公开(公告)号：US12006537B2

公开(公告)日：2024-06-11

申请号：US17855199

申请日：2022-06-30

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Duc Do ,  Claudia Litterst ,  Dianna Maar

IPC: C12Q1/68 ,  C12Q1/6844 ,  C12Q1/686 ,  G01N21/64

CPC classification number: C12Q1/686 ,  C12Q1/6844 ,  G01N21/6408

Abstract: Digital assay system, including methods, apparatus, and compositions, for assay of one or more targets in a set of partitions containing a generic reporter of target amplification.

公开(公告)号：US20140057273A1

公开(公告)日：2014-02-27

申请号：US13973940

申请日：2013-08-22

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Claudia Litterst ,  Austin P. So ,  Duc Do

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  C12Q1/6846 ,  C12Q1/6851 ,  C12Q1/6858 ,  C12Q2525/204 ,  C12Q2563/159

Abstract: Digital assay system, includes methods, apparatus, and compositions, for distinguishing and measuring different types of templates according to the different lengths of corresponding amplicons, which may be amplified by the same pair of primers. The system may include a length-sensitive reporter generating luminescence that varies according to amplicon length. The system may, for example, be utilized to identify, distinguish, and/or quantify wild-type and mutant/variant templates, processed and unprocessed template, a target template and a primer dimer, or the like.

Abstract translation: 数字测定系统包括用于根据相应扩增子的不同长度区分和测量不同类型的模板的方法，装置和组合物，其可以通过相同的引物对扩增。 该系统可以包括长度敏感的报告基因产生根据扩增子长度而变化的发光。 该系统可以例如用于鉴定，区分和/或定量野生型和突变体/变体模板，加工和未处理的模板，靶模板和引物二聚体等。

公开(公告)号：US11377684B2

公开(公告)日：2022-07-05

申请号：US15973243

申请日：2018-05-07

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Duc Do ,  Claudia Litterst ,  Dianna Maar

IPC: C12Q1/68 ,  C12Q1/686 ,  C12Q1/6844 ,  G01N21/64

Abstract: Digital assay system, including methods, apparatus, and compositions, for assay of one or more targets in a set of partitions containing a generic reporter of target amplification.

公开(公告)号：US20140178889A1

公开(公告)日：2014-06-26

申请号：US14191295

申请日：2014-02-26

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Duc Do ,  Claudia Litterst ,  Dianna Maar

IPC: C12Q1/68

CPC classification number: C12Q1/686 ,  C12Q1/6844 ,  G01N21/6408

Abstract: Digital assay system, including methods, apparatus, and compositions, for assay of one or more targets in a set of partitions containing a generic reporter of target amplification.

Abstract translation: 数字测定系统，包括方法，装置和组合物，用于在包含靶扩增的通用报告物的一组分区中测定一个或多个靶。

公开(公告)号：US09702822B2

公开(公告)日：2017-07-11

申请号：US13973940

申请日：2013-08-22

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Claudia Litterst ,  Austin P. So ,  Duc Do

IPC: C12Q1/68 ,  C12P19/34 ,  G01N21/64

CPC classification number: G01N21/6486 ,  C12Q1/6846 ,  C12Q1/6851 ,  C12Q1/6858 ,  C12Q2525/204 ,  C12Q2563/159

Abstract: Digital assay system, includes methods, apparatus, and compositions, for distinguishing and measuring different types of templates according to the different lengths of corresponding amplicons, which may be amplified by the same pair of primers. The system may include a length-sensitive reporter generating luminescence that varies according to amplicon length. The system may, for example, be utilized to identify, distinguish, and/or quantify wild-type and mutant/variant templates, processed and unprocessed template, a target template and a primer dimer, or the like.

公开(公告)号：US09970052B2

公开(公告)日：2018-05-15

申请号：US14191295

申请日：2014-02-26

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Duc Do ,  Claudia Litterst ,  Dianna Maar

IPC: C12Q1/68 ,  G01N21/64

CPC classification number: C12Q1/686 ,  C12Q1/6844 ,  G01N21/6408

Abstract: Digital assay system, including methods, apparatus, and compositions, for assay of one or more targets in a set of partitions containing a generic reporter of target amplification.

公开(公告)号：US20240279730A1

公开(公告)日：2024-08-22

申请号：US18654169

申请日：2024-05-03

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Duc Do ,  Claudia Litterst ,  Dianna Maar

IPC: C12Q1/686 ,  C12Q1/6844 ,  G01N21/64

CPC classification number: C12Q1/686 ,  C12Q1/6844 ,  G01N21/6408

Abstract: Digital assay system, including methods, apparatus, and compositions, for assay of one or more targets in a set of partitions containing a generic reporter of target amplification.