公开(公告)号：US20190233484A1

公开(公告)日：2019-08-01

申请号：US16210539

申请日：2018-12-05

申请人： CELERA CORPORATION

发明人： Elizabeth Joseloff ,  Steve Ruben ,  Tao He

IPC分类号： C07K14/47 ,  C07K14/435 ,  C07K16/18 ,  C12Q1/6876 ,  G01N33/53 ,  C12Q1/6886 ,  C12N15/113 ,  C07K16/30 ,  G01N33/574

CPC分类号： C07K14/47 ,  A61K2039/505 ,  C07K14/435 ,  C07K16/18 ,  C07K16/3038 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/734 ,  C07K2317/92 ,  C12N15/113 ,  C12N2310/14 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N33/53 ,  G01N33/57438 ,  G01N33/57484 ,  G01N2333/47 ,  G01N2500/00 ,  G01N2500/10 ,  Y10T436/143333

摘要： The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney.