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    Apparatus and method for ultrasonic medical device with improved visibility in imaging procedures
    1.
    发明授权
    Apparatus and method for ultrasonic medical device with improved visibility in imaging procedures 失效
    超声波医疗设备的装置和方法，具有改进的成像过程中的可见性

    公开(公告)号：US06730048B1

    公开(公告)日：2004-05-04

    申请号：US10328202

    申请日：2002-12-23

    申请人： Bradley A. Hare ,  Janniah S. Prasad

    发明人： Bradley A. Hare ,  Janniah S. Prasad

    IPC分类号： A61B1722

    CPC分类号： A61B17/22012 ,  A61B90/39 ,  A61B2017/00902 ,  A61B2017/22014 ,  A61B2017/22018 ,  A61B2090/3925

    摘要： The present invention provides an apparatus and method for an ultrasonic medical device with improved visibility in imaging procedures. A medical device comprises an elongated probe having a material of high radiopacity at an at least one predetermined location of the probe wherein the material of high radiopacity is capable of withstanding series of vibrations of the elongated probe. The material of high radiopacity allows the elongated probe to be visualized in imaging procedures when the probe is inserted into a body. The present invention provides a method of improving the visibility of an ultrasonic medical device during a medical procedure by engaging a material of high radiopacity to a small diameter elongated probe wherein the material of high radiopacity engages the probe at an at least one predetermined location.

    摘要翻译： 本发明提供一种超声波医疗装置的装置和方法，其具有改进的成像过程中的可见性。 医疗装置包括在探针的至少一个预定位置处具有高射线不透性材料的细长探针，其中高不透射线材料能够承受细长探针的一系列振动。 高射线不透射线的材料允许细长的探针在成像过程中可视化，当探针插入体内时。 本发明提供了一种在医疗过程中通过将高辐射不透性材料接合到小直径细长探针来提高超声波医疗装置的可视性的方法，其中高射线不透性材料在至少一个预定位置处接合探针。

    Method for manufacturing small diameter medical devices
    2.
    发明授权
    Method for manufacturing small diameter medical devices 失效
    小直径医疗器械的制造方法

    公开(公告)号：US06647755B2

    公开(公告)日：2003-11-18

    申请号：US10092862

    申请日：2002-03-06

    申请人： Robert A. Rabiner ,  Bradley A. Hare ,  Janniah S. Prasad

    发明人： Robert A. Rabiner ,  Bradley A. Hare ,  Janniah S. Prasad

    IPC分类号： B21C128

    CPC分类号： B21C3/02 ,  A61B17/22012 ,  A61B2017/22015 ,  A61B2017/22018 ,  B21C1/22 ,  B21C1/30 ,  B21C9/02 ,  B21F45/008

    摘要： An apparatus and method for manufacturing small diameter ultrasonic probes capable of vibrating in a transverse mode that can be used in ultrasonic tissue ablation. The apparatus includes a die, a style puller which is used to engage a functional end of the medical device, and a die room puller which is used to draw the medical device through the die. The die includes a bell-shaped lead-in on a front side of the die and a bell-shaped lead-in on a back side of the die allowing for reversal of the direction of the draw. The method of manufacturing includes heat treating a large diameter medical device, drawing the large diameter device through a die and reversing the draw of the medical device through the die to provide a medical device having a varying diameter along a length of the device. The method is repeated until a final diameter is reached.

    摘要翻译： 一种用于制造能够用于超声波组织消融的横向模式的小直径超声波探头的装置和方法。 该装置包括模具，用于接合医疗装置的功能端的型式拔出器，以及用于通过模具拉出医疗装置的模具室拉拔器。 模具包括在模具的前侧上的钟形引导件和在模具的背面上的钟形引入件，从而能够反转拉伸方向。 制造方法包括对大直径医疗装置进行热处理，通过模具拉伸大直径装置并使医疗装置通过模头反转，以提供具有沿装置长度变化的直径的医疗装置。 重复该方法直到达到最终直径。

    APPARATUS AND METHOD FOR AN ULTRASONIC MEDICAL DEVICE WITH VARIABLE FREQUENCY DRIVE
    4.
    发明申请
    APPARATUS AND METHOD FOR AN ULTRASONIC MEDICAL DEVICE WITH VARIABLE FREQUENCY DRIVE 审中-公开
    具有可变频率驱动的超声医疗装置的装置和方法

    公开(公告)号：US20100087759A1

    公开(公告)日：2010-04-08

    申请号：US12555495

    申请日：2009-09-08

    申请人： Bradley A. Hare ,  Kyle K. Jarger ,  Charles J. Vadala, JR. ,  Anthony W. O'Leary ,  Thomas A. Murphy ,  Roy M. Robertson

    发明人： Bradley A. Hare ,  Kyle K. Jarger ,  Charles J. Vadala, JR. ,  Anthony W. O'Leary ,  Thomas A. Murphy ,  Roy M. Robertson

    IPC分类号： A61N7/00

    CPC分类号： A61B17/22012 ,  A61B2017/22014 ,  A61B2017/320098

    摘要： An apparatus and method for an ultrasonic medical device with a variable frequency drive for ablating a biological material comprises an ultrasonic probe having a proximal end, a distal end and a longitudinal axis therebetween; a transducer that drives the ultrasonic probe over a variable frequency range, creating a transverse ultrasonic vibration along at least a portion of the longitudinal axis of the ultrasonic probe; a coupling engaging the proximal end of the ultrasonic probe to a distal end of the transducer; and an ultrasonic energy source engaged to the transducer that produces an ultrasonic energy, wherein driving the ultrasonic probe over the variable frequency range allows for the ultrasonic energy to propagate around a bend of the ultrasonic probe to ablate the biological material in communication with the ultrasonic probe.

    摘要翻译： 一种具有用于烧蚀生物材料的变频驱动器的超声波医疗装置的装置和方法包括：超声波探头，其具有近端，远端和在其间的纵向轴线; 换能器，其在可变频率范围内驱动超声波探头，沿着超声波探头的纵轴的至少一部分产生横向超声波振动; 将所述超声波探头的近端接合到所述换能器的远端的联接器; 以及接合到所述换能器的超声波能源，其产生超声波能量，其中在所述可变频率范围上驱动所述超声波探头允许所述超声能量围绕所述超声波探头的弯曲部传播以消融与所述超声波探头连通的所述生物材料 。

    Ultrasonic medical device operating in a transverse mode
    5.
    发明授权
    Ultrasonic medical device operating in a transverse mode 有权
    超声波医疗器械以横向模式工作

    公开(公告)号：US07494468B2

    公开(公告)日：2009-02-24

    申请号：US10371781

    申请日：2003-02-21

    申请人： Robert A. Rabiner ,  Bradley A. Hare ,  David M. Fischer ,  Andy Levine

    发明人： Robert A. Rabiner ,  Bradley A. Hare ,  David M. Fischer ,  Andy Levine

    IPC分类号： A61B8/00 ,  A61B17/32

    CPC分类号： A61N7/022 ,  A61B17/22012 ,  A61B17/320068 ,  A61B2017/00137 ,  A61B2017/00274 ,  A61B2017/22002 ,  A61B2017/22007 ,  A61B2017/22008 ,  A61B2017/22015 ,  A61B2017/22018 ,  A61B2017/22051 ,  A61B2017/293 ,  A61B2017/320084 ,  A61B2018/00547 ,  A61B2018/00982 ,  A61B2217/005 ,  A61B2217/007 ,  A61N2007/0008

    摘要： An ultrasonic medical device comprises an ultrasonic vibration generator that generates vibration along its longitudinal axis. The ultrasonic vibration is transmitted through an ultrasonic coupler and a series of transformer sections that amplify the ultrasonic vibration. A flexible member is coupled to the distal end of the transformer sections, and is thus supplied with a longitudinal vibration at its base by the transformer sections. The flexible member is designed so that it converts the longitudinal vibration into a standing wave that runs along the length of the flexible member. The standing wave produces a series of nodes and anti-nodes along the length of the flexible member. Each of the anti-nodes produces cavitation in fluids in contact with the probe. The cavitation of the fluids causes destruction of adjacent tissue. In this manner, the entire length of the flexible member becomes a working surface that may be utilized for destroying tissue.

    摘要翻译： 超声波医疗装置包括沿其纵向轴线产生振动的超声波振动发生器。 超声波振动通过超声波耦合器和一系列扩大超声波振动的变压器部分传播。 柔性构件联接到变压器部分的远端，并且因此在其底部由变压器部分提供纵向振动。 柔性构件被设计成使得其将纵向振动转换成沿着柔性构件的长度延伸的驻波。 驻波在柔性构件的长度上产生一系列节点和反节点。 每个反节点在与探针接触的流体中产生气蚀。 流体的气蚀导致相邻组织的破坏。 以这种方式，柔性构件的整个长度变成可用于破坏组织的工作表面。

    Ultrasonic probe device with rapid attachment and detachment means
    6.
    发明授权
    Ultrasonic probe device with rapid attachment and detachment means 有权
    超声波探头装置具有快速的附着和拆卸手段

    公开(公告)号：US06695782B2

    公开(公告)日：2004-02-24

    申请号：US09975725

    申请日：2001-10-11

    申请人： Kevin Ranucci ,  Robert A. Rabiner ,  Bradley A. Hare ,  Mark J. Varady ,  Rebecca I. Marciante ,  Roy Robertson

    发明人： Kevin Ranucci ,  Robert A. Rabiner ,  Bradley A. Hare ,  Mark J. Varady ,  Rebecca I. Marciante ,  Roy Robertson

    IPC分类号： A61N700

    CPC分类号： A61B17/320068 ,  A61B17/22012 ,  A61B2017/00137 ,  A61B2017/00274 ,  A61B2017/00477 ,  A61B2017/22007 ,  A61B2017/22008 ,  A61B2017/22018 ,  A61B2017/320084 ,  A61B2018/00547 ,  A61N7/022 ,  A61N2007/0008

    摘要： An ultrasonic tissue ablation device comprising a transversely vibrating elongated probe, and a coupling assembly for probe attachment detachment that enables the probe assembly and separation from the device body that includes the ultrasound energy source and a sound conductor, and a method of use for removal of vascular occlusions in blood vessels. The coupling assembly enables incorporation of elongated probes with small cross sectional lumens such as a catheter guidewires. The probe detachability allows insertion manipulation and withdrawal independently of the device body. The probe can be used with acoustic and/or aspirations sheaths to enhance destruction and removal of an occlusion. The horn assembly of the device that contains a sound conducting horn functions as an energy regulator and reservoir for the probe, and precludes loss of probe cavitation energy by its bending or damping within the blood vessel.

    摘要翻译： 一种超声波组织消融装置，其包括横向振动的细长探针和用于探针附接分离的联接组件，其使探针组装和分离从包括超声波能量的装置主体和声导体，以及用于去除 血管中的血管闭塞。 联接组件使得能够结合具有小横截面流明的细长探针，例如导管导丝。 探头可拆卸性允许独立于设备主体的插入操作和取出。 探头可以与声学和/或吸气鞘一起使用，以增强咬合的破坏和去除。 包含传导喇叭的装置的喇叭组件用作探针的能量调节器和储存器，并且通过其在血管内的弯曲或阻尼来排除探针空化能量的损失。

    Ultrasonic medical device for tissue remodeling
    7.
    发明授权
    Ultrasonic medical device for tissue remodeling 有权
    超声波医疗器械用于组织重塑

    公开(公告)号：US06695781B2

    公开(公告)日：2004-02-24

    申请号：US09917471

    申请日：2001-07-27

    申请人： Robert A. Rabiner ,  Bradley A. Hare

    发明人： Robert A. Rabiner ,  Bradley A. Hare

    IPC分类号： A61N700

    CPC分类号： A61B17/320068 ,  A61B2017/00137 ,  A61B2017/00274 ,  A61B2017/00477 ,  A61B2017/22007 ,  A61B2017/22008 ,  A61B2017/22018 ,  A61B2017/320084 ,  A61B2018/00547 ,  A61N7/022 ,  A61N2007/0008

    摘要： A method for destructing, reducing or removing mammalian tissue with an ultrasonic device IS disclosed, comprising contacting the tissue with a transverse mode ultrasonic probe, and transmitting ultrasonic energy to the probe, until the tissue is fragmented by emulsification. The probe can be used with acoustic and/or aspirations sheaths to enhance destruction and removal of an occlusion and in combination with an imaging device to effect remodeling of human tissue in medical and cosmetic surgical procedures.

    摘要翻译： 公开了一种用超声波装置IS破坏，减少或去除哺乳动物组织的方法，包括使组织与横向模式超声波探头接触，并将超声波能量传递给探针，直到组织被乳化分裂为止。 探针可以与声学和/或吸气鞘一起使用以增强咬合的破坏和去除，并与成像装置组合以在医疗和美容外科手术中实现人体组织的重塑。

    Dispensation and disposal container for medical devices
    8.
    发明授权
    Dispensation and disposal container for medical devices 失效

    公开(公告)号：US06527115B2

    公开(公告)日：2003-03-04

    申请号：US09775908

    申请日：2001-02-02

    申请人： Robert A. Rabiner ,  Bradley A. Hare ,  James H. Loper

    发明人： Robert A. Rabiner ,  Bradley A. Hare ,  James H. Loper

    IPC分类号： B65D8310

    CPC分类号： B65D43/20 ,  A61B50/30 ,  A61B50/36 ,  A61B2050/0081 ,  A61M5/3213

    摘要： The invention is directed to a container for storage, dispensation, transport and disposal of a medical device such a disposable ultrasonic surgical probe, that allows its dispensation for use, and for its safe storage and disposal after use, thereby protecting the user from the hazards of needle pricks and possible contamination from small-diameter probes. The container of the present invention also provides a mechanism for restricting access to the probe to prevent its reuse, and a method for its safe attachment to and detachment from an ultrasonic medical device. The container comprises a cylindrical tube having two ends and an inner surface defining a space for containing the probe. The probe is held within the cylindrical section of the container by a locking means that allows a single dispensation for its use and enables its disposal after use in an inaccessible manner, so as to enable its attachment and detachment to the non-disposable segment of the device such as an ultrasonic probe handle without requiring direct handling by the user. The user, is therefore protected from against accidental sticks from a possibly contaminated probe. The container also prevents re-use of the probe, and provides a means for its safe disposal.