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公开(公告)号:US20220304842A1
公开(公告)日:2022-09-29
申请号:US17655958
申请日:2022-03-22
发明人: Daragh Nolan , Brian P. Watschke , Noel Smith , Moira B. Sweeney , Peter Fewer , Thomas Sinnott , Richard Percy , Natalie Ann Borgos , Eduardo Marcos Larangeira , John Gildea , Evania Ann Mareena
摘要: An implantable fluid operated device may include a fluid reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to transfer fluid between the fluid reservoir and the inflatable member. The pump assembly may include one or more fluid pumps and one or more valves. An electronic control system may control operation of the pump assembly based on fluid pressure measurements and/or fluid flow measurements received from the one or more sensing devices. The electronic control system may include an internal component installed with the implanted device, and an external component that is operable by a user to provide user input, and to receive output from the implanted device.
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公开(公告)号:US11786706B2
公开(公告)日:2023-10-17
申请号:US16783600
申请日:2020-02-06
CPC分类号: A61M25/10 , A61M31/00 , A61M37/0015 , A61M2025/105 , A61M2025/1013 , A61M2025/1086 , A61M2037/003 , A61M2037/0023 , A61M2037/0046 , A61M2037/0061
摘要: Devices and methods for delivering treatment fluids or particulates such as, stem cells, drugs, Botox and like, to an inner lining of a bladder for treatment of urinary tract disorders, including over-active bladder. A balloon delivery system can include an inflation balloon having a plurality of micro-needles configured to pierce and otherwise puncture an inner bladder wall so as to deliver the treatment fluid to bladder tissue. The treatment fluid can be directly injected into the bladder tissue using the micro needles. Alternatively, the micro needles can be fabricated of bioabsorbable or bioresorbable materials such that the micro needles can remain embedded within the bladder tissue to deliver the treatment fluid or particulate.
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3.
公开(公告)号:US20210299421A1
公开(公告)日:2021-09-30
申请号:US17301831
申请日:2021-04-15
发明人: Natalie Ann Borgos , Tania M. Schroeder , David J. Yonce , Robert E. Lund , Suranajan Roychowdhury
摘要: Systems and methods of localizing or delivery cells, biologics and/or drugs to a specific target area to treat pelvic health disorders are provided. A treatment composition including cells, biologics and/or drugs are associated with magnetic particulates, and the positioning of these materials is facilitated through use of a magnetic field-generating device that is configured to be placed on or into a pelvic anatomical structure. Certain embodiments directed to the treatment of ED in male patients can include a cell based therapy system.
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4.
公开(公告)号:US20170266425A1
公开(公告)日:2017-09-21
申请号:US15613664
申请日:2017-06-05
发明人: Natalie Ann Borgos , Tania M. Schroeder , David J. Yonce , Robert E. Lund , Suranajan Roychowdhury
CPC分类号: A61M35/003 , A61F5/41 , A61F2005/411 , A61F2005/418
摘要: Systems and methods of localizing or delivery cells, biologics and/or drugs to a specific target area to treat pelvic health disorders are provided. A treatment composition including cells, biologics and/or drugs are associated with magnetic particulates, and the positioning of these materials is facilitated through use of a magnetic field-generating device that is configured to be placed on or into a pelvic anatomical structure. Certain embodiments directed to the treatment of ED in male patients can include a cell based therapy system.
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公开(公告)号:US20160331502A1
公开(公告)日:2016-11-17
申请号:US15218720
申请日:2016-07-25
发明人: John R. Frigstad , Amanda J. Heys , Benjamin Y. Arcand , Natalie Ann Borgos , William A. Sturos , Daniel R. Parks
IPC分类号: A61F2/00
CPC分类号: A61F2/0045 , A61F2/0036 , A61F2/0063 , A61F2002/0068 , A61F2220/0033 , A61F2220/0083 , A61F2230/0019 , A61F2230/0069 , A61F2230/0078
摘要: Various embodiments of an implant system for treating fecal incontinence are provided. The devices and systems can include a mesh or like device that can include a variable porosity to control the degree of expansion of the anal canal. The mesh can be constructed at least in part of patterned strut members allowing for various geometric configurations, with varying load and tension properties for the designated portions of the device according to the needs for a particular patient application.
摘要翻译: 提供了用于治疗大便失禁的植入系统的各种实施例。 装置和系统可以包括可包括可变孔隙度以控制肛管扩张程度的网状物或类似装置。 网格可以至少部分地构造成图案化的支柱构件,其允许各种几何构型,根据特定患者应用的需要,针对装置的指定部分具有不同的负载和张力特性。
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公开(公告)号:US20200171280A1
公开(公告)日:2020-06-04
申请号:US16783600
申请日:2020-02-06
摘要: Devices and methods for delivering treatment fluids or particulates such as, stem cells, drugs, Botox and like, to an inner lining of a bladder for treatment of urinary tract disorders, including over-active bladder. A balloon delivery system can include an inflation balloon having a plurality of micro-needles configured to pierce and otherwise puncture an inner bladder wall so as to deliver the treatment fluid to bladder tissue. The treatment fluid can be directly injected into the bladder tissue using the micro needles. Alternatively, the micro needles can be fabricated of bioabsorbable or bioresorbable materials such that the micro needles can remain embedded within the bladder tissue to deliver the treatment fluid or particulate.
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公开(公告)号:US10426585B2
公开(公告)日:2019-10-01
申请号:US15218720
申请日:2016-07-25
发明人: John R. Frigstad , Amanda J. Heys , Benjamin Y. Arcand , Natalie Ann Borgos , William A. Sturos , Daniel R. Parks
IPC分类号: A61F2/00
摘要: Various embodiments of an implant system for treating fecal incontinence are provided. The devices and systems can include a mesh or like device that can include a variable porosity to control the degree of expansion of the anal canal. The mesh can be constructed at least in part of patterned strut members allowing for various geometric configurations, with varying load and tension properties for the designated portions of the device according to the needs for a particular patient application.
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8.
公开(公告)号:US10076647B2
公开(公告)日:2018-09-18
申请号:US15613664
申请日:2017-06-05
发明人: Natalie Ann Borgos , Tania M. Schroeder , David J. Yonce , Robert E. Lund , Suranajan Roychowdhury
CPC分类号: A61M35/003 , A61F5/41 , A61F2005/411 , A61F2005/418
摘要: Systems and methods of localizing or delivery cells, biologics and/or drugs to a specific target area to treat pelvic health disorders are provided. A treatment composition including cells, biologics and/or drugs are associated with magnetic particulates, and the positioning of these materials is facilitated through use of a magnetic field-generating device that is configured to be placed on or into a pelvic anatomical structure. Certain embodiments directed to the treatment of ED in male patients can include a cell based therapy system.
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公开(公告)号:US09675677B2
公开(公告)日:2017-06-13
申请号:US14931682
申请日:2015-11-03
发明人: Natalie Ann Borgos
CPC分类号: A61K38/4886 , A61K9/0019 , A61K9/0034 , A61K35/28 , A61K2300/00
摘要: The invention relates to systems and therapeutic methods to reduce plaque causing Peyronie's disease. One approach uses high pressure injection of collagenase-containing composition into a penile plaque. Plaque disruption is enhanced by the mechanical force of the high pressure, followed by the enzymatic action of collagenase. Another approach uses collagenase as a pretreatment, followed by addition of adipose-derived stem cells ADSCs. The initial collagenase injection breaks down collagen (often more type III than type I in Peyronie's) to provide short term benefit. The longer-term benefit is provided by introduction of ADSCs to the plaque, which can produce cytokines and other signals for revascularization, and restoration of normal penile tissue. The resulting combination advantageously reduces the bulk of the plaque early on with ongoing reduction through the revascularization of the tissue. In addition, the treatment provides an advantageous shift of elastin and collagen ratios.
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公开(公告)号:US20230414906A1
公开(公告)日:2023-12-28
申请号:US18465531
申请日:2023-09-12
CPC分类号: A61M25/10 , A61M37/0015 , A61M31/00 , A61M2037/0023 , A61M2037/0061 , A61M2025/1013 , A61M2025/1086 , A61M2037/003 , A61M2037/0046 , A61M2025/105
摘要: Devices and methods for delivering treatment fluids or particulates such as, stem cells, drugs, Botox and like, to an inner lining of a bladder for treatment of urinary tract disorders, including over-active bladder. A balloon delivery system can include an inflation balloon having a plurality of micro-needles configured to pierce and otherwise puncture an inner bladder wall so as to deliver the treatment fluid to bladder tissue. The treatment fluid can be directly injected into the bladder tissue using the micro needles. Alternatively, the micro needles can be fabricated of bioabsorbable or bioresorbable materials such that the micro needles can remain embedded within the bladder tissue to deliver the treatment fluid or particulate.
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