公开(公告)号：US20240229006A1

公开(公告)日：2024-07-11

申请号：US17914306

申请日：2021-03-24

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Eun Bin Yang ,  Cheol Woong Ha ,  Yeonsoo Kim ,  Yeong Eun Im

IPC: C12N9/00 ,  C12N15/81 ,  C12P21/02

CPC classification number: C12N9/93 ,  C12N15/81 ,  C12P21/02 ,  C12Y603/02002

Abstract: Provided are a novel glutamate-cysteine ligase variant and a method of producing glutathione using the same.

公开(公告)号：US20220387532A1

公开(公告)日：2022-12-08

申请号：US17773001

申请日：2020-09-18

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Cheol Woong Ha ,  Eun Bin Yang ,  Hyo Jin Kim ,  Hyung Joon Kim ,  Yeong Eun Im

IPC: A61K36/064 ,  A23K20/147 ,  A23L33/18 ,  A23L33/145 ,  A23K10/16 ,  A61K38/06 ,  A61K8/9728 ,  A61K8/64 ,  C12N1/18

Abstract: Provided are a novel yeast strain producing glutathione and a method of producing glutathione using the same.

公开(公告)号：US20230056278A1

公开(公告)日：2023-02-23

申请号：US17790619

申请日：2021-04-02

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Cheol Woong Ha ,  Yeong Eun Im ,  Eun Bin Yang ,  Yeonsoo Kim ,  Hyung Joon Kim

IPC: C12P21/02 ,  C12N15/81 ,  C12N9/00

Abstract: Provided are a novel promoter, a vector including the same, a microorganism including the same, and a method of producing glutathione using the same.

公开(公告)号：US10227618B2

公开(公告)日：2019-03-12

申请号：US15735074

申请日：2016-06-10

Applicant: CJ Cheiljedang Corporation

Inventor： Seon Hye Kim ,  Tae Hee Lee ,  Young Lyeol Yang ,  Eun Bin Yang ,  Kyungsu Na ,  Cheol Woong Ha

IPC: C12N9/90 ,  C12P7/56 ,  C12N1/14 ,  C07K14/395 ,  C12N15/81

Abstract: The present application relates to a microorganism of the genus Saccharomyces producing lactic acid and a method for preparing lactic acid using the same. More specifically, the present application relates to a microorganism of the genus Saccharomyces producing lactic acid, wherein the microorganism is modified to weaken or inactivate the activity of pyruvate decarboxylase (PDC) compared to its endogenous activity, to introduce the activity of ATP-citrate lyase (ACL), and to enhance pyruvate biosynthetic pathway compared to its endogenous biosynthetic pathway, and a method for producing lactic acid using the microorganism.

公开(公告)号：US20180201960A1

公开(公告)日：2018-07-19

申请号：US15918995

申请日：2018-03-12

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Eun Bin Yang ,  Tae Hee Lee ,  Seon Hye Kim ,  Gyu Hyeon Song ,  Cheol Woong Ha ,  Kyung Su Na ,  Young Lyeol Yang ,  Min Sun Kang ,  Hyo Hyoung Lee

IPC: C12P7/56 ,  C12N9/04 ,  C12N9/88 ,  C12N9/02 ,  C12N9/00

CPC classification number: C12P7/56 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/88 ,  C12N9/93 ,  C12Y101/01027 ,  C12Y101/01028 ,  C12Y401/01001 ,  C12Y602/01001

Abstract: The present invention relates to Saccharomyces sp. capable of producing lactic acid with a decreased activity of pyruvate decarboxylase (PDC) and increased activities of aldehyde dehydrogenase (ALD) and acetyl-CoA synthetase (ACS), and a method of producing lactic acid from the culture medium obtained by culturing the microorganism.

公开(公告)号：US10155967B2

公开(公告)日：2018-12-18

申请号：US15735096

申请日：2015-06-12

Applicant: CJ Cheiljedang Corporation

Inventor： Eun Bin Yang ,  Tae Hee Lee ,  Seon Hye Kim ,  Gyuhyeon Song ,  Cheol Woong Ha ,  Kyungsu Na ,  Young Lyeol Yang ,  Min Sun Kang ,  Hyo Hyoung Lee

IPC: C12N1/14 ,  C12P7/56 ,  C12N1/18 ,  C12N9/02 ,  C12N9/88 ,  C12N9/00

Abstract: The present invention relates to Saccharomyces sp. capable of producing lactic acid with a decreased activity of pyruvate decarboxylase (PDC) and increased activities of aldehyde dehydrogenase (ALD) and acetyl-CoA synthetase (ACS), and a method of producing lactic acid from the culture medium obtained by culturing the microorganism.

公开(公告)号：US10138500B2

公开(公告)日：2018-11-27

申请号：US14397117

申请日：2013-04-24

Applicant: CJ Cheiljedang Corporation

Inventor： Eun Bin Yang ,  Tae Hee Lee ,  Seon Hye Kim ,  Young Lyeol Yang ,  Hong Xian Li

IPC: C12P7/56 ,  C12N9/04

Abstract: The present invention relates to a method for preparing a D-lactic acid-producing strain modified to inhibit L-lactate dehydrogenase (L-LDH) activity and to introduce D-lactate dehydrogenase (D-LDH) activity in an L-lactic acid-producing strain, a mutated D-lactic acid-producing strain prepared by the above method, and a method for producing D-lactic acid including the steps of culturing the strain and recovering D-lactic acid from the culture media.