公开(公告)号：US10968467B2

公开(公告)日：2021-04-06

申请号：US16447814

申请日：2019-06-20

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ji Sun Lee ,  Kwang Ho Lee ,  Hyo Jin Kim ,  Keun Chul Lee ,  Young Bin Hwang

IPC: C12P13/08 ,  C07K14/245 ,  C12N1/21 ,  C12N9/12

Abstract: The present invention relates to a novel variant RNA polymerase sigma factor 70 (σ70) polypeptide, a polynucleotide encoding the same, a microorganism containing the polypeptide, and a method for producing L-threonine by using the microorganism.

公开(公告)号：US10179903B2

公开(公告)日：2019-01-15

申请号：US15302738

申请日：2015-04-07

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyun Won Bae ,  Jun Ok Moon ,  Sung Ki Song ,  Hyung Joon Kim ,  Hyo Jin Kim ,  Sang Jo Lim

IPC: C12N1/20 ,  C12N9/12 ,  C12P13/08 ,  C12N9/10 ,  C12N15/77

Abstract: The present invention relates to a microorganism having improved L-lysine-producing ability and an L-lysine-producing method using the same. More specifically, the present invention relates to a microorganism of the genus of Corynebacterium, in which acetate kinase activity is further enhanced over inherent activity, and an L-lysine-producing method using the same.

公开(公告)号：US20180135031A1

公开(公告)日：2018-05-17

申请号：US15302738

申请日：2015-04-07

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyun Won Bae ,  Jun Ok Moon ,  Sung Ki Song ,  Hyung Joon Kim ,  Hyo Jin Kim ,  Sang Jo Lim

IPC: C12N9/12 ,  C12P13/08 ,  C12N15/77 ,  C12N9/10

CPC classification number: C12N9/1217 ,  C12N9/1029 ,  C12N15/77 ,  C12P13/08 ,  C12Y203/01008 ,  C12Y207/02001

Abstract: The present invention relates to a microorganism having improved L-lysine-producing ability and an L-lysine-producing method using the same. More specifically, the present invention relates to a microorganism of the genus of Corynebacterium, in which acetate kinase activity is further enhanced over inherent activity, and an L-lysine-producing method using the same.

公开(公告)号：US11312982B2

公开(公告)日：2022-04-26

申请号：US16930082

申请日：2020-07-15

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ji Sun Lee ,  Kwang Ho Lee ,  Hyo Jin Kim ,  Keun Chul Lee ,  Young Bin Hwang

IPC: C12P13/08 ,  C12N15/31 ,  C07K14/245 ,  C12N9/12

Abstract: The present invention relates to a novel variant RNA polymerase sigma factor 70 (δ70) polypeptide, a polynucleotide encoding the same, a microorganism containing the polypeptide, and a method for producing L-threonine by using the microorganism.

公开(公告)号：US11236374B2

公开(公告)日：2022-02-01

申请号：US16483309

申请日：2019-05-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyo Jin Kim ,  Lan Huh ,  Sang Jo Lim ,  Hyun Ah Kim ,  Hyoung Joon Kim ,  Chang il Seo ,  Seung Bin Lee ,  Ji Sun Lee

IPC: C12P13/06 ,  C12N1/20 ,  C12P13/08 ,  C12P13/12 ,  C12N9/04

Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.

公开(公告)号：US10760108B2

公开(公告)日：2020-09-01

申请号：US15117437

申请日：2015-09-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ji Sun Lee ,  Kwang Ho Lee ,  Hyo Jin Kim ,  Keun Chul Lee ,  Young Bin Hwang

IPC: C12P13/08 ,  C07K14/245 ,  C12N1/21 ,  C12N9/12

Abstract: The present invention relates to a novel variant RNA polymerase sigma factor 70 (π70) polypeptide, a polynucleotide encoding the same, a microorganism containing the polypeptide, and a method for producing L-threonine by using the microorganism.

公开(公告)号：US11555213B2

公开(公告)日：2023-01-17

申请号：US17472028

申请日：2021-09-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyo Jin Kim ,  Lan Huh ,  Sang Jo Lim ,  Hyun Ah Kim ,  Hyoung Joon Kim ,  Chang il Seo ,  Seung Bin Lee ,  Ji Sun Lee

IPC: C12N9/04 ,  C12P13/06 ,  C12N1/20 ,  C12P13/08 ,  C12P13/12

Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.

公开(公告)号：US20220387532A1

公开(公告)日：2022-12-08

申请号：US17773001

申请日：2020-09-18

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Cheol Woong Ha ,  Eun Bin Yang ,  Hyo Jin Kim ,  Hyung Joon Kim ,  Yeong Eun Im

IPC: A61K36/064 ,  A23K20/147 ,  A23L33/18 ,  A23L33/145 ,  A23K10/16 ,  A61K38/06 ,  A61K8/9728 ,  A61K8/64 ,  C12N1/18

Abstract: Provided are a novel yeast strain producing glutathione and a method of producing glutathione using the same.

公开(公告)号：US10995378B2

公开(公告)日：2021-05-04

申请号：US16479749

申请日：2019-02-22

Applicant: CJ Cheiljedang Corporation

Inventor： Moo Young Jung ,  Chang Il Seo ,  Hyo Jin Kim ,  Tae Yeon Kim ,  Hyun Ah Kim ,  Sung Kwang Son ,  Hye Ryun Yoo ,  Jae Min Lee ,  Ki Yong Cheong

IPC: C12P13/22 ,  C12N1/21 ,  C07K14/195 ,  C12R1/19 ,  C12N15/70 ,  C12N15/77 ,  C12R1/15

Abstract: The present disclosure relates to a microorganism producing L-tryptophan in which the microorganism is modified such that a protein having an L-tryptophan-exporting activity comprising the amino acid sequence of SEQ ID NO: 1 is expressed, and a method for producing L-tryptophan using the microorganism.

公开(公告)号：US10662450B2

公开(公告)日：2020-05-26

申请号：US16344189

申请日：2018-06-29

Applicant: CJ Cheiljedang Corporation

Inventor： Hyung Joon Kim ,  Hyo Jin Kim ,  Hyun Won Bae ,  Hyun Ah Kim ,  Chang Il Seo ,  Ji Sun Lee ,  Jin Sook Chang

IPC: C12P13/02 ,  C12N15/77 ,  C12N9/12

Abstract: An aspartokinase variant, a microorganism comprising the variant, and a method for producing an aspartate-derived L-amino acid or a homoserine derivative thereof using the microorganism.