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公开(公告)号：US11098292B2
公开(公告)日：2021-08-24
申请号：US16790534
申请日：2020-02-13
申请人： Codexis, Inc.
IPC分类号： C12N15/70 , C12N15/00 , C12N15/54 , C07H21/04 , C12N9/10 , C12P13/00 , C12P17/18 , C07D487/04
摘要： The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
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公开(公告)号：US09963685B2
公开(公告)日：2018-05-08
申请号：US15443792
申请日：2017-02-27
申请人： Codexis, Inc.
IPC分类号： C12P13/00 , C12P17/18 , C12N9/10 , C07D487/04 , C12P17/08
CPC分类号： C12N9/1096 , C07D487/04 , C12P13/001 , C12P17/182 , C12Y206/01
摘要： The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
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公开(公告)号：US20160002688A1
公开(公告)日：2016-01-07
申请号：US14768408
申请日：2014-02-24
申请人： CODEXIS, INC.
CPC分类号： C12N9/1096 , C07D487/04 , C12P13/001 , C12P17/182 , C12Y206/01
摘要： The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
摘要翻译： 本公开提供了可用于在工业上相关条件下合成手性胺化合物的工程化转氨酶多肽。 本公开还提供编码工程改造的转氨酶多肽的多核苷酸，能够表达工程化转氨酶的宿主细胞，以及使用工程转氨酶来生产手性胺化合物的方法。
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公开(公告)号：US20200172882A1
公开(公告)日：2020-06-04
申请号：US16790534
申请日：2020-02-13
申请人： Codexis, Inc.
IPC分类号： C12N9/10 , C07D487/04 , C12P17/18 , C12P13/00
摘要： The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
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公开(公告)号：US09617573B2
公开(公告)日：2017-04-11
申请号：US14768408
申请日：2014-02-24
申请人： Codexis, Inc.
CPC分类号： C12N9/1096 , C07D487/04 , C12P13/001 , C12P17/182 , C12Y206/01
摘要： The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
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公开(公告)号：US20170175090A1
公开(公告)日：2017-06-22
申请号：US15443792
申请日：2017-02-27
申请人： Codexis, Inc.
IPC分类号： C12N9/10 , C12P17/18 , C12P13/00 , C07D487/04
CPC分类号： C12N9/1096 , C07D487/04 , C12P13/001 , C12P17/182 , C12Y206/01
摘要： The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
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公开(公告)号：US20210348138A1
公开(公告)日：2021-11-11
申请号：US17379563
申请日：2021-07-19
申请人： Codexis, Inc.
IPC分类号： C12N9/10 , C12P13/00 , C12P17/18 , C07D487/04
摘要： The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
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公开(公告)号：US10604744B2
公开(公告)日：2020-03-31
申请号：US15945549
申请日：2018-04-04
申请人： Codexis, Inc.
IPC分类号： C12P13/00 , C12P17/18 , C12P17/08 , C12N9/10 , C07D487/04
摘要： The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
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公开(公告)号：US20180223265A1
公开(公告)日：2018-08-09
申请号：US15945549
申请日：2018-04-04
申请人： Codexis, Inc.
IPC分类号： C12N9/10 , C12P13/00 , C12P17/18 , C07D487/04
CPC分类号： C12N9/1096 , C07D487/04 , C12P13/001 , C12P17/182 , C12Y206/01
摘要： The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The disclosure also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.
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