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1.
公开(公告)号:US20240266064A1
公开(公告)日:2024-08-08
申请号:US18614586
申请日:2024-03-22
Applicant: Cleerly, Inc.
Inventor: James K. Min , James P. Earls , Shant Malkasian , Hugo Miguel Rodrigues Marques , Chung Chan , Shai Ronen
CPC classification number: G16H50/30 , A61B5/02028 , A61B5/4848 , G06T7/0016 , G06T7/10 , G06T7/60 , G06V20/50 , G16H30/40 , G06T2207/10048 , G06T2207/10081 , G06T2207/10088 , G06T2207/10101 , G06T2207/10104 , G06T2207/10108 , G06T2207/10116 , G06T2207/10132 , G06T2207/20081 , G06T2207/30048 , G06T2207/30101 , G06V2201/031
Abstract: Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and/or track coronary artery disease.
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2.
公开(公告)号:US11922627B2
公开(公告)日:2024-03-05
申请号:US18454462
申请日:2023-08-23
Applicant: Cleerly, Inc.
Inventor: James K. Min , James P. Earls , Shant Malkasian , Hugo Miguel Rodrigues Marques , Chung Chan , Shai Ronen
CPC classification number: G06T7/0012 , A61B5/7275 , G06T7/62 , G06T2207/10048 , G06T2207/10081 , G06T2207/10101 , G06T2207/10104 , G06T2207/10108 , G06T2207/10116 , G06T2207/10132 , G06T2207/20081 , G06T2207/30101
Abstract: Systems and methods of facilitating determination of risk of coronary artery disease (CAD) based at least in part on one or more measurements derived from non-invasive medical image analysis. The methods can include accessing a non-invasive generated medical image, identifying one or more arteries, identifying, regions of plaque within an artery, analyzing the regions of plaque to identify low density non-calcified plaque, non-calcified plaque, or calcified plaque based at least in part on density, determining a distance from identified regions of low density non-calcified plaque to one or more of a lumen wall or vessel wall, determining embeddedness of the regions of low density non-calcified plaque by one or more of non-calcified plaque or calcified plaque, determining a shape of the more regions of low density non-calcified plaque, and generating a display of the analysis to facilitate determination of one or more of a risk of CAD of the subject.
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3.
公开(公告)号:US20230401711A1
公开(公告)日:2023-12-14
申请号:US18456341
申请日:2023-08-25
Applicant: Cleerly, Inc.
Inventor: James K. Min , James P. Earls , Shant Malkasian , Hugo Miguel Rodrigues Marques , Chung Chan , Shai Ronen
CPC classification number: G06T7/0012 , A61B5/7275 , G06T7/62 , G06T2207/10108 , G06T2207/10101 , G06T2207/10081 , G06T2207/30101 , G06T2207/20081 , G06T2207/10104 , G06T2207/10116 , G06T2207/10048 , G06T2207/10132
Abstract: Systems and methods of facilitating determination of risk of coronary artery disease (CAD) based at least in part on one or more measurements derived from non-invasive medical image analysis. The methods can include accessing a non-invasive generated medical image, identifying one or more arteries, identifying, regions of plaque within an artery, analyzing the regions of plaque to identify low density non-calcified plaque, non-calcified plaque, or calcified plaque based at least in part on density, determining a distance from identified regions of low density non-calcified plaque to one or more of a lumen wall or vessel wall, determining embeddedness of the regions of low density non-calcified plaque by one or more of non-calcified plaque or calcified plaque, determining a shape of the more regions of low density non-calcified plaque, and generating a display of the analysis to facilitate determination of one or more of a risk of CAD of the subject.
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公开(公告)号:US20220392065A1
公开(公告)日:2022-12-08
申请号:US17820439
申请日:2022-08-17
Applicant: CLEERLY, INC.
Inventor: James K. Min , James P. Earls , Hugo Miguel Rodrigues Marques , Shant Malkasian , Ben Hootnick
IPC: G06T7/00 , A61B8/14 , A61B6/00 , A61B6/03 , A61B5/00 , A61B8/12 , G06K9/62 , A61B5/055 , A61K49/04
Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, perform computational fluid dynamics analysis, facilitate assessment of risk of heart disease and coronary artery disease, enhance drug development, determine a CAD risk factor goal, provide atherosclerosis and vascular morphology characterization, and determine indication of myocardial risk, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.
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公开(公告)号:US12141976B2
公开(公告)日:2024-11-12
申请号:US18586145
申请日:2024-02-23
Applicant: CLEERLY, INC.
Inventor: James K. Min , James P. Earls , Hugo Miguel Rodrigues Marques , Shant Malkasian , Ben Hootnick
IPC: G06T7/00 , A61B5/00 , A61B5/055 , A61B6/00 , A61B6/03 , A61B6/50 , A61B8/12 , A61B8/14 , A61K49/04
Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, perform computational fluid dynamics analysis, facilitate assessment of risk of heart disease and coronary artery disease, enhance drug development, determine a CAD risk factor goal, provide atherosclerosis and vascular morphology characterization, and determine indication of myocardial risk, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.
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公开(公告)号:US11967078B2
公开(公告)日:2024-04-23
申请号:US18148995
申请日:2022-12-30
Applicant: CLEERLY, INC.
Inventor: James K. Min , James P. Earls , Hugo Miguel Rodrigues Marques , Shant Malkasian , Ben Hootnick
IPC: G06T7/00 , A61B5/00 , A61B5/055 , A61B6/00 , A61B6/03 , A61B6/50 , A61B8/12 , A61B8/14 , A61K49/04 , G06F18/10
CPC classification number: G06T7/0012 , A61B5/0066 , A61B5/0075 , A61B5/055 , A61B5/7267 , A61B5/742 , A61B5/7475 , A61B6/032 , A61B6/037 , A61B6/481 , A61B6/504 , A61B6/5205 , A61B8/12 , A61B8/14 , A61K49/04 , G06F18/10 , G06T2207/10081 , G06T2207/10088 , G06T2207/10101 , G06T2207/10132 , G06T2207/20081 , G06T2207/30048 , G06T2207/30101
Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, perform computational fluid dynamics analysis, facilitate assessment of risk of heart disease and coronary artery disease, enhance drug development, determine a CAD risk factor goal, provide atherosclerosis and vascular morphology characterization, and determine indication of myocardial risk, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.
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7.
公开(公告)号:US20230289963A1
公开(公告)日:2023-09-14
申请号:US18179921
申请日:2023-03-07
Applicant: Cleerly, Inc.
Inventor: James K. Min , James P. Earls , Shant Malkasian , Hugo Miguel Rodrigues Marques , Chung Chan , Shai Ronen
CPC classification number: G06T7/0012 , G06T7/62 , A61B5/7275 , G06T2207/30101 , G06T2207/20081 , G06T2207/10081 , G06T2207/10108 , G06T2207/10104 , G06T2207/10101 , G06T2207/10116 , G06T2207/10132 , G06T2207/10048
Abstract: Systems and methods of facilitating determination of risk of coronary artery disease (CAD) based at least in part on one or more measurements derived from non-invasive medical image analysis. The methods can include accessing a non-invasive generated medical image, identifying one or more arteries, identifying, regions of plaque within an artery, analyzing the regions of plaque to identify low density non-calcified plaque, non-calcified plaque, or calcified plaque based at least in part on density, determining a distance from identified regions of low density non-calcified plaque to one or more of a lumen wall or vessel wall, determining embeddedness of the regions of low density non-calcified plaque by one or more of non-calcified plaque or calcified plaque, determining a shape of the more regions of low density non-calcified plaque, and generating a display of the analysis to facilitate determination of one or more of a risk of CAD of the subject.
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公开(公告)号:US20230237654A1
公开(公告)日:2023-07-27
申请号:US18149014
申请日:2022-12-30
Applicant: CLEERLY, INC.
Inventor: James K. Min , James P. Earls , Hugo Miguel Rodrigues Marques , Shant Malkasian , Ben Hootnick
IPC: G06T7/00 , A61B8/14 , A61B6/00 , A61B6/03 , A61B5/00 , A61B8/12 , A61B5/055 , A61K49/04 , G06F18/10
CPC classification number: G06T7/0012 , A61B5/055 , A61B5/0066 , A61B5/0075 , A61B5/742 , A61B5/7267 , A61B5/7475 , A61B6/032 , A61B6/037 , A61B6/481 , A61B6/504 , A61B6/5205 , A61B8/12 , A61B8/14 , A61K49/04 , G06F18/10 , G06T2207/10081 , G06T2207/10088 , G06T2207/10101 , G06T2207/10132 , G06T2207/20081 , G06T2207/30048 , G06T2207/30101
Abstract: The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, perform computational fluid dynamics analysis, facilitate assessment of risk of heart disease and coronary artery disease, enhance drug development, determine a CAD risk factor goal, provide atherosclerosis and vascular morphology characterization, and determine indication of myocardial risk, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.
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9.
公开(公告)号:US20240266066A1
公开(公告)日:2024-08-08
申请号:US18614595
申请日:2024-03-22
Applicant: Cleerly, Inc.
Inventor: James K. Min , James P. Earls , Shant Malkasian , Hugo Miguel Rodrigues Marques , Chung Chan , Shai Ronen
CPC classification number: G16H50/30 , A61B5/02028 , A61B5/4848 , G06T7/0016 , G06T7/10 , G06T7/60 , G06V20/50 , G16H30/40 , G06T2207/10048 , G06T2207/10081 , G06T2207/10088 , G06T2207/10101 , G06T2207/10104 , G06T2207/10108 , G06T2207/10116 , G06T2207/10132 , G06T2207/20081 , G06T2207/30048 , G06T2207/30101 , G06V2201/031
Abstract: Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and/or track coronary artery disease.
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10.
公开(公告)号:US20240266063A1
公开(公告)日:2024-08-08
申请号:US18614580
申请日:2024-03-22
Applicant: Cleerly, Inc.
Inventor: James K. Min , James P. Earls , Shant Malkasian , Hugo Miguel Rodrigues Marques , Chung Chan , Shai Ronen
CPC classification number: G16H50/30 , A61B5/02028 , A61B5/4848 , G06T7/0016 , G06T7/10 , G06T7/60 , G06V20/50 , G16H30/40 , G06T2207/10048 , G06T2207/10081 , G06T2207/10088 , G06T2207/10101 , G06T2207/10104 , G06T2207/10108 , G06T2207/10116 , G06T2207/10132 , G06T2207/20081 , G06T2207/30048 , G06T2207/30101 , G06V2201/031
Abstract: Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and/or track coronary artery disease.
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