化锰纳米颗粒基本上消失的颜色和最终组成（富含氧气 ）呈现无色或呈现催化剂的原色。 因此，二氧化锰催化剂纳米颗粒本身用作过氧化物分解成氧的比色指示剂，排除了外部着色剂的需要。 不是纳米颗粒的二氧化锰颗粒不能显示出这种变色现象。
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公开(公告)号：US20130028983A1
公开(公告)日：2013-01-31
申请号：US13555332
申请日：2012-07-23
申请人： Bhalchandra M. Karandikar , Carin J. Berg , Sophie Truc Lam , Sunita J. Macwana , Zhongju Liu Zhao
发明人： Bhalchandra M. Karandikar , Carin J. Berg , Sophie Truc Lam , Sunita J. Macwana , Zhongju Liu Zhao
CPC分类号： B01J23/34 , A61K33/00 , A61K33/32 , A61K33/40 , B01J35/0013 , B01J35/006 , B01J35/023 , C01B13/0211 , C01B13/0214 , A61K2300/00
摘要： There is provided on-demand, oxygen generating topical compositions having a built-in indicator specifically to indicate a color change upon the complete mixing of the oxygen precursor and catalyst. The first part of the composition contains a carrier and manganese dioxide (MnO2) nanoparticles. The second part of the composition comprises the oxygen precursor; hydrogen peroxide. When the two parts, one with manganese dioxide nanoparticles and exhibiting a characteristic color, (e.g. yellow brown) and the second part with hydrogen peroxide are mixed together, the color imparted by the manganese dioxide nanoparticles essentially disappears and the final composition (enriched with oxygen) either appears colorless or takes on the original color of the catalyst. Thus, the manganese dioxide catalyst nanoparticles themselves serve as the colorimetric indicator of peroxide decomposition to oxygen, precluding the need for an external colorant. Manganese dioxide particles that are not nanoparticles fail to exhibit this color changing phenomenon.
摘要翻译： 提供了按需氧气产生的局部组合物，其具有专门用于指示氧气前体和催化剂完全混合后的颜色变化的内置指示剂。 组合物的第一部分含有载体和二氧化锰（MnO 2）纳米颗粒。 组合物的第二部分包含氧前体; 过氧化氢。 当这两个部分，一个二氧化锰纳米粒子和具有特征颜色（例如黄棕色）和第二部分与过氧化氢混合在一起时，由二氧化锰纳米颗粒基本上消失的颜色和最终组成（富含氧气 ）呈现无色或呈现催化剂的原色。 因此，二氧化锰催化剂纳米颗粒本身用作过氧化物分解成氧的比色指示剂，排除了外部着色剂的需要。 不是纳米颗粒的二氧化锰颗粒不能显示出这种变色现象。
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公开(公告)号：US20120240728A1
公开(公告)日：2012-09-27
申请号：US13070847
申请日：2011-03-24
申请人： John P. Gann , Sophie Truc Lam
发明人： John P. Gann , Sophie Truc Lam
CPC分类号： B22F9/24 , B22F2301/255 , B22F2303/01 , B22F2998/00 , C30B7/14 , C30B29/02 , C30B29/605 , B22F1/0025
摘要： A method of producing silver nanofilaments that is relatively fast and may be carried out at normal room temperatures (e.g., from about 10° C. to about 25° C.). The method of producing silver nanofilaments includes the steps of adding a solid silver salt to liquid ether to form a mixture, adding a liquid fatty acid to the mixture, adding a reducing agent to the mixture, allowing the ingredients to react, and recovering silver nanofilaments.
摘要翻译： 一种生产银纳米丝的方法，其相对较快并且可以在正常室温（例如约10℃至约25℃）下进行。 制造银纳米丝的方法包括以下步骤：将固体银盐加入到液体醚中以形成混合物，向混合物中加入液体脂肪酸，向混合物中加入还原剂，使成分反应，并回收银纳米丝 。
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公开(公告)号：US08475560B2
公开(公告)日：2013-07-02
申请号：US13070847
申请日：2011-03-24
申请人： John P. Gann , Sophie Truc Lam
发明人： John P. Gann , Sophie Truc Lam
CPC分类号： B22F9/24 , B22F2301/255 , B22F2303/01 , B22F2998/00 , C30B7/14 , C30B29/02 , C30B29/605 , B22F1/0025
摘要： A method of producing silver nanofilaments that is relatively fast and may be carried out at normal room temperatures (e.g., from about 10° C. to about 25° C.). The method of producing silver nanofilaments includes the steps of adding a solid silver salt to liquid ether to form a mixture, adding a liquid fatty acid to the mixture, adding a reducing agent to the mixture, allowing the ingredients to react, and recovering silver nanofilaments.
摘要翻译： 一种生产银纳米丝的方法，其相对较快并且可以在正常室温（例如约10℃至约25℃）下进行。 制造银纳米丝的方法包括以下步骤：将固体银盐加入到液体醚中以形成混合物，向混合物中加入液体脂肪酸，向混合物中加入还原剂，使成分反应，并回收银纳米丝 。
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