公开(公告)号：US06703531B2

公开(公告)日：2004-03-09

申请号：US10366611

申请日：2003-02-14

申请人： Boyapati M. Choudary ,  Naidu S. Chowdari ,  Mannepalli L. Kantam ,  Kondapuram V. Raghavan

发明人： Boyapati M. Choudary ,  Naidu S. Chowdari ,  Mannepalli L. Kantam ,  Kondapuram V. Raghavan

IPC分类号： C07C3326

CPC分类号： B01J31/1658 ,  B01J21/08 ,  B01J23/466 ,  B01J31/08 ,  B01J31/1608 ,  B01J31/165 ,  B01J31/1805 ,  B01J2231/32 ,  B01J2531/825 ,  C07B2200/07 ,  C07C29/48 ,  C07C31/20 ,  C07C33/24

摘要： The present invention discloses a process for the preparation of a novel heterogeneous osmate catalyst of the general formula (S—NR3)2OsO4.nH2O wherein S is a support, R is an alkyl group, n is the number of water molecules by reacting potassium osmate with supported quaternary ammonium species in an aqueous solvent.

摘要翻译： 本发明公开了一种制备通式（S-NR 3）2 O·4HH 2 O的新型异构锇酸酯催化剂的方法，其中S为支持物，R为烷基，n为锇酸钾反应的水分子数 在水性溶剂中具有负载的季铵物质。

公开(公告)号：US06552234B1

公开(公告)日：2003-04-22

申请号：US09983231

申请日：2001-10-23

申请人： Boyapati M. Choudary ,  Naidu S. Chowdari ,  Mannepalli L. Kantam ,  Kondapuram V. Raghavan

发明人： Boyapati M. Choudary ,  Naidu S. Chowdari ,  Mannepalli L. Kantam ,  Kondapuram V. Raghavan

IPC分类号： C07C3326

CPC分类号： B01J31/1658 ,  B01J21/08 ,  B01J23/466 ,  B01J31/08 ,  B01J31/1608 ,  B01J31/165 ,  B01J31/1805 ,  B01J2231/32 ,  B01J2531/825 ,  C07B2200/07 ,  C07C29/48 ,  C07C31/20 ,  C07C33/24

摘要： The present invention discloses a process for the preparation of a novel heterogeneous osmate catalyst of the general formula (S—NR3)2OsO4.nH2O wherein S is a support, R is an alkyl group, n is the number of water molecules by reacting potassium osmate with supported quaternary ammonium species in an aqueous solvent.

公开(公告)号：US06455735B1

公开(公告)日：2002-09-24

申请号：US09963785

申请日：2001-09-27

申请人： Boyapati M. Choudary ,  Balagam Bharathi ,  Mannepalli L. Kantam ,  Chinta R. V. Reddy ,  Kondapuram V. Raghavan

发明人： Boyapati M. Choudary ,  Balagam Bharathi ,  Mannepalli L. Kantam ,  Chinta R. V. Reddy ,  Kondapuram V. Raghavan

IPC分类号： C07C29104

CPC分类号： C07D265/30 ,  C07C291/04 ,  C07D211/94 ,  C07D217/08 ,  C07D295/24

摘要： The present invention provides a process for the preparation of high quality amine oxide by reacting a tertiary or secondary amine with hydrogen peroxide as an oxidant in presence of a recyclable heterogeneous layered double hydroxide exchanged with one of the anions of transition metal oxides as a catalyst in a solvent selected from the group consisting of water, water containing dodecylbenzenesulfonic acid sodium salt as additive, and a water miscible organic solvent.

摘要翻译： 本发明提供了通过使叔胺或仲胺与作为氧化剂的过氧化氢反应来制备高质量的氧化胺的方法，该可再循环的异质层状双氢氧化物与作为催化剂的过渡金属氧化物的阴离子之一交换 选自水，含有十二烷基苯磺酸钠盐的水作为添加剂的溶剂和水混溶性有机溶剂。

公开(公告)号：US06706901B1

公开(公告)日：2004-03-16

申请号：US10334119

申请日：2002-12-31

申请人： Boyapati M. Choudary ,  Naidu S. Chowdari ,  Sateesh Madhi ,  Lakshmi K. Mannepalli ,  Jyothi Karangula

发明人： Boyapati M. Choudary ,  Naidu S. Chowdari ,  Sateesh Madhi ,  Lakshmi K. Mannepalli ,  Jyothi Karangula

IPC分类号： C07D30514

CPC分类号： C07C231/10 ,  C07C233/87 ,  C07C247/12

摘要： The present invention relates to an improved process for the preparation of taxol side chain by synthesizing (2R,3S)-2,3-dihydroxy-3-phenylpropionate with greater than 99% enantioselectivity and devoid of osmium even in crude form in a single pot using a recyclable multifunctional catalysts, conversion of diol obtained without further crystallization into bromoacetate, reaction of bromoacetate with NaN3 in organic solvent followed by deacetylation with to obtain azido alcohol, benzoylation followed by hydrogenation of azido alcohol to obtain the (2R,3S)-(N-)-benzoyl-3-phenylisoserine methyl ester in 67% yield.

摘要翻译： 本发明涉及一种通过合成（2R，3S）-2,3-二羟基-3-苯基丙酸酯制备紫杉醇侧链的改进方法，其具有大于99％的对映选择性，甚至在单一罐中以粗制形式没有锇 使用可回收的多官能催化剂，将未经进一步结晶获得的二醇转化成溴乙酸酯，将溴乙酸酯与NaN 3在有机溶剂中反应，然后脱乙酰，得到叠氮醇，苯甲酰化，然后氢化叠氮醇，得到（2R，3S） - （ N - ） - 苯甲酰基-3-苯基异丝氨酸甲酯，收率67％。

公开(公告)号：US06881839B2

公开(公告)日：2005-04-19

申请号：US10334122

申请日：2002-12-31

申请人： Boyapati M. Choudary ,  Naidu S. Chowdari ,  Sateesh Madhi ,  Lakshmi K. Mannepalli

发明人： Boyapati M. Choudary ,  Naidu S. Chowdari ,  Sateesh Madhi ,  Lakshmi K. Mannepalli

IPC分类号： B01J23/04 ,  B01J23/30 ,  B01J23/44 ,  B01J31/08 ,  C07D281/10

CPC分类号： C07D281/10

摘要： The present invention comprises a simplified synthesis of (+)-diltiazem through IE-PdOsW wherein IE is ion-exchanger, catalyzed three-component coupling reaction and Fe3+-exchanged clay catalyzed ring opening of sulfite with 2-aminothiophenol followed by cyclization as key steps.

摘要翻译： 本发明包括通过IE-PdOsW的（+） - 地尔硫卓的简化合成，其中IE是离子交换剂，催化的三组分偶联反应和Fe 3+交换的粘土催化的亚硫酸盐开环与 2-氨基苯硫酚，然后环化作为关键步骤。