公开(公告)号：US20060264636A1

公开(公告)日：2006-11-23

申请号：US10554367

申请日：2004-04-22

申请人： Braj Lohray ,  Vidya Lohray ,  Mayank Dave

发明人： Braj Lohray ,  Vidya Lohray ,  Mayank Dave

IPC分类号： A61K31/4743 ,  C07D498/02

CPC分类号： C07D495/04

摘要： Disclosed are new salts of Clopidogrel viz. Clopidogrel mesylate, Clopidogrel besylate and Clopidogrel tosylate, methods for their preparation and pharmaceutical compositions containing them and their use in medicine.

摘要翻译： 公开了氯吡格雷的新盐 甲磺酸氯吡格雷，苯磺酸氯吡格雷和甲磺酸氯吡格雷，其制备方法和含有它们的药物组合物及其在医学中的应用。

公开(公告)号：US20070037842A1

公开(公告)日：2007-02-15

申请号：US10548712

申请日：2003-03-12

申请人： Braj Lohray ,  Vidya Lohray ,  Bipin Pandey ,  Mayank Dave

发明人： Braj Lohray ,  Vidya Lohray ,  Bipin Pandey ,  Mayank Dave

IPC分类号： A61K31/4743 ,  C07D498/02

CPC分类号： C07D495/04

摘要： The present invention relates to new polymorphs of S-(+)-Clopidogrel bisulfate and a process for preparing the same.

摘要翻译： 本发明涉及S - （+） - 氯吡格雷硫酸氢盐的新型多晶型物及其制备方法。

公开(公告)号：US20060089500A1

公开(公告)日：2006-04-27

申请号：US11296749

申请日：2005-12-07

申请人： Ranga Gurram ,  Venkateswarlu Akella ,  Rajagopalan Ramanujam ,  Ranjan Chakrabarti ,  Parimal Misra ,  Vidya Lohray ,  Braj Lohray ,  Rao Paraselli

发明人： Ranga Gurram ,  Venkateswarlu Akella ,  Rajagopalan Ramanujam ,  Ranjan Chakrabarti ,  Parimal Misra ,  Vidya Lohray ,  Braj Lohray ,  Rao Paraselli

IPC分类号： A61K31/513 ,  C07D239/02

CPC分类号： C07D239/36 ,  C07C217/22 ,  C07C237/32 ,  C07C247/04 ,  C07D239/90

摘要： The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel β-aryl-α-oxysubstituted alkylcarboxylic acids of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds, their analogs, their derivatives, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to novel intermediates, processes for their preparation and their use in the preparation of compounds of formula (I).

公开(公告)号：US20070275994A1

公开(公告)日：2007-11-29

申请号：US10559628

申请日：2004-06-04

申请人： Braj Lohray ,  Vidya Lohray ,  Brijesh Srivastava

发明人： Braj Lohray ,  Vidya Lohray ,  Brijesh Srivastava

IPC分类号： A61K31/4365 ,  A61K31/4355 ,  A61P31/00 ,  C07D471/04

CPC分类号： C07D495/04 ,  C07D491/04

摘要： The present invention describes novel antiinfective compounds of formula (I), process for their preparation and pharmaceutical compositions containing them.

摘要翻译： 本发明描述了式（I）的新型抗感染化合物，其制备方法和含有它们的药物组合物。

公开(公告)号：US20060270683A1

公开(公告)日：2006-11-30

申请号：US10554366

申请日：2004-04-22

申请人： Braj Lohray ,  Vidya Lohray ,  Kaushik Sata

发明人： Braj Lohray ,  Vidya Lohray ,  Kaushik Sata

IPC分类号： A61K31/496 ,  C07D403/02

CPC分类号： C07D401/12

摘要： The present invention relates to new polymorphs of Aripiprazole, process for their preparation, pharmaceutical compositions containing them and their use.

摘要翻译： 本发明涉及阿立哌唑的新型多晶型物，其制备方法，含有它们的药物组合物及其用途。

公开(公告)号：US20060229316A1

公开(公告)日：2006-10-12

申请号：US10509892

申请日：2003-03-26

申请人： Braj Lohray ,  Vidya Lohray ,  Brijesh Srivastava

发明人： Braj Lohray ,  Vidya Lohray ,  Brijesh Srivastava

IPC分类号： A61K31/496 ,  C07D413/02

CPC分类号： C07D263/20 ,  A61K31/422 ,  A61K31/497 ,  C07D413/12

摘要： The present invention describes novel antiinfective compounds, process for their preparation and pharmaceutical compositions containing them.

摘要翻译： 本发明描述了新颖的抗感染化合物，其制备方法和含有它们的药物组合物。

公开(公告)号：US20080004446A1

公开(公告)日：2008-01-03

申请号：US11896911

申请日：2007-09-06

申请人： Bipin Pandey ,  Vidya Lohray ,  Braj Lohray

发明人： Bipin Pandey ,  Vidya Lohray ,  Braj Lohray

IPC分类号： C07D417/12

CPC分类号： C07D213/30 ,  C07D213/34 ,  C07D417/12

摘要： A process for preparing thiazolidinediones, preferably pioglitazone, is described. Also described are intermediates involved in synthesizing thiazolidinediones, and processes for preparation and use in medicine.

摘要翻译： 描述了制备噻唑烷二酮类，优选吡格列酮的方法。 还描述了涉及合成噻唑烷二酮类的中间体，以及药物制备和应用的方法。

公开(公告)号：US20060167061A1

公开(公告)日：2006-07-27

申请号：US10520166

申请日：2003-07-15

申请人： Bipin Pandey ,  Vidya Lohray ,  Braj Lohray

发明人： Bipin Pandey ,  Vidya Lohray ,  Braj Lohray

IPC分类号： A61K31/4439 ,  C07D417/02

CPC分类号： C07D213/30 ,  C07D213/34 ,  C07D417/12

摘要： A novel process for preparing thiazolidinediones, preferably Pioglitazone, as described. Also described are novel intermediates involved in its synthesis and process for their preparation and use in medicine.

摘要翻译： 如所述制备噻唑烷二酮类，优选吡格列酮的新方法。 还描述了涉及其合成的新型中间体及其在医药中的制备和应用的方法。

公开(公告)号：US20080051386A1

公开(公告)日：2008-02-28

申请号：US11632236

申请日：2005-07-08

申请人： Braj Lohray ,  Vidya Lohray ,  Brijesh Srivastava

发明人： Braj Lohray ,  Vidya Lohray ,  Brijesh Srivastava

IPC分类号： A61K31/416 ,  A61K31/4162 ,  A61P43/00 ,  C07D231/54 ,  C07D495/04 ,  C07D495/14

CPC分类号： C07D495/14 ,  C07D495/04

摘要： The present invention relates to novel compounds of general formula (I), their regioisomers, tautomeric forms, novel intermediates involved in their synthesis. The present invention also relates to a process of preparing compounds of general formula (I), their regioisomers, their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis.

摘要翻译： 本发明涉及通式（I）的新型化合物，其区域异构体，互变异构体，涉及其合成的新型中间体。 本发明还涉及制备通式（I）的化合物，其区域异构体，其互变异构形式，其药学上可接受的盐，含有它们的药物组合物以及参与其合成的新中间体的方法。

公开(公告)号：US20070275956A1

公开(公告)日：2007-11-29

申请号：US10576130

申请日：2004-10-14

申请人： Braj Lohray ,  Vidya Lohray

发明人： Braj Lohray ,  Vidya Lohray

IPC分类号： A61K31/54 ,  A61K31/535 ,  A61P3/00 ,  A61P9/00 ,  C07D265/00 ,  C07D279/22

CPC分类号： C07D207/325 ,  C07D207/333 ,  C07D209/08 ,  C07D209/86 ,  C07D213/30 ,  C07D213/36 ,  C07D213/74 ,  C07D215/06 ,  C07D235/06 ,  C07D235/12 ,  C07D239/42 ,  C07D239/56 ,  C07D239/90 ,  C07D249/18 ,  C07D261/08 ,  C07D263/14 ,  C07D263/24 ,  C07D263/32 ,  C07D263/56 ,  C07D265/36 ,  C07D265/38 ,  C07D277/64 ,  C07D279/16 ,  C07D279/22 ,  C07D279/26 ,  C07D295/088 ,  C07D401/04 ,  C07D405/04 ,  C07D409/04 ,  C07D413/04 ,  C07D471/04 ,  C07D495/04

摘要： Disclosed are novel compounds of formula (I, having hypolipidaemic and hypocholesterolemic properties, their tautomeric forms, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.

摘要翻译： 公开了具有降血脂和降血胆固醇性质的新的式（I）化合物，其互变异构形式，其药学上可接受的盐，其药学上可接受的溶剂合物和含有它们的药学上可接受的组合物。