公开(公告)号：US08985808B2

公开(公告)日：2015-03-24

申请号：US13740590

申请日：2013-01-14

Applicant: Bio-Rad Laboratories, Inc.

Inventor： James W. Hillendahl ,  Evelio Perez

IPC: F21S4/00 ,  F21V21/005 ,  F21V9/08 ,  F21V13/02 ,  G01N21/64

CPC classification number: F21V21/005 ,  F21V9/083 ,  F21V13/02 ,  G01N21/255 ,  G01N21/6452 ,  G01N21/6456 ,  G01N27/447 ,  G01N2021/6463 ,  G01N2021/6471 ,  G01N2201/06 ,  G01N2201/0626 ,  G01N2201/0635

Abstract: A planar sample, particularly of the type used in biological laboratories for detection and sometimes analysis of two-dimensional arrays of proteins, nucleic acids, or other biological species, is illuminated by epi-illumination using optically filtered line lights that are arranged along opposing parallel sides of a rectangle in which the sample array resides, with two coaxial line lights on each side of the rectangle, and the two on any given side being separated by a gap whose optimal width depends on the wavelength band transmitted by the optical filter. Surprisingly, the gap eliminates the peak in intensity at the center of the sample area and the decrease that occurs from the center outward that would otherwise occur with a single continuous filtered line light, producing instead a substantially uniform intensity along the direction parallel to the line lights.

Abstract translation: 平面样品，特别是用于生物实验室中用于检测和有时分析蛋白质，核酸或其他生物物种的二维阵列的类型的样品，通过使用沿着相对的平行排列的光学滤波的线光照射外照射 样品阵列所在的矩形的边，在矩形的每一侧上具有两根同轴线灯，并且任意给定侧上的两根被间隔开，该间隙的最佳宽度取决于由滤光器传输的波长带。 令人惊奇的是，间隙消除了样品区域中心处的强度峰值以及从中心向外发生的减少，否则会出现与单个连续过滤线条光线相反的方向，沿着平行于该线条的方向产生基本均匀的强度 灯光

公开(公告)号：US20130223056A1

公开(公告)日：2013-08-29

申请号：US13740590

申请日：2013-01-14

Applicant: Bio-Rad Laboratories, Inc.

Inventor： James W. Hillendahl ,  Evelio Perez

IPC: F21V21/005 ,  F21V13/02 ,  F21V9/08

CPC classification number: F21V21/005 ,  F21V9/083 ,  F21V13/02 ,  G01N21/255 ,  G01N21/6452 ,  G01N21/6456 ,  G01N27/447 ,  G01N2021/6463 ,  G01N2021/6471 ,  G01N2201/06 ,  G01N2201/0626 ,  G01N2201/0635

Abstract: A planar sample, particularly of the type used in biological laboratories for detection and sometimes analysis of two-dimensional arrays of proteins, nucleic acids, or other biological species, is illuminated by epi-illumination using optically filtered line lights that are arranged along opposing parallel sides of a rectangle in which the sample array resides, with two coaxial line lights on each side of the rectangle, and the two on any given side being separated by a gap whose optimal width depends on the wavelength band transmitted by the optical filter. Surprisingly, the gap eliminates the peak in intensity at the center of the sample area and the decrease that occurs from the center outward that would otherwise occur with a single continuous filtered line light, producing instead a substantially uniform intensity along the direction parallel to the line lights.

Abstract translation: 平面样品，特别是用于生物实验室中用于检测和有时分析蛋白质，核酸或其他生物物种的二维阵列的类型的样品，通过使用沿着相对的平行排列的光学滤波的线光照射外照射 样品阵列所在的矩形的边，在矩形的每一侧上具有两根同轴线灯，并且任意给定侧上的两根被间隔开，该间隙的最佳宽度取决于由滤光器传输的波长带。 令人惊奇的是，间隙消除了样品区域中心处的强度峰值以及从中心向外发生的减少，否则会出现与单个连续过滤线条光线相反的方向，沿着平行于该线条的方向产生基本均匀的强度 灯光