公开(公告)号：US20070077556A1

公开(公告)日：2007-04-05

申请号：US10106559

申请日：2002-03-25

申请人： Brad Nelson ,  Bradley Stone

发明人： Brad Nelson ,  Bradley Stone

IPC分类号： C12Q1/68 ,  G01N33/574

CPC分类号： G01N33/574 ,  G01N33/564 ,  G01N33/6854

摘要： The present invention provides methods and compositions for the diagnosis of hyperproliferative disease and autoimmune disease. Tumor associated antigens, nucleic acids encoding them and antibodies to the tumor associated antigens are provided for the diagnosis of hyperproliferative disease, such as, for example, ovarian cancer, breast cancer, lung cancer, colorectal cancer, and other epithelial cancers, and for the diagnosis of autoimmune disease.

摘要翻译： 本发明提供了用于诊断过度增殖性疾病和自身免疫疾病的方法和组合物。 肿瘤相关抗原，编码它们的核酸和与肿瘤相关抗原的抗体被提供用于诊断过度增殖性疾病，例如卵巢癌，乳腺癌，肺癌，结肠直肠癌和其它上皮癌，并且对于 诊断自身免疫性疾病。

公开(公告)号：US20080032316A1

公开(公告)日：2008-02-07

申请号：US11697639

申请日：2007-04-06

申请人： Brad Nelson ,  Bradley Stone

发明人： Brad Nelson ,  Bradley Stone

IPC分类号： G01N33/574

CPC分类号： G01N33/574 ,  G01N33/564 ,  G01N33/6854

摘要： The present invention provides methods and compositions for the diagnosis of hyperproliferative disease and autoimmune disease. Tumor associated antigens, nucleic acids encoding them and antibodies to the tumor associated antigens are provided for the diagnosis of hyperproliferative disease, such as, for example, ovarian cancer, breast cancer, lung cancer, colorectal cancer, and other epithelial cancers, and for the diagnosis of autoimmune disease.

摘要翻译： 本发明提供了用于诊断过度增殖性疾病和自身免疫疾病的方法和组合物。 肿瘤相关抗原，编码它们的核酸和与肿瘤相关抗原的抗体被提供用于诊断过度增殖性疾病，例如卵巢癌，乳腺癌，肺癌，结肠直肠癌和其它上皮癌，并且对于 诊断自身免疫性疾病。

公开(公告)号：US20050221305A1

公开(公告)日：2005-10-06

申请号：US10494874

申请日：2002-11-12

申请人： Brad Nelson ,  Bradley Stone

发明人： Brad Nelson ,  Bradley Stone

IPC分类号： A61K38/17 ,  A61K38/46 ,  A61K38/52 ,  C12Q1/68 ,  G01N33/564 ,  G01N33/574

CPC分类号： G01N33/57488 ,  C12Q1/6837 ,  C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/154 ,  C12Q2600/156 ,  C12Q2600/158 ,  G01N33/564 ,  G01N33/57449

摘要： The present invention provides methods and compositions for the diagnosis, prognosis and treatment of hyperproliferative disease and autoimmune disease. Tumor associated antigens, nucleic acids encoding them and antibodies to the tumor associated antigens are provided for the diagnosis, prognosis and treatment of hyperproliferative disease, such as, for example, ovarian cancer, breast cancer, lung cancer, colorectal cancer, and other epithelial cancers, and for the diagnosis, prognosis and treatment of autoimmune disease.

摘要翻译： 本发明提供了用于诊断，预后和治疗过度增殖性疾病和自身免疫疾病的方法和组合物。 提供肿瘤相关抗原，编码它们的核酸和抗肿瘤相关抗原的抗体，用于诊断，预后和治疗过度增殖性疾病，如卵巢癌，乳腺癌，肺癌，结肠直肠癌和其他上皮癌 ，以及自身免疫性疾病的诊断，预后和治疗。

公开(公告)号：US20070162841A1

公开(公告)日：2007-07-12

申请号：US11681642

申请日：2007-03-02

申请人： Wynn Bailey ,  Robert Lee ,  Jeffrey Jooste ,  Brad Nelson ,  Michael Olenick

发明人： Wynn Bailey ,  Robert Lee ,  Jeffrey Jooste ,  Brad Nelson ,  Michael Olenick

IPC分类号： G06F17/00 ,  G06F7/00

CPC分类号： G06F17/211 ,  G06F17/243 ,  G06Q20/045 ,  G06Q30/04 ,  G06Q40/04 ,  G07B1/00 ,  G07B5/04 ,  G07B2017/00201 ,  G07F17/42 ,  Y10S707/99943

摘要： A system and method for rapidly customizing and printing documents is disclosed. The system supports product lines having a plurality of customizable products therein, through the use of a single Web page that is continually updated in a data-driven fashion. The system is robust, easily expandable, and quickly deployable across a plurality of user platforms and geographic locations. Methods of the invention disclosed herein enable users to perform customization projects and to print the documents created thereby, either at a remote printer such as at a document factory, or at the user's own, local printer.

摘要翻译： 公开了一种用于快速定制和打印文档的系统和方法。 该系统通过使用以数据驱动方式不断更新的单个网页来支持其中具有多个可定制产品的产品线。 该系统在多个用户平台和地理位置可靠，易于扩展和快速部署。 本文公开的本发明的方法使得用户能够执行定制项目并且在诸如文档工厂的远程打印机处或在用户自己的本地打印机处打印由其创建的文档。

公开(公告)号：US08633754B2

公开(公告)日：2014-01-21

申请号：US13549018

申请日：2012-07-13

申请人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

发明人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

IPC分类号： H03L5/00

CPC分类号： H03L5/00 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/0603 ,  H01L2224/48091 ,  H01L2224/48137 ,  H01L2224/48247 ,  H01L2224/49112 ,  H01L2224/49113 ,  H01L2924/181 ,  H03H11/245 ,  H01L2924/00014 ,  H01L2924/00012

摘要： In one embodiment, a variable attenuator is disclosed having an attenuation circuit and a control circuit. The attenuation circuit may include a first series connected attenuation circuit segment and a shunt connected attenuation circuit segment, as well as additional attenuation circuit segments. Each attenuation circuit segment includes a stack of transistors that are coupled to provide the attenuation circuit segment with a variable impedance level having a continuous impedance range. In this manner, the control circuit may be operably associated with the stack of transistors in each attenuation circuit segment to control the variable attenuation level of the variable attenuator.

摘要翻译： 在一个实施例中，公开了一种具有衰减电路和控制电路的可变衰减器。 衰减电路可以包括第一串联连接的衰减电路段和分路连接的衰减电路段，以及附加的衰减电路段。 每个衰减电路段包括一堆晶体管，其被耦合以向衰减电路段提供具有连续阻抗范围的可变阻抗电平。 以这种方式，控制电路可以可操作地与每个衰减电路段中的晶体管堆叠相关联，以控制可变衰减器的可变衰减电平。

公开(公告)号：US20120280738A1

公开(公告)日：2012-11-08

申请号：US13549018

申请日：2012-07-13

申请人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

发明人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

IPC分类号： H03L5/00 ,  H01L21/58

CPC分类号： H03L5/00 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/0603 ,  H01L2224/48091 ,  H01L2224/48137 ,  H01L2224/48247 ,  H01L2224/49112 ,  H01L2224/49113 ,  H01L2924/181 ,  H03H11/245 ,  H01L2924/00014 ,  H01L2924/00012

摘要： In one embodiment, a variable attenuator is disclosed having an attenuation circuit and a control circuit. The attenuation circuit may include a first series connected attenuation circuit segment and a shunt connected attenuation circuit segment, as well as additional attenuation circuit segments. Each attenuation circuit segment includes a stack of transistors that are coupled to provide the attenuation circuit segment with a variable impedance level having a continuous impedance range. In this manner, the control circuit may be operably associated with the stack of transistors in each attenuation circuit segment to control the variable attenuation level of the variable attenuator.

摘要翻译： 在一个实施例中，公开了一种具有衰减电路和控制电路的可变衰减器。 衰减电路可以包括第一串联连接的衰减电路段和分路连接的衰减电路段，以及附加的衰减电路段。 每个衰减电路段包括一堆晶体管，其被耦合以向衰减电路段提供具有连续阻抗范围的可变阻抗电平。 以这种方式，控制电路可以可操作地与每个衰减电路段中的晶体管堆叠相关联，以控制可变衰减器的可变衰减电平。

公开(公告)号：US20110148502A1

公开(公告)日：2011-06-23

申请号：US12978149

申请日：2010-12-23

申请人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

发明人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

IPC分类号： H03L5/00

CPC分类号： H03L5/00 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/0603 ,  H01L2224/48091 ,  H01L2224/48137 ,  H01L2224/48247 ,  H01L2224/49112 ,  H01L2224/49113 ,  H01L2924/181 ,  H03H11/245 ,  H01L2924/00014 ,  H01L2924/00012

摘要： In one embodiment, a temperature compensating attenuator is disclosed having an attenuation circuit and a control circuit. The temperature compensating attenuator circuit may include a first series connected attenuation circuit segment and a shunt connected attenuation circuit segment, as well as additional attenuation circuit segments. Each attenuation circuit segment includes a stack of transistors that are coupled to provide the attenuation circuit segment with an impedance attenuation level having a continuous impedance range. The control circuit may be operably associated with the stack of transistors in each attenuation circuit segment to control the attenuation level of the attenuation circuit. The temperature compensating attenuator includes a temperature compensating circuit that compensates for variations in operation of the attenuation circuit due to a temperature change.

摘要翻译： 在一个实施例中，公开了具有衰减电路和控制电路的温度补偿衰减器。 温度补偿衰减器电路可以包括第一串联连接的衰减电路段和分流连接的衰减电路段，以及附加的衰减电路段。 每个衰减电路段包括一堆晶体管，其被耦合以向衰减电路段提供具有连续阻抗范围的阻抗衰减电平。 控制电路可以可操作地与每个衰减电路段中的晶体管堆叠相关联，以控制衰减电路的衰减电平。 温度补偿衰减器包括温度补偿电路，其补偿由于温度变化引起的衰减电路的工作变化。

公开(公告)号：US20110148501A1

公开(公告)日：2011-06-23

申请号：US12977958

申请日：2010-12-23

申请人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

发明人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

IPC分类号： H03H11/02

CPC分类号： H03L5/00 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/0603 ,  H01L2224/48091 ,  H01L2224/48137 ,  H01L2224/48247 ,  H01L2224/49112 ,  H01L2224/49113 ,  H01L2924/181 ,  H03H11/245 ,  H01L2924/00014 ,  H01L2924/00012

摘要： In one embodiment, a variable attenuator is disclosed having an attenuation circuit and a control circuit. The attenuation circuit may include a first series connected attenuation circuit segment and a shunt connected attenuation circuit segment, as well as additional attenuation circuit segments. Each attenuation circuit segment includes a stack of transistors that are coupled to provide the attenuation circuit segment with a variable impedance level having a continuous impedance range. In this manner, the control circuit may be operably associated with the stack of transistors in each attenuation circuit segment to control the variable attenuation level of the variable attenuator.

摘要翻译： 在一个实施例中，公开了一种具有衰减电路和控制电路的可变衰减器。 衰减电路可以包括第一串联连接的衰减电路段和分路连接的衰减电路段，以及附加的衰减电路段。 每个衰减电路段包括一堆晶体管，其被耦合以向衰减电路段提供具有连续阻抗范围的可变阻抗电平。 以这种方式，控制电路可以可操作地与每个衰减电路段中的晶体管堆叠相关联，以控制可变衰减器的可变衰减电平。

公开(公告)号：US08334718B2

公开(公告)日：2012-12-18

申请号：US12977958

申请日：2010-12-23

申请人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

发明人： Marcus Granger-Jones ,  Brad Nelson ,  Ed Franzwa

IPC分类号： H03H11/02

CPC分类号： H03L5/00 ,  H01L2224/05553 ,  H01L2224/05554 ,  H01L2224/0603 ,  H01L2224/48091 ,  H01L2224/48137 ,  H01L2224/48247 ,  H01L2224/49112 ,  H01L2224/49113 ,  H01L2924/181 ,  H03H11/245 ,  H01L2924/00014 ,  H01L2924/00012

摘要： In one embodiment, a variable attenuator is disclosed having an attenuation circuit and a control circuit. The attenuation circuit may include a first series connected attenuation circuit segment and a shunt connected attenuation circuit segment, as well as additional attenuation circuit segments. Each attenuation circuit segment includes a stack of transistors that are coupled to provide the attenuation circuit segment with a variable impedance level having a continuous impedance range. In this manner, the control circuit may be operably associated with the stack of transistors in each attenuation circuit segment to control the variable attenuation level of the variable attenuator.

摘要翻译： 在一个实施例中，公开了一种具有衰减电路和控制电路的可变衰减器。 衰减电路可以包括第一串联连接的衰减电路段和分路连接的衰减电路段，以及附加的衰减电路段。 每个衰减电路段包括一堆晶体管，其被耦合以向衰减电路段提供具有连续阻抗范围的可变阻抗电平。 以这种方式，控制电路可以可操作地与每个衰减电路段中的晶体管堆叠相关联，以控制可变衰减器的可变衰减电平。

公开(公告)号：US20090018907A1

公开(公告)日：2009-01-15

申请号：US11776150

申请日：2007-07-11

申请人： Patrick J. McCarthy ,  David E. Barousse, JR. ,  Luke Walsh ,  Brad Nelson ,  Joseph P. Garstka ,  Charles Brian O'Kelley

发明人： Patrick J. McCarthy ,  David E. Barousse, JR. ,  Luke Walsh ,  Brad Nelson ,  Joseph P. Garstka ,  Charles Brian O'Kelley

IPC分类号： G06Q30/00

CPC分类号： G06Q30/08 ,  G06Q30/02 ,  G06Q30/0247 ,  G06Q30/0275 ,  G06Q30/0277

摘要： There are methods and apparatus, including computer program products, for receiving an ad call from a client computing system, determining whether an instance of the ad call was previously-received, and if so, designating a first ad creative supplier associated with the previous instance of the ad call as ineligible to participate in an auction in which a second ad creative supplier is selected to serve an ad creative responsive to the ad call.

摘要翻译： 有一些方法和装置，包括计算机程序产品，用于从客户端计算系统接收广告呼叫，确定是否先前接收到广告呼叫的实例，如果是，则指定与先前实例相关联的第一个广告创意供应商 的广告呼叫不符合参与拍卖的选择，其中第二广告创意供应商被选择以响应于该广告呼叫来投放广告创意。