公开(公告)号：US10561527B2

公开(公告)日：2020-02-18

申请号：US15171858

申请日：2016-06-02

申请人： BrainCool AB

发明人： Allan Rozenberg ,  Denise Barbut ,  John K Hoffman ,  Thomas H Shaffer

IPC分类号： A61F7/12 ,  A61M15/08 ,  A61M25/00 ,  A61K31/02 ,  A61M16/04 ,  A61K9/00 ,  A61K47/06 ,  A61M25/10 ,  A61M31/00 ,  A61F7/00

摘要： Devices for cerebral and systemic cooling via a patient's nasopharyngeal cavity are described. Cooling assemblies include at least one elongate tubular member having first and second lumens, a source of liquid coolant, a gas source communicating with the first lumen, and a switch for alternately connecting the liquid coolant source to the second lumen. The first lumen transports a compressed gas and the second lumen transports a volatile liquid. The pressurized fluid may be a perfluorocarbon. The perfluorocarbon may be perfluorohexane, perfluoropentane, or 2-methyl-perfluoropentane. The gas may be air, oxygen, or a combination.

公开(公告)号：US09775741B2

公开(公告)日：2017-10-03

申请号：US14266600

申请日：2014-04-30

申请人： BrainCool AB

发明人： Denise Barbut ,  Alan Rozenberg ,  John K Hoffman ,  Thomas H Shaffer

IPC分类号： A61F7/10 ,  A61F7/12 ,  A61K31/02 ,  A61M15/08 ,  A61M25/00 ,  A61F7/00 ,  A61M16/04 ,  A61M25/10 ,  A61M31/00 ,  A61M16/10

CPC分类号： A61F7/10 ,  A61F7/12 ,  A61F7/123 ,  A61F2007/0002 ,  A61F2007/0063 ,  A61F2007/0064 ,  A61F2007/0065 ,  A61F2007/0069 ,  A61K31/02 ,  A61M15/08 ,  A61M15/085 ,  A61M16/04 ,  A61M16/0409 ,  A61M16/0438 ,  A61M16/0454 ,  A61M16/0479 ,  A61M16/0486 ,  A61M16/107 ,  A61M25/003 ,  A61M25/0032 ,  A61M25/0068 ,  A61M25/007 ,  A61M25/1011 ,  A61M31/00 ,  A61M2025/0034 ,  A61M2025/0036 ,  A61M2025/0073

摘要： Methods for cerebral cooling are described. Cooling assemblies include elongate tubular members, a reservoir containing a pressurized fluid, and a manifold connecting the reservoir and elongate tubular members. After insertion of the elongate tubular members into the patient's nostrils, a pressurized fluid is delivered onto a surface of the patient's nasal cavity through a plurality of ports in the elongate tubular members. The delivery of the fluid causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis.