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    Database and imaging processing system and methods for analyzing images acquired using an image acquisition system
    1.
    发明授权
    Database and imaging processing system and methods for analyzing images acquired using an image acquisition system 有权
    用于分析使用图像采集系统获取的图像的数据库和成像处理系统和方法

    公开(公告)号：US09177102B2

    公开(公告)日：2015-11-03

    申请号：US13459866

    申请日：2012-04-30

    申请人： Bradley A. Bower ,  Eric L. Buckland ,  Kenneth W. Chapman ,  Igor Touzov

    发明人： Bradley A. Bower ,  Eric L. Buckland ,  Kenneth W. Chapman ,  Igor Touzov

    IPC分类号： G06K9/00 ,  G06F19/00 ,  G06T7/00 ,  A61B3/10

    CPC分类号： G06F19/321 ,  A61B3/102 ,  G06F19/00 ,  G06T7/0012 ,  G06T2207/10101 ,  G06T2207/30041

    摘要： Methods are provided including receiving a plurality of images from at least one image acquisition system; selecting at least a portion of a set of images for analysis using at least one attribute of image metadata; selecting at least one method for deriving quantitative information from the at least a portion of the set of images; processing the selected at least a portion of the set of images with the selected at least one method for deriving quantitative information; associating the derived quantitative information with the at least a portion of the set of images via a data structure; selecting at least one method for aggregating at least a portion of a set of derived quantitative information into a reduced set of results; and generating at least one report to represent the reduced set of results for one of an individual image and the set of images as a pool.

    摘要翻译： 提供了包括从至少一个图像采集系统接收多个图像的方法; 使用图像元数据的至少一个属性来选择一组图像的至少一部分用于分析; 从所述图像集合的至少一部分中选择用于导出定量信息的至少一种方法; 用所选择的用于导出定量信息的至少一种方法来处理所选择的图像集合的至少一部分; 通过数据结构将导出的定量信息与该组图像的至少一部分相关联; 选择至少一种用于将一组导出的定量信息的至少一部分聚合成一组减少的结果的方法; 以及生成至少一个报告，以将个体图像中的一个图像和所述图像集合的缩小的结果集合表示为池。

    Image Analysis System and Related Methods and Computer Program Products
    2.
    发明申请
    Image Analysis System and Related Methods and Computer Program Products 有权
    图像分析系统及相关方法及计算机程序产品

    公开(公告)号：US20120275677A1

    公开(公告)日：2012-11-01

    申请号：US13459866

    申请日：2012-04-30

    申请人： Bradley A. Bower ,  Eric L. Buckland ,  Kenneth W. Chapman ,  Igor Touzov

    发明人： Bradley A. Bower ,  Eric L. Buckland ,  Kenneth W. Chapman ,  Igor Touzov

    IPC分类号： G06K9/00

    CPC分类号： G06F19/321 ,  A61B3/102 ,  G06F19/00 ,  G06T7/0012 ,  G06T2207/10101 ,  G06T2207/30041

    摘要： Methods are provided including receiving a plurality of images from at least one image acquisition system; selecting at least a portion of a set of images for analysis using at least one attribute of image metadata; selecting at least one method for deriving quantitative information from the at least a portion of the set of images; processing the selected at least a portion of the set of images with the selected at least one method for deriving quantitative information; associating the derived quantitative information with the at least a portion of the set of images via a data structure; selecting at least one method for aggregating at least a portion of a set of derived quantitative information into a reduced set of results; and generating at least one report to represent the reduced set of results for one of an individual image and the set of images as a pool.

    摘要翻译： 提供了包括从至少一个图像采集系统接收多个图像的方法; 使用图像元数据的至少一个属性来选择一组图像的至少一部分用于分析; 从所述图像集合的至少一部分中选择用于导出定量信息的至少一种方法; 用所选择的用于导出定量信息的至少一种方法来处理所选择的图像集合的至少一部分; 通过数据结构将导出的定量信息与该组图像的至少一部分相关联; 选择至少一种用于将一组导出的定量信息的至少一部分聚合成一组减少的结果的方法; 以及生成至少一个报告，以将个体图像中的一个图像和所述图像集合的缩小的结果集合表示为池。

    Compact multimodality optical coherence tomography imaging systems
    5.
    发明授权
    Compact multimodality optical coherence tomography imaging systems 有权
    紧凑型多模光学相干断层成像系统

    公开(公告)号：US08896842B2

    公开(公告)日：2014-11-25

    申请号：US13198117

    申请日：2011-08-04

    申请人： Bradley A. Bower ,  Robert H. Hart ,  Pete Huening ,  Eric L. Buckland

    发明人： Bradley A. Bower ,  Robert H. Hart ,  Pete Huening ,  Eric L. Buckland

    IPC分类号： G01B9/02 ,  A61B3/10 ,  A61B3/14

    CPC分类号： A61B3/102 ,  A61B3/14 ,  G01B9/0203 ,  G01B9/02091

    摘要： Systems for imaging a sample are provided. The system includes an optical coherence tomography (OCT) imaging portion having an associated OCT path defined by one set of optical elements between an OCT signal delivery optical fiber and the sample; an image capture portion having an associated image capture path defined by a second set of optical elements between an image capture device and the sample, different from the OCT path; and an illuminator portion having an associated illumination path defined by a third set of optical elements between an illumination source and the sample. The OCT path, the image capture path, and the illuminator path have at least one optical element in common, and the respective paths differ from each other by at least one optical element. The OCT path and the image capture path share a common intermediate conjugate image plane. Focal control is achieved for the OCT path and the image capture path concurrently through adjustment of one or more common optical elements distal to the common intermediate conjugate plane, such that focal control requires no differential adjustment between optical elements not in common to both paths.

    摘要翻译： 提供了用于成像样本的系统。 该系统包括光学相干断层摄影（OCT）成像部分，其具有由OCT信号传送光纤和样本之间的一组光学元件限定的相关OCT路径; 图像捕获部分，具有由图像捕获装置和样本之间的不同于OCT路径的第二组光学元件定义的相关联的图像捕获路径; 以及具有由照明源和样品之间的第三组光学元件限定的相关联的照明路径的照明器部分。 OCT路径，图像捕获路径和照明器路径具有共同的至少一个光学元件，并且相应的路径由至少一个光学元件彼此不同。 OCT路径和图像捕获路径共享一个共同的中间共轭图像平面。 通过调整远离公共中间共轭平面的一个或多个共同的光学元件，通过同时进行OCT路径和图像捕获路径的焦点控制，使得焦点控制不需要在两个路径不共同的光学元件之间进行差分调整。

    Methods, systems and computer program products for biometric identification by tissue imaging using optical coherence tomography (OCT)
    6.
    发明授权
    Methods, systems and computer program products for biometric identification by tissue imaging using optical coherence tomography (OCT) 有权
    使用光学相干断层扫描（OCT）进行组织成像生物识别的方法，系统和计算机程序产品

    公开(公告)号：US08687856B2

    公开(公告)日：2014-04-01

    申请号：US12624937

    申请日：2009-11-24

    申请人： Bradley A. Bower ,  Eric L. Buckland

    发明人： Bradley A. Bower ,  Eric L. Buckland

    IPC分类号： G06K9/00

    CPC分类号： G06K9/00006 ,  G06K9/00087 ,  G06K9/00362

    摘要： Optical coherence tomography (OCT) imaging systems for imaging uniquely identifiable structure are provided including a source having an associated source arm path and having an associated reference arm path coupled to the source path, the reference arm path having an associated reference arm path length. A sample having an associated sample arm path coupled to the source arm and reference arm paths is provided. Processing methods to convert the depth-dependent image data to a uniquely identifiable code are provided. Related methods and computer program products are also provided.

    摘要翻译： 提供用于成像唯一可识别结构的光学相干断层摄影（OCT）成像系统，包括具有相关联的源臂路径并具有耦合到源路径的相关联的参考臂路径的源，参考臂路径具有相关联的参考臂路径长度。 提供具有耦合到源臂和参考臂路径的相关联的样本臂路径的样本。 提供了将深度相关图像数据转换为唯一可识别代码的处理方法。 还提供了相关方法和计算机程序产品。

    Compact Multimodality Optical Coherence Tomography Imaging Systems and Related Methods and Computer Program Products
    8.
    发明申请
    Compact Multimodality Optical Coherence Tomography Imaging Systems and Related Methods and Computer Program Products 有权
    紧凑多模光学相干断层扫描成像系统及相关方法和计算机程序产品

    公开(公告)号：US20120033227A1

    公开(公告)日：2012-02-09

    申请号：US13198117

    申请日：2011-08-04

    申请人： Bradley A. Bower ,  Robert H. Hart ,  Pete Huening ,  Eric L. Buckland

    发明人： Bradley A. Bower ,  Robert H. Hart ,  Pete Huening ,  Eric L. Buckland

    IPC分类号： G01B9/02

    CPC分类号： A61B3/102 ,  A61B3/14 ,  G01B9/0203 ,  G01B9/02091

    摘要： Systems for imaging a sample are provided. The system includes an optical coherence tomography (OCT) imaging portion having an associated OCT path defined by one set of optical elements between an OCT signal delivery optical fiber and the sample; an image capture portion having an associated image capture path defined by a second set of optical elements between an image capture device and the sample, different from the OCT path; and an illuminator portion having an associated illumination path defined by a third set of optical elements between an illumination source and the sample. The OCT path, the image capture path, and the illuminator path have at least one optical element in common, and the respective paths differ from each other by at least one optical element. The OCT path and the image capture path share a common intermediate conjugate image plane. Focal control is achieved for the OCT path and the image capture path concurrently through adjustment of one or more common optical elements distal to the common intermediate conjugate plane, such that focal control requires no differential adjustment between optical elements not in common to both paths.

    摘要翻译： 提供了用于成像样本的系统。 该系统包括光学相干断层摄影（OCT）成像部分，其具有由OCT信号传送光纤和样本之间的一组光学元件限定的相关OCT路径; 图像捕获部分，具有由图像捕获装置和样本之间的不同于OCT路径的第二组光学元件定义的相关联的图像捕获路径; 以及具有由照明源和样品之间的第三组光学元件限定的相关联的照明路径的照明器部分。 OCT路径，图像捕获路径和照明器路径具有共同的至少一个光学元件，并且相应的路径由至少一个光学元件彼此不同。 OCT路径和图像捕获路径共享一个共同的中间共轭图像平面。 通过调整远离公共中间共轭平面的一个或多个共同的光学元件，通过同时进行OCT路径和图像捕获路径的焦点控制，使得焦点控制不需要在两个路径不共同的光学元件之间进行差分调整。

    Methods, Systems and Computer Program Products for Diagnosing Conditions Using Unique Codes Generated from a Multidimensional Image of a Sample
    9.
    发明申请
    Methods, Systems and Computer Program Products for Diagnosing Conditions Using Unique Codes Generated from a Multidimensional Image of a Sample 有权
    方法，系统和计算机程序产品，用于使用从样本的多维图像生成的唯一代码来诊断条件

    公开(公告)号：US20110160576A1

    公开(公告)日：2011-06-30

    申请号：US12953868

    申请日：2010-11-24

    申请人： Bradley A. Bower ,  Eric L. Buckland

    发明人： Bradley A. Bower ,  Eric L. Buckland

    IPC分类号： A61B6/00

    CPC分类号： G06K9/00604 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/117 ,  A61B5/1171 ,  A61B5/6821 ,  A61B5/6826 ,  G06K7/1413 ,  G06K7/1417 ,  G06K7/1447 ,  G06K9/00033 ,  G06K9/0008 ,  G06K9/00892 ,  G06T11/006

    摘要： Methods of providing a diagnosis using a digital code associated with an image are provided including collecting a multidimensional image, the multidimensional image having at least two dimensions; extracting a two dimensional subset of the multidimensional image; reducing the multidimensional image to a first code that is unique to the multidimensional image based on the extracted two dimensional image; comparing the first unique code associated with the subject to a library of reference codes, each of the reference codes in the library of reference codes being indicative of a class of objects; determining if the subject associated with the first unique code falls into at least one of the classes of objects associated with the reference codes based on a result of the comparison; and formulating a diagnostic decision based on the whether the first unique code associated with the subject falls into at least one of the classes associated with the reference code. Related systems and computer program products are also provided herein.

    摘要翻译： 提供使用与图像相关联的数字代码提供诊断的方法，包括收集多维图像，所述多维图像具有至少两个维度; 提取多维图像的二维子集; 将所述多维图像减少为基于所提取的二维图像对于所述多维图像是唯一的第一代码; 将与主题相关联的第一唯一代码与参考代码库进行比较，参考代码库中的每个参考代码指示一类对象; 基于比较的结果，确定与第一唯一码相关联的被摄体是否落入与参考码相关联的对象类别中的至少一个中; 以及基于与所述对象相关联的所述第一唯一代码是否落入与所述参考代码相关联的类别中的至少一个中来制定诊断决策。 本文还提供了相关系统和计算机程序产品。