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    Composition comprising the extract of actinidia arguta and related species for the prevention and treatment of allergic disease and non-allergic inflammatory disease
    5.
    发明申请
    Composition comprising the extract of actinidia arguta and related species for the prevention and treatment of allergic disease and non-allergic inflammatory disease 审中-公开
    包含猕猴桃提取物和相关物种的组合物，用于预防和治疗过敏性疾病和非过敏性炎性疾病

    公开(公告)号：US20070122508A1

    公开(公告)日：2007-05-31

    申请号：US11522511

    申请日：2006-09-18

    申请人： Sunyoung Kim ,  Eun Park ,  Bongcheol Kim ,  Mirim Jin ,  Hwa Lee

    发明人： Sunyoung Kim ,  Eun Park ,  Bongcheol Kim ,  Mirim Jin ,  Hwa Lee

    IPC分类号： A61K36/185

    CPC分类号： A23L33/105 ,  A23V2002/00 ,  A61K36/185 ,  A23V2250/70 ,  A23V2250/21 ,  A23V2250/72 ,  A23V2250/7056 ,  A23V2250/705 ,  A23V2250/156 ,  A23V2250/032 ,  A23V2250/28 ,  A23V2250/0644

    摘要： The present invention provides a pharmaceutical composition comprising the extract of hardy kiwifruit as an active ingredient in an effective amount to treat and prevent allergic disease and non-allergic inflammatory disease by reducing inflammation action, by inhibiting histamine release from mast cell, and by increasing the level of Th1 cytokines, IgG2a in serum and reducing the level of Th2 cytokines and IgE in serum. The present invention also provides a use of above extract for the preparation of pharmaceutical composition. The present invention also provides a health food or food additives, a cosmetic composition, a feed or feed additives comprising above extract for prevention or alleviation of allergic disease and non-allergic inflammatory disease by reducing inflammation action, by inhibiting histamine release from mast cell, and by increasing the level of Th1 cytokines, IgG2a in serum, and reducing the level of Th2 cytokines and IgE in serum.

    摘要翻译： 本发明提供一种药物组合物，其含有作为有效成分的强力猕猴桃提取物，通过抑制组织胺从肥大细胞释放而通过减少炎症作用，以及通过增加免疫反应来治疗和预防过敏性疾病和非变应性炎性疾病 血清中Th1细胞因子水平，IgG2a水平，降低血清中Th2细胞因子和IgE水平。 本发明还提供了上述提取物用于制备药物组合物的用途。 本发明还提供一种保健食品或食品添加剂，化妆品组合物，饲料或饲料添加剂，其包含通过抑制组织胺从肥大细胞释放而防止或减轻过敏性疾病和非变应性炎性疾病的上述提取物， 并通过增加血清中Th1细胞因子，IgG2a的水平，降低血清中Th2细胞因子和IgE的水平。