公开(公告)号：US20220008918A1

公开(公告)日：2022-01-13

申请号：US16316193

申请日：2017-07-07

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Rustem F. ISMAGILOV ,  Travis S. SCHLAPPI ,  Stephanie E. MCCALLA ,  Nathan G. SCHOEPP

IPC: B01L3/00 ,  C12Q1/686 ,  B01L7/00

Abstract: Methods and devices for detecting a low concentration analyte in a sample are provided herein. The methods include flowing a sample through a porous membrane coated with a capture matrix to capture the low concentration analyte. The methods also can include detecting the captured analyte, such as by performing in-situ amplification of the analyte.

公开(公告)号：US20210301326A1

公开(公告)日：2021-09-30

申请号：US17164674

申请日：2021-02-01

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Rustem F. ISMAGILOV ,  Nathan G. SCHOEPP ,  Emily S. SAVELA ,  Eric J. LIAW ,  Alexander WINNETT ,  Matthew M. COOPER

IPC: C12Q1/689

Abstract: Provided herein is an antibiotic susceptibility test and related compositions, methods and systems based on detection of a nucleic acid from a target microorganism in a sample in the presence or absence of a lysis treatment of the sample.

公开(公告)号：US20180274020A1

公开(公告)日：2018-09-27

申请号：US15524449

申请日：2015-11-05

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  SLIPCHIP CORPORATION

Inventor： Rustem F. ISMAGILOV ,  Eugenia KHOROSHEVA ,  Travis S. SCHLAPPI ,  Matthew S. CURTIS ,  Nathan G. SCHOEPP ,  Hedia MAAMAR ,  Feng SHEN ,  Erik B. JUE

IPC: C12Q1/6851 ,  C12Q1/686 ,  C12Q1/689 ,  C12Q1/18 ,  B01L7/00 ,  B01L3/00

CPC classification number: C12Q1/6851 ,  B01L3/502715 ,  B01L7/00 ,  B01L2300/0861 ,  C12Q1/18 ,  C12Q1/6809 ,  C12Q1/686 ,  C12Q1/689 ,  C12Q2600/136 ,  C12Q2600/158 ,  C12Q2537/165 ,  C12Q2545/114 ,  C12Q2565/629

Abstract: Disclosed herein are methods and devices for rapid assessment of whether a microorganism present in a sample is susceptible or resistant to a treatment.