公开(公告)号：US20180105859A1

公开(公告)日：2018-04-19

申请号：US15715086

申请日：2017-09-25

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Rustem F. Ismagilov ,  Nathan G. Schoepp ,  Travis S. Schlappi ,  Matthew S. Curtis

IPC: C12Q1/18 ,  G01N33/58 ,  C12Q1/6851 ,  G01N33/569

CPC classification number: C12Q1/18 ,  C12Q1/10 ,  C12Q1/6851 ,  G01N33/56938 ,  G01N33/582 ,  C12Q2527/101 ,  C12Q2537/165

Abstract: Disclosed herein are methods and devices for using digital isothermal amplification to detect subtle responses to environmental stimuli, such as detecting antibiotic susceptibility using digital quantification of DNA replication and/or chromosome segregation.

公开(公告)号：US11542545B2

公开(公告)日：2023-01-03

申请号：US15524449

申请日：2015-11-05

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  Talis Biomedical Corporation

Inventor： Rustem F. Ismagilov ,  Eugenia Khorosheva ,  Travis S. Schlappi ,  Matthew S. Curtis ,  Nathan G. Schoepp ,  Hedia Maamar ,  Feng Shen ,  Erik B. Jue

IPC: C12Q1/6851 ,  C12Q1/689 ,  C12Q1/6809 ,  C12Q1/18 ,  C12Q1/686 ,  B01L3/00 ,  B01L7/00

Abstract: Disclosed herein are methods and devices for rapid assessment of whether a microorganism present in a sample is susceptible or resistant to a treatment.

公开(公告)号：US11168347B2

公开(公告)日：2021-11-09

申请号：US15715086

申请日：2017-09-25

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Rustem F. Ismagilov ,  Nathan G. Schoepp ,  Travis S. Schlappi ,  Matthew S. Curtis

IPC: C12Q1/18 ,  C12Q1/6851 ,  C12Q1/10

Abstract: Disclosed herein are methods and devices for using digital isothermal amplification to detect subtle responses to environmental stimuli, such as detecting antibiotic susceptibility using digital quantification of DNA replication and/or chromosome segregation.