公开(公告)号：US09662350B2

公开(公告)日：2017-05-30

申请号：US14452836

申请日：2014-08-06

申请人： CHINA MEDICAL UNIVERSITY

发明人： Feng-Huei Lin ,  Teng-Le Huang ,  Horng-Chaung Hsu ,  Chun-Hsu Yao ,  Yueh-Sheng Chen ,  Wen-Yu Su

IPC分类号： A61K31/728 ,  A61K9/00 ,  A61K31/355 ,  A61K31/375 ,  A61K31/59 ,  A61K47/02

CPC分类号： A61K31/728 ,  A61K9/0019 ,  A61K31/355 ,  A61K31/375 ,  A61K31/59 ,  A61K47/02 ,  A61K2300/00

摘要： A pharmaceutical composition for inhibiting inflammation is provided. The pharmaceutical composition comprises (a) hyaluronic acid, (b) a vitamin and (c) a pharmaceutically acceptable carrier.

公开(公告)号：US20230012279A1

公开(公告)日：2023-01-12

申请号：US17854229

申请日：2022-06-30

申请人： China Medical University

发明人： Cherng-Jyh Ke ,  Feng-Huei Lin ,  Chun-Hsu Yao ,  Jui-Sheng Sun ,  Ching-Yun Chen

IPC分类号： A61K38/45 ,  A61K9/06 ,  A61K47/42 ,  A61K47/34 ,  A61K31/728 ,  A61K47/02 ,  A61K47/18 ,  A61K35/19 ,  A61K35/16 ,  A61K38/36

摘要： A hydrogel composition, a hydrogel biomedical material, a method for facilitating regeneration of a bone and a manufacturing method of a hydrogel composition are provided. The hydrogel composition includes a first deionized water, a gel powder, a transglutaminase mixture and a hyaluronic acid powder. The gel powder includes gelatin and alginic acid. The first deionized water, the gel powder, the transglutaminase mixture and the hyaluronic acid powder are evenly mixed. Based on the hydrogel composition being 100 wt %, the first deionized water is 95 wt % to 98.46 wt %, the gel powder is 1 wt % to 3 wt %, the transglutaminase mixture is 0.04 wt % to 0.15 wt %, and the hyaluronic acid powder is 0.5 wt % to 1.5 wt %.

公开(公告)号：US20200339936A1

公开(公告)日：2020-10-29

申请号：US16856203

申请日：2020-04-23

申请人： China Medical University

发明人： Dan-Jae Lin ,  Ming-Tzu Tsai ,  Chao-Wei Hung ,  Yi-Tao Chang ,  Chun-Hsu Yao

IPC分类号： C12M1/42 ,  C12M1/00 ,  C12M1/34

摘要： A cell mechanical stimulating device for applying to at least one cell sample is provided. The device includes a base unit, at least one moving component and at least one magnetic component. The base unit includes a base body and a separating lid. The base body includes at least one culturing chamber and a bottom chamber surface. The cell sample is disposed in the culturing chamber, and the separating lid encloses the culturing chamber. The magnetic component drives the moving component to shift between a pressurizing position and a non-pressurizing position. At the pressurizing position, the moving component moves toward the bottom chamber surface and pressurizes the cell sample. At the non-pressurizing position, the moving component moves toward the separating lid and the pressure on the cell sample is removed. The cell sample is pressurized by the magnetic component driving the moving component.