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公开(公告)号：US12084405B2
公开(公告)日：2024-09-10
申请号：US18500742
申请日：2023-11-02
发明人： Yong Moon Choi
IPC分类号： C07C271/12
CPC分类号： C07C271/12 , C07B2200/13
摘要： The present invention relates to crystalline forms of a phenyl carbamate derivative compound and compositions and uses thereof.
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公开(公告)号：US11795139B2
公开(公告)日：2023-10-24
申请号：US17837929
申请日：2022-06-10
发明人： Yong Moon Choi
IPC分类号： C07C271/16
CPC分类号： C07C271/16 , C07B2200/13
摘要： The present invention relates to a crystalline form of a phenyl carbamate derivative compound and a use thereof, and more particularly, to a more thermodynamically stable crystal, i.e., a Pattern 1 crystalline form, and a preparation method thereof. Amorphous and crystalline forms were prepared using various solvents, and among these, a thermodynamically stable Pattern 1 crystalline form and a pharmaceutical use of this crystalline form are provided.
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公开(公告)号：US09907776B2
公开(公告)日：2018-03-06
申请号：US14775037
申请日：2014-03-12
发明人： Yong Moon Choi
IPC分类号： A61K31/27 , A61K31/166 , A61K31/325 , C07C271/12 , C07C271/24
CPC分类号： A61K31/27 , A61K31/166 , A61K31/325 , C07C271/12 , C07C271/24 , C07C2601/02 , C07C2601/14 , C07C2602/42 , Y02A50/409
摘要： The present invention relates to a composition for preventing or treating a psychiatric disorder comprising a phenyl carbamate compound and a method for preventing or treating a psychiatric disorder therewith. The present invention provides anti-anxiety activity and protections against seizure and bipolar disorder, such that it may be effectively used for preventing or treating various psychiatric disorders related to mood disorder or resulting convulsion.
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4.发明授权公开(公告)号：US09682059B2
公开(公告)日：2017-06-20
申请号：US14775189
申请日：2014-03-11
发明人： Yong Moon Choi
IPC分类号： A61K31/325 , C07C271/12 , C07C271/24 , A61K31/03 , A61K31/27
CPC分类号： A61K31/325 , A61K31/03 , A61K31/27 , C07C271/12 , C07C271/24 , C07C2601/02 , C07C2601/14 , C07C2601/16 , C07C2602/42
摘要： The present invention provides a pharmaceutical composition for preventing and/or treating a epilepsy or epilepsy-related syndrome, for example an intractable epilepsy or its related syndrome such as drug-resistant epilepsy, comprising the phenyl carbamate compound as an active ingredient, and a use of the phenyl carbamate compound for preventing and/or treating epilepsy or epilepsy-related syndrome.
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5.发明授权Phenyl carbamate compound and a composition for preventing or treating a memory loss-related disease comprising the same 有权苯基氨基甲酸酯化合物和用于预防或治疗包含其的记忆丧失相关疾病的组合物公开(公告)号：US09566261B2
公开(公告)日：2017-02-14
申请号：US14774884
申请日：2014-03-12
发明人： Yong Moon Choi
IPC分类号： A61K31/045 , A61K31/27 , A61K31/166 , A61K31/325 , C07C271/12 , C07C271/24
CPC分类号： A61K31/27 , A61K31/166 , A61K31/325 , C07C271/12 , C07C271/24 , C07C2601/02 , C07C2601/14 , C07C2602/42 , Y02A50/409
摘要： The present invention relates to a composition for preventing or treating a memory loss related disease comprising a phenyl carbamate compound and a method for preventing or treating various diseases related to loss of memory therewith. The present invention ensures the enhancement of neuroprotection, such that it is promising for preventing or treating memory loss-related diseases such as dementia and Alzheimer's disease.
摘要翻译： 本发明涉及一种用于预防或治疗记忆丧失相关疾病的组合物，其包含苯基氨基甲酸酯化合物以及预防或治疗与其记忆丧失有关的各种疾病的方法。 本发明确保神经保护作用的增强，从而有希望预防或治疗诸如痴呆和阿尔茨海默氏病之类的记忆丧失相关疾病。
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6.发明授权Phenyl carbamate compound and a composition for preventing or treating a nerve gas-induced disease comprising the same 有权苯基氨基甲酸酯化合物和用于预防或治疗包含其的神经气体诱导疾病的组合物公开(公告)号：US09457003B2
公开(公告)日：2016-10-04
申请号：US14774891
申请日：2014-03-12
发明人： Yong Moon Choi
IPC分类号： A61K31/27 , A61K31/166 , A61K31/325 , C07C271/12 , C07C271/24
CPC分类号： A61K31/27 , A61K31/166 , A61K31/325 , C07C271/12 , C07C271/24 , C07C2601/02 , C07C2601/14 , C07C2602/42 , Y02A50/409
摘要： The present invention relates to a composition for preventing or treating a nerve gas-induced disease comprising a phenyl carbamate compound and a method for preventing or treating a nerve gas-induced disease therewith. The present invention ensures the enhancement of neuroprotection, such that it is promising for preventing or treating various diseases caused by exposure to nerve gas.
摘要翻译： 本发明涉及一种用于预防或治疗神经气体诱发疾病的组合物，其包含苯基氨基甲酸酯化合物以及用于预防或治疗神经性气体引起的疾病的方法。 本发明确保了神经保护的增强，从而有希望预防或治疗由于暴露于神经气体引起的各种疾病。
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公开(公告)号：US20130203846A1
公开(公告)日：2013-08-08
申请号：US13727661
申请日：2012-12-27
发明人： Yong Moon Choi
IPC分类号： C07C271/02 , C07C271/16
CPC分类号： C07C271/02 , A61K31/047 , A61K31/164 , A61K31/165 , A61K31/325 , C07C33/26 , C07C33/36 , C07C271/12 , C07C271/16 , C07C271/24 , C07C271/28 , C07C2601/02 , C07C2601/14 , C07C2602/42 , C07F7/1804
摘要： A composition for treating and/or preventing ALS containing the phenyl carbamate compound or a pharmaceutically acceptable salt thereof as an active ingredient; a method of treating and/or preventing ALS comprising administering the phenyl carbamate compound or a pharmaceutically acceptable salt thereof to a patient in need of ALS treatment; and a use of the phenyl carbamate compound or a pharmaceutically acceptable salt thereof in treating and/or preventing ALS, are provided.
摘要翻译： 用于治疗和/或预防含有苯基氨基甲酸酯化合物或其药学上可接受的盐的ALS作为活性成分的组合物; 治疗和/或预防ALS的方法，包括向需要ALS治疗的患者施用苯基氨基甲酸酯化合物或其药学上可接受的盐; 并提供了苯基氨基甲酸酯化合物或其药学上可接受的盐在治疗和/或预防ALS中的用途。
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公开(公告)号：US11896593B2
公开(公告)日：2024-02-13
申请号：US16980822
申请日：2020-09-10
发明人： Yong Moon Choi
IPC分类号： A61K31/506 , A61K31/357 , A61K31/381 , A61K31/427 , A61K31/445 , A61P25/24 , A61K31/443
CPC分类号： A61K31/506 , A61K31/357 , A61K31/381 , A61K31/427 , A61K31/443 , A61P25/24
摘要： The present invention relates to a pharmaceutical composition for treating and/or alleviating a psychiatric disorder comprising a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a pharmaceutical composition for inducing anti-stress, anti-anxiety and/or anti-depressant activities comprising a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient.
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公开(公告)号：US10525030B2
公开(公告)日：2020-01-07
申请号：US14774898
申请日：2014-03-12
发明人： Yong Moon Choi
IPC分类号： A61K31/325 , A61K31/27 , A61K31/166 , C07C271/12 , C07C271/24
摘要： The present invention relates to a composition for neuroprotection comprising a phenyl carbamate compound and a method for providing neuroprotection therewith. The present invention ensures the enhancement of neuroprotection, such that it is promising for preventing or treating various diseases associated with neurological injury.
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10.发明授权Phenyl alkyl carbamate compounds for use in preventing or treating epilepsy or epilepsy-related syndrome 有权用于预防或治疗癫痫或癫痫相关综合征的苯基烷基氨基甲酸酯化合物公开(公告)号：US09504668B2
公开(公告)日：2016-11-29
申请号：US14774287
申请日：2014-03-11
发明人： Yong Moon Choi
IPC分类号： A61K31/045 , A61K31/325 , C07C271/12 , C07C271/24 , A61K31/03 , A61K31/27
CPC分类号： A61K31/325 , A61K31/03 , A61K31/27 , C07C271/12 , C07C271/24 , C07C2601/02 , C07C2601/14 , C07C2601/16 , C07C2602/42
摘要： The present invention provides a pharmaceutical composition for preventing and/or treating a epilepsy or epilepsy-related syndrome, for example an intractable epilepsy or its related syndrome such as drug-resistant epilepsy, comprising the phenyl alkyl carbamate compound as an active ingredient, and a use of the phenyl alkyl carbamate compound for preventing and/or treating epilepsy or epilepsy-related syndrome.
摘要翻译： 本发明提供了用于预防和/或治疗癫痫或癫痫相关综合征的药物组合物，例如顽固性癫痫或其相关综合征，例如耐药性癫痫，其包含苯基烷基氨基甲酸酯化合物作为活性成分，以及 使用苯基烷基氨基甲酸酯化合物来预防和/或治疗癫痫或癫痫相关综合征。
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